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Journal of Genetic Engineering and Biotechnology
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  1. Penicillin G amidase/acylases from microbial sources is a unique enzyme that belongs to the N-terminal nucleophilic hydrolase structural superfamily. It catalyzes the selective hydrolysis of side chain amide/a...

    Authors: Krishika Sambyal and Rahul Vikram Singh

    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:156

    Content type: Review

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  2. Difficult to express peptides are usually produced by co-expression with fusion partners. In this case, a significant mass part of the recombinant product falls on the subsequently removed fusion partner. On t...

    Authors: Murad Mollaev, Artur Zabolotskii, Neonila Gorokhovets, Elena Nikolskaya, Maria Sokol, Andrey Tsedilin, Mariia Mollaeva, Margarita Chirkina, Timofey Kuvaev, Anna Pshenichnikova and Nikita Yabbarov

    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:155

    Content type: Research

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  3. Hepatitis E is a liver disease caused by the pathogen hepatitis E virus (HEV). The largest polyprotein open reading frame 1 (ORF1) contains a nonstructural Y-domain region (YDR) whose activity in HEV adaptatio...

    Authors: Zoya Shafat, Anwar Ahmed, Mohammad K. Parvez and Shama Parveen

    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:154

    Content type: Research

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  4. Mastitis is one of the major diseases causing economic loss to the dairy industry by reducing the quantity and quality of milk. Thus, the objective of this scientific study was to find new biomarkers based on ...

    Authors: Farmanullah Farmanullah, Xianwei Liang, Faheem Ahmed Khan, Mohammad Salim, Zia ur Rehman, Momen Khan, Hira Sajjad Talpur, N. M. Schreurs, Mostafa Gouda, Sami Ullah Khan and Zhang Shujun

    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:153

    Content type: Research

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  5. Mining for precious metals is detrimental to the composition of soil structure and microbial diversity distribution and is a health risk to human communities around the affected communities. This study was aim...

    Authors: U. B. Ibrahim, A. H. Kawo, I. Yusuf and S. Yahaya

    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:152

    Content type: Research

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  6. To develop new breeding technology to improve the breeding ability of bovine, it is the development trend to find the main reason for the occurrence of atresia in these organisms. Transcriptomes of small (100–...

    Authors: Khairy Mohamed Zoheir, Ahmed Mohamed Darwish, Yang Liguo and Abdelkader E. Ashour

    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:151

    Content type: Research

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  7. Impact of interleukin 28B (IL28B) rs12979860 polymorphism on response to direct-acting antivirals agents in HCV genotype 4-infected patients is under investigation. Zinc may have an advantage in improvement of li...

    Authors: Abdelfattah M. Attallah, Dalia Omran, Mohamed A. Abdelrazek, Mohamed Hassany, Sameh Saif, Aza Farid, Riham El Essawey, Muhammad Abdel Ghaffar, Marwa Aabdelghany and Ayman Yosry

    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:150

    Content type: Research

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  8. Soil pollution by heavy metals increases the bioavailability of metals like hexavalent chromium (Cr (VI)), subsequently limiting plant growth and reducing the efficiency of phytoremediation. Plant growth-promo...

    Authors: Nabil Tirry, Aziza Kouchou, Bouchra El Omari, Mohamed Ferioun and Naïma El Ghachtouli

    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:149

    Content type: Research

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  10. Metabolic syndrome is defined as a group of interrelated biochemical, clinical, and metabolic factors that directly increase the risk of cardiovascular disease, obesity, and type 2 diabetes mellitus. MicroRNA-...

    Authors: Miral M. Refeat, Naglaa Abu-Mandil Hassan, Inass Hassan Ahmad, Eman Roshdy Mohamed Mostafa and Khalda S. Amr

    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:147

    Content type: Research

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  11. Chromobacterium species, through their bioactive molecules, help in combating biotic and abiotic stresses in plants and humans. The present study was aimed to identify, characterize and preserve in natural gums t...

    Authors: Sushil K. Sharma, Rakhi Dhyani, Ees Ahmad, Pankaj K. Maurya, Madhu Yadav, Ramesh Chandra Yadav, Vinod Kumar Yadav, Pawan K. Sharma, Mahaveer P. Sharma, Aketi Ramesh and Anil K. Saxena

    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:146

    Content type: Research

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  12. Potato (Solanum tuberosum L.) is one of the most important food crops in the world. Pathogens remain as one of the major constraints limiting potato productivity. Thus, understanding of gene regulation mechanism ...

