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Journal of Genetic Engineering and Biotechnology
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  1. The production of industrial enzymes such as xylanase using sufficient cost-effective substrates from potent microorganisms is considered economically feasible. Studies have reported castor cake (Ricinus communis

    Authors: Shaimaa A. Nour, Ghada M. El-Sayed, Hanan A. A. Taie, Maha T. H. Emam, Ahmed F. El-Sayed and Rasha G. Salim
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:121
    Content type: Research Published on:

  2. Intrinsic pathway of apoptosis is generally mediated by BCL-2 (B cell lymphoma 2) family of proteins; they either induce or inhibit the apoptosis. Overexpression of BCL-2 in cancer cell may lead to delay in ap...

    Authors: Poonam Kumari and Rashmi Rameshwari
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:120
    Content type: Research Published on:

  3. Arthrogryposis is a medical term used to describe congenital contractures which often affect multiple limbs. Distal arthrogryposis (DA) is one of the major categories of arthrogryposis that primarily affects t...

    Authors: Anik Biswas, Sudipta Deb Nath, Tamim Ahsan, M. Monir Hossain, Sharif Akhteruzzaman and Abu Ashfaqur Sajib
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:119
    Content type: Research Published on:

  4. Aeromonas veronii is one of the most common pathogens of freshwater fishes that cause sepsis and ulcers. There are increasing numbers of cases showing that it is a significant zoonotic and aquatic agent. Epidemi...

    Authors: Sk Injamamul Islam, Moslema Jahan Mou and Saloa Sanjida
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:118
    Content type: Research Published on:

  5. Interstitial lung disease (ILD) is a broad heterogeneous group of lung disorders that is characterized by inflammation of the lungs. Surfactant dysfunction disorders are a rare form of ILD diseases that result...

    Authors: Azza K. Abdel Megeid, Miral M. Refeat, Engy A. Ashaat, Ghada El-Kamah, Sonia A. El-Saiedi, Mona M. Elfalaki, Mona O. El Ruby and Khalda S. Amr
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:117
    Content type: Research Published on:

  6. Capsicum or chilli is an important crop in India which exhibits immense structural and genetic variations reflecting their intra- and inter-specific relationships. The aim of this study was to establish relations...

    Authors: Shamshadul Haq, Shikha Dubey, Prerna Dhingra, Kumar Sambhav Verma, Deepa Kumari, S. L. Kothari and Sumita Kachhwaha
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:116
    Content type: Research Published on:

  7. Nowadays, the conventional plastic wastes are very challenging to environments and its production cost also creates an economic crisis due to petrochemical-based plastic. In order to solve this problem, the cu...

    Authors: Seid Mohammed and Lopamudra Ray
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:115
    Content type: Research Published on:

  8. The X-chromosome short tandem repeat (STR) polymorphisms are a particular tool in the fields of human population genetics and personal identification. It was necessary in investigating complex kinship or defic...

    Authors: Salwa J. Al-Awadi, Hayder A. Khaleefah and Shaimaa Y. Abdulfattah
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:114
    Content type: Research Published on:

  9. Endophytic bacteria overlay significant role in plant growth promotion, eliminating phyto-pathogens and combating stress-conditions. In the present study, we aimed to screen high salt tolerant bacteria and stu...

    Authors: Namita Bhutani, Rajat Maheshwari, Nidhi Sharma, Pradeep Kumar, Amita Suneja Dang and Pooja Suneja
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:113
    Content type: Research Published on:

  10. The prenatal diagnosis of syndromes caused by chromosomal abnormality is a long-established part of obstetric care. Several DNA-based molecular approaches have provided rapid prenatal diagnosis of of cytogenom...

    Authors: Ola M. Eid, Maha M. Eid, Marwa Farid, Rania M. A. Abdel Kader, Rana Mahrous and Sara H. El-Dessouky
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:112
    Content type: Research Published on:

  11. The production of monoclonal antibodies for immunoglobulin detection is not cost-effective, while polyclonal antibody production depends on laboratory animals, raising concerns on animal welfare. The widesprea...

    Authors: Anelize Felicio Ramos, Leonardo Antônio Fernandes, Franciane Batista, Bianca de Souza Vieira, Mayerson Thompson, Jacó Joaquim Mattos, Maria Risoleta Freire Marques, Maria de Lourdes Borba Magalhães and Gustavo Felippe da Silva
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:111
    Content type: Research Published on:

  12. This study aimed to explore the association between polymorphisms in three genes: leptin (LEP), leptin receptor (LEPR), and BMP4, and incidence of repeat breeding in Egyptian buffaloes.

