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Journal of Genetic Engineering and Biotechnology
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  1. Hepatocellular carcinoma (HCC) is among the common cancers, but difficult to diagnose and treat. l-asparaginase has been introduced in the treatment protocol of pediatric acute lymphoblastic leukemia (ALL) since ...

    Authors: Dina H. El-Ghonemy, Sanaa A. Ali, Rehab M. Abdel-Megeed and Ali M. Elshafei
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:38
    Content type: Research Published on:

  2. Thermostable enzymes are enzymes that can withstand elevated temperatures as high as 50 °C without altering their structure or distinctive features. The potential of thermostable enzymes to increase the conver...

    Authors: Che Haznie Ayu Che Hussian and Wai Yie Leong
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:37
    Content type: Review Published on:

  3. The prevalence of diarrhoea remains high despite efforts by governments and NGOs to reverse trend. This study investigated the antidiarrhoeal activity and mechanism of Spondias mombin leaf fraction rich in querce...

    Authors: Olalekan Bukunmi Ogunro, Emmanuel Bankole Ofeniforo and Aderonke Elizabeth Fakayode
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:36
    Content type: Research Published on:

  4. The existence of mutated Delta (B.1.617.2) variants of SARS-CoV-2 causes rapid transmissibility, increase in virulence, and decrease in the effectiveness of public health. Majority of mutations are seen in the su...

    Authors: Sandhya KS and Achuthsankar S. Nair
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:35
    Content type: Research Published on:

  5. The cytochrome b (Cyt b) gene is one of the most studied mitochondrial DNA (mtDNA) genes to determine sheep’s genetic profile. This study aimed to determine the genetic diversity and relationships of several I...

    Authors: Alek Ibrahim, Endang Baliarti, I Gede Suparta Budisatria, Wayan Tunas Artama, Rini Widayanti, Dyah Maharani, Luis Tavares and Endang Tri Margawati
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:34
    Content type: Research Published on:

  6. Hepatitis E virus (HEV) is the cause of a liver disease hepatitis E. The translation product of HEV ORF2 has recently been demonstrated as a protein involved in multiple functions besides performing its major ...

    Authors: Zoya Shafat, Anwar Ahmed, Mohammad K. Parvez and Shama Parveen
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:33
    Content type: Research Published on:

  7. Seaweeds are a viable bioresource for suffering plants against salt stress, as they abundant in nutrients, hormones, vitamins, secondary metabolites, and many other phytochemicals that sustain plants' growth u...

    Authors: Marwa M. Hamouda, Abdelfattah Badr, Sameh S. Ali, Alia M. Adham, Hanan I. Sayed Ahmed and Khalil M. Saad-Allah
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:32
    Content type: Research Published on:

  8. Actinomycetes isolated from marine habitats are known to have the potential for novel enzymes that are beneficial in the industry. In-depth knowledge is necessary given the variety of this bacterial group in I...

    Authors: Hana Nadhifah, Nanik Rahmani, Wibowo Mangunwardoyo, Yopi, Akhirta Atikana, Shanti Ratnakomala and Puspita Lisdiyanti
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:31
    Content type: Research Published on:

  9. The Ag-NPs by green synthesis has a notable interest because of their eco-friendliness, economic views, feasibility, and applications in a wide range. Herein, native plants of Jharkhand (Polygonum plebeium, Litse...

    Authors: Koel Mukherjee, Namrata Bhagat, Madhubala Kumari, Arnab Roy Choudhury, Biplab Sarkar and Barnali Dasgupta Ghosh
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:30
    Content type: Research Published on:

  10. Phoebe goalparensis is an endemic forest species of North East India that belongs to Lauraceae family. P. goalparensis is used as timbers yielding plants for commercial importance in the local furniture markets o...

    Authors: Kalpataru Dutta Mudoi, Barbi Gogoi, Gitasree Borah, Marine Hussain, Tabassum Tasfia, Krishnakhi Borah, Himangshu Lekhak and Siddhartha Proteem Saikia
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:29
    Content type: Research Published on:

  11. Glutathione s-transferases (GSTs) perform an essential role in detoxification of xenobiotics and endogenous compounds via their conjugation to reduce glutathione.

    Authors: Hassan M. M. Masoud, Mohamed S. Helmy, Doaa A. Darwish and Mahmoud A. Ibrahim
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:28
    Content type: Research Published on:

  12. Saccharomyces cerevisiae (S. cerevisiae) has been demonstrated in vitro to sensitize several breast cancer cell lines and to be a safe, non-toxic drug with anti-skin cancer action in mice. Furthermore, plasmonic ...