    Authors: Atnafu Kebede and Mulugeta Kebede

    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:145

    Content type: Research

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  13. Rosa damascena Mill is a well-known species of the rose family. It is famous for its essential oil content. The aim of the present study was to assess the genetic diversity and population structure of a mini core...

    Authors: Atefeh Sadat Mostafavi, Mansour Omidi, Reza Azizinezhad, Alireza Etminan and Hassanali Naghdi Badi

    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:144

    Content type: Research

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  14. Hydrolysis of cellulose-based biomass by cellulases produce fermented sugar for making biofuels, such as bioethanol. Cellulases hydrolyze the β-1,4-glycosidic linkage of cellulose and can be obtained from cult...

    Authors: Rahmat Eko Sanjaya, Kartika Dwi Asni Putri, Anita Kurniati, Ali Rohman and Ni Nyoman Tri Puspaningsih

    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:143

    Content type: Research

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  15. Mung bean is a pulse crop principally grown in the tropic and subtropic parts of the world for its nutrient-rich seeds. Seven mung beans accessions from Eastern Kenya were evaluated using thirteen phenotypic t...

    Authors: Jedidah Wangari Mwangi, Oduor Richard Okoth, Muchemi Peterson Kariuki and Ngugi Mathew Piero

    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:142

    Content type: Research

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  16. Livin/BIRC7 is a member of the inhibitors of apoptosis proteins family which are implicated in development of cancer through the inhibition of apoptosis process. This case-control study was intended to investigat...

    Authors: Basma K. Elmekkawy, Rasha M. S. Shoaib, Amal K. Seleem, Dalia Shalaan and Entsar A. Saad

    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:141

    Content type: Research

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  17. Bacterial biofilms are aggregation or collection of different bacterial cells which are covered by self-produced extracellular matrix and are attached to a substratum. Generally, under stress or in unfavorable...

    Authors: Shivani Singh, Saptashwa Datta, Kannan Badri Narayanan and K. Narayanan Rajnish

    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:140

    Content type: Review

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  18. Cardiovascular disease (CVD) remains the major cause of death worldwide. Most CVD can be prevented by addressing risk factors. Acute myocardial infarction (AMI) is an inflammatory disorder characterized by cha...

    Authors: Ingy M. Hashad, Habiba Nosseir, Gamal M. Shaban, Mohamed F. Abdel Rahman and Mohamed Z. Gad

    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:139

    Content type: Research

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  19. As the body of scientific research focusing on the severe acute respiratory syndrome coronavirus 2 or SARS-CoV-2 continues to grow, several mutations have been reported as very common across the globe. In this...

    Authors: Syeda Tasnim Quayum and Saam Hasan

    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:138

    Content type: Short Communications

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  20. This work investigates the production of citric acid from cashew apple juice, an abundant waste in the processing of cashew, using a local strain of Aspergillus niger and the application of the citric acid as a c...

    Authors: Adekunle Olusegun Adeoye and Agbaje Lateef

    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:137

    Content type: Research

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  21. The present study reports metagenomic sequencing and microbial diversity analysis of the sediment samples of a semi-intensive penaeid shrimp culture system. 16S rRNA gene-based high-throughput sequencing revea...

    Authors: M. S. Chithira, P. V. Aishwarya, Anjali S. Mohan and Swapna P. Antony

    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:136

    Content type: Short Communications

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  22. Protoplasts (i.e., naked plant cells) can be used for in vitro manipulations and genetic improvement in cultivars with economic value. During the last decade, protoplast research in economic brown algae has be...

    Authors: Jose Avila-Peltroche, Boo Yeon Won and Tae Oh Cho

    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:135

    Content type: Research

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  23. The recent recovery of Gyrinops walla as a potential producer of market-quality agarwood in mature damaged woods and branches has led to the intense illicit felling and exportation of G. walla leading to the verg...

    Authors: Sachithri Munasinghe, Seneviratnege Somaratne, Shyama Weerakoon and Chandani Ranasinghe

    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:134

    Content type: Research

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  24. Amoebiasis, being endemic worldwide, is the second leading cause of parasite-associated morbidity and mortality after malaria. The human parasite Entamoeba histolytica is responsible for the disease. Metronidazol...

    Authors: Suchetana Pal, Pinaki Biswas, Raktim Ghosh and Somasri Dam

    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:133

    Content type: Research

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  25. Vitiligo is a common pigmentary disorder in which autoimmunity has been suggested to play an important role. Toll-like receptor (TLR) family are recognized different molecular structures expressed on immune ce...

    Authors: Maha Abdelsalam, Sherihan H. Allam, Marwa Zohdy, Hend Magdy and Maged Mostafa

    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:132

    Content type: Research

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  26. The aim of this work was to synthesize copper oxide nanoparticles (CuO NPs) utilizing heartwood aqueous extract of Suaeda maritima (L.) Dumort. The synthesis of CuO NPs using green methodology with small size and...