    Authors: Karima F. Mahrous, Heba A. M. Abd El -Kader, Mohamad A. Abdelhafez, Mohamad M. Aboelenin, Esraa A. Balabel, Dalia M. Mabrouk, Osama M. EL Malky and Mohamed S. Hassanane
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:110
    Content type: Research Published on:

  13. Global food supply is highly dependent on field crop production that is currently severely threatened by changing climate, poor soil quality, abiotic, and biotic stresses. For instance, one of the major challe...

    Authors: Simon W. Mburu, Gilbert Koskey, Ezekiel M. Njeru, Omwoyo Ombori, John Maingi and Jacinta M. Kimiti
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:109
    Content type: Research Published on:

  14. COVID-19 has become a pandemic, and any new drug for treating the disease could save millions of lives. Several drugs already in use for other diseases and medical conditions are repurposed for treating COVID-...

    Authors: Sellappan Mohan, Jayagopal Dharani, Ramanathan Natarajan and Arumugam Nagarajan
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:108
    Content type: Research Published on:

  15. The present study was designed to develop an improved in vitro regeneration system for Dioscorea bulbifera using mature nodal explants. Direct organogenesis from nodal segments was achieved by culturing the nodal...

    Authors: Musadiq Hussain Bhat, Mufida Fayaz, Amit Kumar, Alamgir A. Dar and Ashok Kumar Jain
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:107
    Content type: Research Published on:

  16. In recent years, major advance in molecular biology and genomic technologies have led to an exponential growth in biological information. As the deluge of genomic information, there is a parallel growth in the...

    Authors: Yung Cheng Tan, Asqwin Uthaya Kumar, Ying Pei Wong and Anna Pick Kiong Ling
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:106
    Content type: Review Published on:

  17. Citrus species are among the most important and widely consumed fruit trees in the world and are subjected to increasing global cultivation. Sweet orange (Citrus sinensis L. Osbeck) is one of 30 species of citrus...

    Authors: Narineh Shahnazari, Zahra Noormohammadi, Masoud Sheidai and Fahimeh Koohdar
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:105
    Content type: Research Published on:

  18. DNA damage and genome instability in host cells are introduced by many viruses during their life cycles. Severe acute respiratory syndrome coronaviruses (SARS-CoVs) manipulation of DNA damage response (DDR) is...

    Authors: Asmaa S. Mekawy, Zina Alaswad, Aya A. Ibrahim, Ahmed A. Mohamed, Abdelrahman AlOkda and Menattallah Elserafy
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:104
    Content type: Review Published on:

  19. Small RNAs (sRNAs) that do not get untranslated into proteins exhibit a pivotal role in the expression regulation of their cognate gene(s) in almost all eukaryotic lineages, including plants. Hitherto, numerou...

    Authors: Behzad Hajieghrari, Naser Farrokhi and Mojahed Kamalizadeh
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:103
    Content type: Research Published on:

  21. Plants use escape strategies including premature senescence and leaf reduction to cope in response to drought stress, which in turn reduces plant leaves and photosynthesis. This strategy allows the new generat...

    Authors: Zohreh Hajibarat and Abbas Saidi
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:101
    Content type: Review Published on:

  22. Burkholderia pseudomallei is an infectious agent causing severe disease melioidosis resulting in pneumonia, fever, and acute septicemia in humans. B. pseudomallei show resistance to drugs. No such FDA-approved va...

    Authors: Muhammad Shahab, Chandni Hayat, Ramin Sikandar, Guojun Zheng and Shahina Akter
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:100
    Content type: Research Published on:

  23. The freshwater snails Biomphalaria alexandrina (Gastropoda: Planorbidae) has public health importance of being an intermediate host of Schistosoma mansoni, the parasite species that causes intestinal schistosomia...

    Authors: Abdel-Monem Abdalla and Ghada S. A. Abdel Karim
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:99
    Content type: Research Published on:

  24. The baculovirus expression vector system has been developed for expressing a wide range of proteins, including enzymes, glycoproteins, recombinant viruses, and vaccines. The availability of the SARS-CoV-2 geno...

    Authors: Muhammad Azharuddin Azali, Salmah Mohamed, Azian Harun, Faezahtul Arbaeyah Hussain, Shaharum Shamsuddin and Muhammad Farid Johan
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:98
    Content type: Review Published on:

  25. Preferentially expressed antigen of melanoma (PRAME) gene is regularly overexpressed in acute leukemia (AL) and other malignant diseases which are recognized by human leucocyte antigen (HLA-24) located in the ...