    Authors: Amany Elwakkad, Amina A. Gamal el Din, Hisham A. Saleh, Noha E. Ibrahim, Mohamed A. Hebishy, Hagar H. Mourad, Mahitab I. El-Kassaby, Howida Sayed Abou-Seif and Ghada M. Elqattan
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:27
    Content type: Research Published on:

  13. Bletilla species are endangered terrestrial orchids used in natural skin care formulas in Asia for a long history. In order to explore the bioactivity potential of Bletilla species as a cosmetic ingredient in a s...

    Authors: Ruei-Ting Wang, Jui-Hung Yen, Yi-Chi Liao, Yi-Zhen Li and Wei-Ping Wang
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:26
    Content type: Research Published on:

  14. Enhancement of lipid accumulation is the major strategy to improve the commercial feasibility of microalgae as a source for biodiesel production. Pseudochlorella pringsheimii (Formally was named as Chlorella elli...

    Authors: Hanaa Abd El Baky and Gamal El Baroty
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:25
    Content type: Research Published on:

  15. Biopolymers like polyhydroxyalkanoates (PHA) are the best natural macromolecules to use as alternative to the synthetic polymers. Many prokaryotes accumulate PHA as cytoplasmic intracellular granules and their...

    Authors: Teja Mandragutti and G. Sudhakar
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:24
    Content type: Research Published on:

  16. The biopharmaceutical industry is significantly growing worldwide, and the Chinese hamster ovary (CHO) cells are used as a main expression host for the production of recombinant monoclonal antibodies. Various ...

    Authors: V. A. Toporova, V. V. Argentova, T. K. Aliev, A. A. Panina, D. A. Dolgikh and M. P. Kirpichnikov
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:23
    Content type: Research Published on:

  17. Invertebrates like crabs employ their own immune systems to fight against a number of invasive infections. Anti-lipopolysaccharide factors (ALFs) are an important class of antimicrobial peptides (AMPs) exhibit...

    Authors: M. V. Anju, K. Archana, V. V. Anooja, P. P. Athira, S. Neelima, I. S. Bright Singh and Rosamma Philip
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:22
    Content type: Research Published on:

  18. Superoxide dismutase is an important antioxidative stress enzyme which is found in honeybee venom and has a wide pharmaceutical and medical applications.

    Authors: Mohamed M. Abdel-Monsef, Doaa A. Darwish, Hind A. Zidan, Ahmed A. Hamed and Mahmoud A. Ibrahim
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:21
    Content type: Research Published on:

  19. Canine parvovirus (CPV) is a small virus without an envelope that consists of three viral proteins including VP1, VP2, and VP3. Exclusively, the VP2 can form a typically CPV-sized virus-like particle (CPV-VLP)...

    Authors: Mohammad Sadegh Hashemzadeh and Nariman Gharari
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:20
    Content type: Research Published on:

  20. Bone morphogenetic protein receptor 1B (BMPR1B) gene is one of candidate genes for reproductive and growth traits in sheep. The present study was aimed to detect the Booroola (FecB) allele in BMPR1B gene and its ...

    Authors: Endang Tri Margawati, Widya Pintaka Bayu Putra, Muhammad Rizki, Edi Soetrisno and Herman Willem Raadsma
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:19
    Content type: Research Published on:

  21. Marine bacteria have recently attracted increasing attention to be harnessed for the production of valuable enzymes, vitamins, and bioactive compounds. Bacteria associated with the surfaces of marine macroalga...

    Authors: Stalis Norma Ethica, Dewi Seswita Zilda, Oedjijono Oedjijono, Muhtadi Muhtadi, Gintung Patantis, Sri Darmawati, Sri Sinto Dewi, Agus Sabdono and Agustinus Robert Uria
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:18
    Content type: Research Published on:

  22. Applying microbial biostimulants during crop cultivation allows for higher sustainability levels. It reduces the need for fertilizers and environmental contaminants while enhancing plant quality. This study as...

    Authors: Amr M. Mowafy, Sherouk Khalifa and Ashraf Elsayed
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:17
    Content type: Research Published on:

  23. There is always a need for a safe and efficient vaccine platform, especially when facing a pandemic such as COVID-19. Most of the SARS-CoV-2-based vaccines are based on the full spike protein, which is present...

    Authors: Mohamed A. Wahba, Dina Mofed, Doaa A. Ghareeb, Jihad I. Omran and Tamer Z. Salem
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:16
    Content type: Research Published on:

  24. Breadfruit (Artocarpus spp.) is the main genus of Moraceae with multipurpose benefits, both ecologically and economically important, e.g., food ingredients, building materials, traditional medicine, and natural i...

    Authors: Dindin Hidayatul Mursyidin and Akbar Setiawan
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:15
    Content type: Research Published on:

  25. Flavonoid natural dyes have gained attention because they are nontoxic and eco-friendly. However, they do not work effectively with artificial fibers and require the use of mordants, which are considered as ha...