    Authors: Pavani Peddi, Prasada Rao PTSRK, Nannapaneni Usha Rani and S. Lakshmi Tulasi

    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:131

    Content type: Research

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  27. In resource-limited countries, ABO, HLA, MNS, Kells, and hemoglobin electrophoresis are classic tests for the resolution of paternity disputes due to their affordable cost. The limitations of these tests in ca...

    Authors: Missa Millogo, Serge Theophile Soubeiga, Bapio Valerie Jean Telesphore Bazie, Theodora Mahoukede Zohoncon, Abdoul Karim Ouattara, Albert Theophane Yonli and Jacques Simpore

    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:130

    Content type: Research

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  29. DNA markers improved the productivity and accuracy of classical plant breeding by means of marker-assisted selection (MAS). The enormous number of quantitative trait loci (QTLs) mapping read for different plan...

    Authors: Nazarul Hasan, Sana Choudhary, Neha Naaz, Nidhi Sharma and Rafiul Amin Laskar

    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:128

    Content type: Review

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  30. Tuta absoluta Meyrick 1917 (Lepidoptera: Gelechiidae) is an invasive, pesticide resistant, and a major treat of tomato production in the world. It needs effective management options that naturally infect the inse...

    Authors: Birhan Aynalem, Diriba Muleta, Juan Venegas and Fassil Assefa

    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:127

    Content type: Research

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  31. Nanoparticle synthesis is a very interesting area of research currently due to the wide applications of nanoparticles. The nanoparticles have a diameter ranging between 1 and 100 nm and they are used in differ...

    Authors: Deeksha Chugh, V. S. Viswamalya and Bannhi Das

    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:126

    Content type: Review

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  32. Genome of an organism has always fascinated life scientists. With the discovery of restriction endonucleases, scientists were able to make targeted manipulations (knockouts) in any gene sequence of any organis...

    Authors: Anuradha Bhardwaj and Vikrant Nain

    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:125

    Content type: Review

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  33. Phospholipases hydrolyze glycerophospholipids and generate diverse lipid-derived molecules with secondary messenger activity. Out of these, phospholipase C (PLC) specifically cleaves the phospholipids at ester...

    Authors: Madhvi Kanchan, Thakku R. Ramkumar, Himani and Jaspreet K. Sembi

    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:124

    Content type: Research

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  34. γ-Aminobutyric acid sub-type A receptors (GABAARs) are the most prominent inhibitory neurotransmitter receptors in the CNS. They are a family of ligand-gated ion channel with significant physiological and therape...

    Authors: Amr Ghit, Dina Assal, Ahmed S. Al-Shami and Diaa Eldin E. Hussein

    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:123

    Content type: Review

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  35. Terrestrial orchids belonging to the Orchis genus are difficult to propagate and are under great pressure in their natural habitats. Studies regarding the influence of photoperiod and temperature regimes on Orchi...

    Authors: Aleksandra Yurievna Nabieva

    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:122

    Content type: Research

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  36. Canine circovirus is a deadly pathogen of dogs and causes vasculitis and hemorrhagic enteritis. It causes lethal gastroenteritis in pigs, fox, and dogs. Canine circovirus genome contains two main (and opposite) t...

    Authors: Pankaj Jain, Amit Joshi, Nahid Akhtar, Sunil Krishnan and Vikas Kaushik

    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:121

    Content type: Research

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  37. The present study dealt with the screening of soil bacteria with antibacterial activity from different locations in Bangalore, India. Antibiotics play the role of self-defense mechanism for the bacteria and ar...

    Authors: R. Prashanthi, Shreevatsa G.K., Krupalini S. and Manoj L.

    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:120

    Content type: Research

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  38. Sandwich ELISA is an ideal antigen detection and quantification assay. Recently, it was used as the basic concept for high technology diagnostics. The specificity of the assay depends on the exclusion of detec...

    Authors: Rola Nadeem, Ahmed B. Barakat and Mahmoud M. Bahgat

    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:119

    Content type: Research

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  39. Illicium griffithii is an aromatic medicinal tree species that has been listed in the IUCN Red List as an endangered species. Dried seed pods of I. griffithii have a good market potential in the spices and pharma...

    Authors: Rajib Borah, Atanu Bhattacharjee, Satyawada Rama Rao, Vineet Kumar, Pradeep Sharma, Krishna Upadhaya and Hiranjit Choudhury

    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:118

    Content type: Research

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  40. Oleuropein, the main bitter phenolic glucoside responsible for green olive bitterness, may be degraded by the β-glucosidase enzyme to release glucose and phenolic compounds.