    Authors: Nagaraj V. Kulkarni, Reshma A. Shetty, Suchetha Kumari N, Vijith V. Shetty, Rajesh Krishna, Meenakshi Arumugam, Akanksha A. Kalal and Prashanth Shetty
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:97
    Content type: Research Published on:

  26. Gaining insight into crop diversity, both at the genetic and phenotypic levels, is of prime importance for onion breeding with an enhanced yield and quality in combination with improved resistance to biotic an...

    Authors: Amal Brahimi, Sofie Landschoot, Boris Bekaert, Lhoussain Hajji, Hassan Hajjaj, Kris Audenaert, Geert Haesaert and Hamid Mazouz
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:96
    Content type: Research Published on:

  27. Mastitis is an inflammation of the mammary glands caused by a microbial infection. The common bacteria causing this infection in dairy farms are Staphylococcus aureus, Streptococcus agalactiae, and Escherichia co...

    Authors: Arizah Kusumawati, Apon Zaenal Mustopa, I. Wayan Teguh Wibawan, Agus Setiyono and Mirnawati Bachrum Sudarwanto
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:95
    Content type: Research Published on:

  29. Synthesized gallium nanoparticles synthesized by grape seed extract were characterized with spherical shape and size range less than100 nm, possessing the functional groups of the biological material. The purp...

    Authors: Mohga S. Abdalla, El-Sayed M. El-Mahdy, Somaya Z. Mansour, Sawsan M. Elsonbaty and Menna H. Amin
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:93
    Content type: Research Published on:

  30. Single-nucleotide polymorphisms (SNPs) have a crucial function in affecting the susceptibility of individuals to diseases and also determine how an individual responds to different treatment options. The prese...

    Authors: Harini Venkata Subbiah, Polani Ramesh Babu and Usha Subbiah
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:92
    Content type: Research Published on:

  31. The utilization of bioluminescent bacteria in environmental monitoring of water contaminates considers being a vital and powerful approach. This study aimed to isolate, optimize, and apply luminescent bacteria...

    Authors: Howaida Hassan, Marwa Eltarahony, Gadallah Abu-Elreesh, Hanan M. Abd-Elnaby, Soraya Sabry and Hanan Ghozlan
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:91
    Content type: Research Published on:

  32. Owing to its remarkable mechanical properties that surpass the plant-based cellulose, bacterial cellulose production has been targeted for commercialization during the last few years. However, the large-scale ...

    Authors: Saif S. Al-Janabi, Heba Shawky, Amr A. El-Waseif, Ayman A. Farrag, Tarek M. Abdelghany and Dina E. El-Ghwas
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:90
    Content type: Research Published on:

  33. Bunyumwera virus can cause 82% mortality in humans currently with no vaccine or drugs for treatment. We described an in silico multi-epitope vaccine targeting Bunyumwera virus nucleocapsid N-protein and predic...

    Authors: Kanaka Durga Devi Nelluri, Manne Anupama Ammulu, M. Lakshmi Durga, Melika Sravani, Vemuri Praveen Kumar and Sudhakar Poda
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:89
    Content type: Research Published on:

  34. In seek of potent and non-toxic iminoguanidine derivatives formerly assessed as active Pseudomonas aeruginosa inhibitors, a combined mathematical approach of quantitative structure-activity relationship (QSAR)...

    Authors: Emmanuel Israel Edache, Adamu Uzairu, Paul Andrew Mamza and Gideon Adamu Shallangwa
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:88
    Content type: Research Published on:

  35. Lignocellulosic biomasses produced from agriculture and forest-based industries are the cheapest or negative-cost biomass with a great potential for biotransformation to value-added bioproducts. Paper mill slu...

    Authors: Tuhin Das, Ferdausi Ali and Md. Shafiqur Rahman
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:87
    Content type: Research Published on:

  36. Aegilops tauschii Coss. as a donor of wheat D genome has an important role in wheat breeding programs. Genetic and phylogeographic diversity of 79 Ae. tauschii accessions collected from north and northwest of Ira...

    Authors: Sona Minaei, Seyyed Abolghasem Mohammadi, Atefeh Sabouri and Ahmad Reza Dadras
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:86
    Content type: Research Published on:

  37. This study was designed to generate functional insulin-producing cells (IPCs) from dental-derived mesenchymal stem cells (MSCs) and further explore their therapeutic potential against diabetes mellitus in vivo...

    Authors: Riham M. Aly, Hadeer A. Aglan, Ghada Nour Eldeen, Nadia S. Mahmoud, Eman H. Aboul-Ezz and Hanaa H. Ahmed
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:85
    Content type: Research Published on:

  38. Fibroblast growth factor 21 (FGF-21), alpha-amylase, and alpha-glucosidase are key proteins implicated in metabolic dysregulations. Bisphenol A (BPA) is an environmental toxicant known to cause endocrine dysre...