    Authors: Yasmin M. Elsaba, Heba M. El-Hennawi, Mona M. Ibrahim and Hala R. Wehaidy
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:14
    Content type: Research Published on:

  26. NAFLD is one of the fast-growing health problems that affects up to 25% of people worldwide. Numerous miRNAs have been clarified as important regulators of liver pathophysiology, including NAFLD. Thus, we inve...

    Authors: Halla M. Ragab, Wafaa M. Ezzat, Eman Mahmoud Hassan, Nabila Abd El Maksoud, Mie Afify, Mohamed D. E. Abd El-Maksoud and Wafaa Abd Elaziz
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:13
    Content type: Research Published on:

  27. Carbohydrates are known as the main natural products of life activities.

    Authors: Sahar Saleh Mohamed, Mohamed E. El Awady, Sayeda Abdelrazek Abdelhamid, Ahmed Abdelghani Hamed, Abeer A. A. Salama and Manal S. Selim
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:12
    Content type: Research Published on:

  28. Mating elicits significant changes in gene expression and leads to subsequent physiological and behavioural modifications in insects. The reproductive success of both sexes is contributed immensely by the male...

    Authors: R. Mamtha, Tannavi Kiran, Vivek Chandramohan, B. S. Gowrishankar and D. Manjulakumari
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:11
    Content type: Research Published on:

  29. In today’s society, cancer has become a big concern. The most common cancers in women are breast cancer (BC), endometrial cancer (EC), ovarian cancer (OC), and cervical cancer (CC). CC is a type of cervix canc...

    Authors: Md. Tanvir Hasan, Md. Rakibul Islam, Md. Rezwan Islam, Baraa Riyadh Altahan, Kawsar Ahmed, Francis M. Bui, Sami Azam and Mohammad Ali Moni
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:10
    Content type: Research Published on:

  30. Cisplatin resistance is one of the major contributors to the poor survival rate among head and neck cancer (HNC) patients. Focusing on the protein–protein interaction rather than a single protein could provide...

    Authors: Raushan Kumar Chaudhary, Pukar Khanal, Uday Venkat Mateti, C. S. Shastry and Jayarama Shetty
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:9
    Content type: Research Published on:

  31. Cadmium is a non-essential, third largest heavy metal contaminant with long retention time that poses environmental hazards. It emanating majorly from industrial processes and phosphate fertilizers. Cadmium is...

    Authors: Chinreddy Subramanyam Reddy, Min Cho, Tanushri Kaul, Jin Tae Joeng and Kang Min Kim
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:8
    Content type: Research Published on:

  32. Thrombin is the most important enzyme in the hemostatic process by permitting rapid and localized coagulation in case of tissue damage. Camel thrombin is the natural and proper target enzyme for the previously...

    Authors: Mahmoud A. Ibrahim and Hassan M. M. Masoud
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:7
    Content type: Research Published on:

  33. Rg3-ginsenoside, a protopanaxadiol saponin, is a well-known adaptogen used for the prevention of cancer and inflammation. However, despite its distinct biological activity, the concentration of Rg3 in the tota...

    Authors: Zuneera Marium, Muhammad Zubair Siddiqi, Ji-Hye Lee, Wan-Taek Im and Seong-Gu Hwang
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:6
    Content type: Research Published on:

  34. Sucrose non-fermenting-1 (SNF1)-related protein kinase 2 (SnRK2), a plant-specific serine/threonine kinase family, is associated with metabolic responses, including abscisic acid signaling under biotic and abi...

    Authors: Borhan Ahmed, Fakhrul Hasan, Anika Tabassum, Rasel Ahmed, Rajnee Hassan, Md. Ruhul Amin and Mobashwer Alam
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:5
    Content type: Research Published on:

  35. Ziziphus species particularly Ziziphus mauritiana and Ziziphus nummularia constitute an important part of genetic resources in India. They contribute economically as a fruit crop with lots of morphological and po...

    Authors: Amit Sareen, Vikas Sharma and Raghbir Chand Gupta
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:4
    Content type: Research Published on:

  36. CRISPR/Cas9 is the most powerful and versatile genome-editing tool that permits multiplexed-targeted gene modifications for the genetic enhancement of oil palm. Multiplex genome-editing has recently been devel...

    Authors: Bohari Bahariah, Mat Yunus Abdul Masani, Md Piji Mohd Al Akmarul Fizree, Omar Abd Rasid and Ghulam Kadir Ahmad Parveez
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:3
    Content type: Research Published on:

  37. Angina pectoris (AP) occurs when oxygen and other nutrients are insufficient to meet the metabolic needs of the heart muscle. Stable angina is the most common, while the unstable angina is less frequent. Tumor...

    Authors: Shaimaa Y. Abdulfattah and Farah Thamer Samawi
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:2
    Content type: Research Published on:

  38. Cynopterus brachyotis (Müller 1838) is a generalist and widespread fruit bat species which inhabits different types of habitats in Southeast Asia. This species plays an essential role as a seed disperser and poll...