    Authors: Yahya Rokni, Houssam Abouloifa, Reda Bellaouchi, Ismail Hasnaoui, Sara Gaamouche, Zahra Lamzira, Riadh B. E. N. Salah, Ennouamane Saalaoui, Nabil Ghabbour and Abdeslam Asehraou

    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:117

    Content type: Research

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  41. Ovarian cancer causes more deaths than any other cancer of the female reproductive system because there is no effective screening and most women are diagnosed at advanced stages. The probability of survival at...

    Authors: J. N. Nikhitha, K. S. Swathy and R. Pratap Chandran

    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:116

    Content type: Research

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  42. Vitamin D receptor (VDR) is known as one of the cellular regulators for several metabolic pathways indicating its pivotal role in the pathological pathway of numerous diseases. Considering the high frequency o...

    Authors: Nayera E. Hassan, Sahar A. El-Masry, Waheba Ahmed Zarouk, Ghada Nour Eldeen, Rehab M. Mosaad, Mahmoud A. S. Afify, Manal M. Aly and Aya Khalil

    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:115

    Content type: Research

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  43. The health-promoting effects along with global economic importance of consuming food products supplemented with probiotic microorganisms encouraged the researchers to discover new probiotics.

    Authors: Al-Shimaa Ibrahim Ahmed, Gihan Mohamed El Moghazy, Tarek Ragab Elsayed, Hanan Abdel Latif Goda and Galal Mahmoud Khalafalla

    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:114

    Content type: Research

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  44. Targeting viral cell entry proteins is an emerging therapeutic strategy for inhibiting the first stage of SARS-CoV-2 infection. In this study, 106 bioactive terpenoids from African medicinal plants were screen...

    Authors: Gideon A. Gyebi, Oludare M. Ogunyemi, Ibrahim M. Ibrahim, Olalekan B. Ogunro, Adegbenro P. Adegunloye and Saheed O. Afolabi

    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:113

    Content type: Research

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  45. Variants in the signal transducer and activator of transcription 4 (STAT4) gene have an important role in the incident of multiple autoimmune diseases including type 1 diabetes mellitus (T1D). It is a genetica...

    Authors: Samar Samir Abdelmajed, Mohamed A. El-Dessouky, Doaa S. SalahElDin, Naglaa Abu-Mandil Hassan, Moushira Erfan Zaki and Somaia Ismail

    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:112

    Content type: Research

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  46. Mucolipidosis II (ML II α/β) is an inherited lysosomal storage disorder caused by deficiency of GlcNAc-phosphotransferase enzyme and results in mis-targeting of multiple lysosomal enzymes. Affected patients ar...

    Authors: Mona L. Essawi, Ekram M. Fateen, Hanan A. Atia, Noura R. Eissa, Eman H. Aboul-Ezz, Mona M. Ibrahim, Heba A. Hassan and Samia A. Temtamy

    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:111

    Content type: Research

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  47. Pullulanases are the significant industrial group in the 13 glycosyl hydrolases category, known as the α-amylases family. There are very few reports on pullulanase from fungal sources. Based on the above resea...

    Authors: Bindu Naik, S. K. Goyal, Abhishek Dutt Tripathi and Vijay Kumar

    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:110

    Content type: Research

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  48. Insulin-like growth factor-1 (IGF-1) is required for normal intrauterine and postnatal growth, and this action is mediated through IGF1 receptor (IGF1R). IGF1R copy number variants (CNVs) can cause pre- and postn...

    Authors: Islam M. Fadel, Moustafa H. Ragab, Ola M. Eid, Nivine A. Helmy, Hala T. El-Bassyouni and Inas Mazen

    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:109

    Content type: Research

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  49. Anarrhinum pubescens Fresen. (Plantaginaceae) is a rare plant, endemic to the Saint Catherine area, of South Sinai, Egypt. Earlier studies have reported the isolation of cytotoxic and anti-cholinesterase iridoid ...

    Authors: Asmaa Abdelsalam, Ehab Mahran, Kamal Chowdhury and Arezue Boroujerdi

    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:108

    Content type: Research

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  50. Argentina’s geothermal areas are niches of a rich microbial diversity. In 2020, species of Bacillus cytotoxicus were isolated for the first time from these types of pristine natural areas. Bacillus cytotoxicus st...

    Authors: Ivana Cavello, Brenda Bezus and Sebastián Cavalitto

    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:107

    Content type: Research

    Published on:

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  • ISSN: 2090-5920 (electronic)