    Authors: P. M. Aja, J. N. Awoke, P. C. Agu, A. E. Adegboyega, E. M. Ezeh, I. O. Igwenyi, O. U. Orji, O. G. Ani, B. A. Ale and U. A. Ibiam
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:84
    Content type: Research Published on:

  39. Schizophrenia is a chronic mental disorder with different symptoms. The environmental and genetic factors are suggested to be the etiology of schizophrenia. However, the exact cause and pathogenesis of schizop...

    Authors: Maged Mostafa, Aya Ahmed Fathy, Mohamed Elwasify and Maha Abdelsalam
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:83
    Content type: Research Published on:

  40. Protease is one of the most important industrial enzymes. The importance of protease bioproduction comes from meeting the increasing demand for this enzyme especially in the cheese industry. Rhizomucor miehei pro...

    Authors: Houthail Alahmad Aljammas, Sabah Yazji and Abdulhakim Azizieh
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:82
    Content type: Research Published on:

  41. Antarctica is one of the harshest environments in the world. Despite this fact, it has been colonized by microorganisms, which had to develop different adaptations in order to survive. By studying their enzyme...

    Authors: P. Rios, B. Bezus, S. Cavalitto and I. Cavello
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:81
    Content type: Research Published on:

  42. Sugarcane hemicellulosic material is a compelling source of usually neglected xylose that could figure as feedstock to produce chemical building blocks of high economic value, such as xylitol. In this context, Sa...

    Authors: Fellipe da Silveira Bezerra de Mello, Carla Maneira, Frank Uriel Lizarazo Suarez, Sheila Nagamatsu, Beatriz Vargas, Carla Vieira, Thais Secches, Alessando L. V. Coradini, Maria Augusta de Carvalho Silvello, Rosana Goldbeck, Gonçalo Amarante Guimarães Pereira and Gleidson Silva Teixeira
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:80
    Content type: Research Published on:

  43. Successful rhizosphere colonization by plant growth promoting rhizobacteria (PGPR) is of crucial importance to perform the desired plant growth promoting activities. Since rhizocompetence is a dynamic process ...

    Authors: Donia S. Helal, Hussein El-khawas and Tarek R. Elsayed
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:79
    Content type: Research Published on:

  44. COVID-19 is an illness caused by severe acute respiratory syndrome coronavirus 2. Due to its rapid spread, in March 2020 the World Health Organization (WHO) declared pandemic. Since the outbreak of pandemic ma...

    Authors: Abas Sezer, Mervisa Halilović-Alihodžić, Annissa Rachel Vanwieren, Adna Smajkan, Amina Karić, Husein Djedović and Jasmin Šutković
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:78
    Content type: Review Published on:

  45. Newcastle disease virus (NDV) belongs to the genus Avaluvirus and Paramyxoviridae family, and it can cause acute, highly contagious Newcastle disease in poultry. The two proteins, haemagglutinin neuraminidase (HN...

    Authors: Mohammadreza Shafaati, Masoud Ghorbani, Minoo Mahmoodi, Mostafa Ebadi and Reza Jalalirad
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:77
    Content type: Research Published on:

  46. Many active peptides have been found in frog skin secretions. In this paper, our research focused on Pelophylax nigromaculatus and found a broad-spectrum antimicrobial peptide Nigrocin-PN based on the molecular c...

    Authors: Chengyu Lu, Lingling Liu, Chengbang Ma, Liuqing Di and Tianbao Chen
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:76
    Content type: Research Published on:

  47. Metabolic syndrome (MetS) is a combination of many health complications, such as obesity, high blood pressure, hyperlipidemia, hyperglycemia, and insulin resistance, with an increasing threat of type 2 diabete...

    Authors: Amira Mohamed Abd El-Jawad, Iman Hassan Ibrahim, Moushira Erfan Zaki, Tahany Ramzy Elias, Wafaa Ibrahim Rasheed and Khalda Said Amr
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:75
    Content type: Research Published on:

  48. Gongronella butleri is a fungus with many industrial applications including the composting of solid biowaste. Kerala Agricultural University, India, has developed a microbial consortium of which GbKAU strain of G...

    Authors: Ravisankar Valsalan, Deepu Mathew and Girija Devaki
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:74
    Content type: Research Published on:

  50. Among the most common causes of invasive aspergillosis and acute bronchopulmonary aspergillosis is Aspergillus fumigatus. Transmission with A. fumigatus produces aggressive aspergillosis in allogeneic haematopoie...

    Authors: Darakshan Jabin and Ajay Kumar
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:72
    Content type: Research Published on:
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  • ISSN: 2090-5920 (electronic)