    Authors: Husni Mubarok, Niken Satuti Nur Handayani, Ibnu Maryanto and Tuty Arisuryanti
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:1
    Content type: Research Published on:

  39. Low-temperature expression of recombinant proteins may be advantageous to support their proper folding and preserve bioactivity. The generation of expression vectors regulated under cold conditions can improve...

    Authors: Yaneth Bartolo-Aguilar, Cipriano Chávez-Cabrera, Luis Bernardo Flores-Cotera, Jesús Agustín Badillo-Corona, Carmen Oliver-Salvador and Rodolfo Marsch
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:173
    Content type: Review Published on:

  40. The spread of HIV is on the rise and has become a global issue, especially for underdeveloped and developing countries. This is due to the fact that HIV majorly occurs asymptomatically and is implausible for e...

    Authors: Jyotsna Jai, Deborah Shirleen, Christian Hanbali, Pamela Wijaya, Theresia Brigita Anginan, William Husada and Muhammad Yogi Pratama
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:172
    Content type: Review Published on:

  41. Endophytes are a rich source of novel, distinct, and applicable compounds of interest in agricultural, medical, cosmetic, and pharmaceutical industries. In this respect, they have been attracting growing inter...

    Authors: Siphiwe G. Mahlangu and Siew L. Tai
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:171
    Content type: Research Published on:

  42. Mondia whitei root is often used in Africa as a local therapeutic agent for libido enhancement. The fractions of the M. whitei leaves (MWL) lack chemical characterization of their bioactive components and possibl...

    Authors: Hope Onohuean, Fanny Eseohe Onohuean, Sharon Iyobor Igbinoba, Joseph Obiezu Chukwujekwu Ezeonwumelu, Peter Chinedu Agu, Josiah Eseoghene Ifie, Tusubira Deusdedit and Patrick Maduabuchi Aja
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:170
    Content type: Research Published on:

  43. Arylacetamide deacetylase (AADAC) is a lipolytic enzyme involved in xenobiotic metabolism. The characterization in terms of activity and substrate preference has been limited to a few mammalian species. The po...

    Authors: Tania Diaz-Vidal, Christian Berenice Romero-Olivas and Raúl Balam Martínez-Pérez
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:169
    Content type: Research Published on:

  44. Natural dyes are present in living organisms such as animals and plants and microorganisms such as fungi, bacteria, algae, and yeast. Pigments are fast and easy growth by using cheap components and do not effe...

    Authors: Nesma A. Hemeda, Ghada E. Hegazy, Soad A. Abdelgalil, Nadia A. Soliman, Dina I. Abdel-Meguid and Samy A. El-Assar
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:168
    Content type: Research Published on:

  45. Several species in Lactobacillaceae family were recognized as potential probiotic bacteria. In this group of lactic acid bacteria, species are taxonomically closed and usually share similar 16S rRNA gene, thus, i...

    Authors: Nora Laref and Khadidja Belkheir
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:167
    Content type: Research Published on:

  46. A useful technique for growing large amounts of plant material is in vitro propagation of important medicinal plants. The present investigation deals with the enhancement of secondary metabolite production via...

    Authors: Asmaa M. Khalifa, Eman Abd-ElShafy, Rasha Abu-Khudir and Reda M. Gaafar
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:166
    Content type: Research Published on:

  47. Mass propagation of date palm has attracted the interest of commercial producers. However, this technique still faces many obstacles that hinder production. This study investigated the effect of chitosan (CHT)...

    Authors: Ahmed Madi Waheed Al-Mayahi
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:165
    Content type: Research Published on:

  48. Homocystinuria is an inherited, inborn error of homocysteine metabolism, which leads to the abnormal accumulation of homocysteine and its metabolites in blood and urine, resulting in various complications. Var...

    Authors: Nadeesha Samarasinghe, Dinithi Mahaliyanage, Sumadee De Silva, Eresha Jasinge, Nimal Punyasiri and H. W. Dilanthi
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:164
    Content type: Research Published on:

  49. Ryegrass is a promising crop for the development of meadow farming in the world. More than 1000 cultivated varieties widely used in feed production have been developed, based on the main species — perennial ry...

    Authors: Yulian Mavlyutov, Sergey Kostenko, Anastasia Shamustakimova and Irina Klimenko
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:163
    Content type: Research Published on:

  50. The Himalayas have always been an enigma and, being biodiversity hotspots, are considered extremely important from an ecological point of view. Recent advances in studies regarding high-altitude lakes have gar...

    Authors: Aditi Rai, Shyama Prasad Saha, Toral Manvar and Arindam Bhattacharjee
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:162
    Content type: Research Published on:
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  • ISSN: 2090-5920 (electronic)