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Journal of Genetic Engineering and Biotechnology
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  1. The bark of Casuarina equisetifolia contains several active phytoconstituents that are suitable for the biosynthesis of gold nanoparticles (Au-NPs). These nanoparticles were subsequently evaluated for their effec...

    Authors: Wael Mahmoud Aboulthana, Noha El-Sayed Ibrahim, Amgad Kamal Hassan, Wagdy Khalil Bassaly, Hassan Abdel-Gawad, Hamdy Ahmed Taha and Kawkab A. Ahmed
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:158
    Content type: Research Published on:

  2. Lipases have emerged as essential biocatalysts, having the ability to contribute to a wide range of industrial applications. Microbial lipases have garnered significant industrial attention due to their stabil...

    Authors: Naswandi Nur, Antonius Suwanto, Anja Meryandini, Maggy Thenawidjaja Suhartono, Esti Puspitasari and Hyung Kwoun Kim
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:157
    Content type: Research Published on:

  3. This article provides an overview of microbial host selection, synthetic biology, genome annotation, metabolic modeling, and computational methods for predicting gene essentiality for developing a microbial ch...

    Authors: Saltiel Hamese, Kanganwiro Mugwanda, Mutsa Takundwa, Earl Prinsloo and Deepak B. Thimiri Govinda Raj
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:156
    Content type: Review Published on:

  4. World Health Organization recommend the use of malaria vaccine, Mosquirix, as a malaria prevention strategy. However, Mosquirix has failed to reduce the global burden of malaria because of its inefficacy. The ...

    Authors: Okello Harrison Onyango, Cynthia Mugo Mwenda, Grace Gitau, John Muoma and Patrick Okoth
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:155
    Content type: Research Published on:

  5. Vaccination is a crucial tool in preventing influenza, but it requires annual updates in vaccine composition due to the ever-changing nature of the flu virus. While healthcare and economic burdens have reduced...

    Authors: Dipanshi Gupta and Sumedha Mohan
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:154
    Content type: Review Published on:

  6. The worldwide increase in human population and environmental damage has put immense pressure on the overall global crop production making it inadequate to feed the entire population. Therefore, the need for su...

    Authors: Soma Biswas, Indhu Philip, Saranya Jayaram and Suma Sarojini
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:153
    Content type: Research Published on:

  7. Brucellosis caused by B. melitensis is one of the most important common diseases between humans and livestock. Currently, live attenuated vaccines are used for this disease, which causes many problems, and unfort...

    Authors: Pejman Hashemzadeh, Saba Asgari nezhad and Hossein Khoshkhabar
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:152
    Content type: Research Published on:

  8. Cellulase is an important bioprocessing enzyme used in various industries. This study was conducted with the aim of improving the biodegradation activity of cellulase obtained from the Bacillus subtilis AG-PQ str...

    Authors: Saddam Hussain, Muhammad Talha Yasin, Khurshid Ahmad, Suleman Khan, Rasheed Ahmad, Jallat Khan, Abdul Ghani, Muhammad Musaddiq Shah, Muzzamil Ahmed, Hasnat Tariq, Hamid Rehman, Adil Hussain, Muhammad Faheem and Syed Ali Imran Bokhari
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:151
    Content type: Research Published on:

  9. Aplastic anemia (AA) is a bone marrow disorder characterized by peripheral pancytopenia and marrow hypoplasia which can lead to life-threatening complications. Our objective was to study the telomerase genes (TER...

    Authors: Mona F. Sokkar, Mona Hamdy, Peter SF Erian, Rehab M. Mosaad, Nesma M. Elaraby, Mohamed B. Taher, Heba El-Sayed, Mohammed Al Komy, Maha M. Eid, Amal M. Mohamed, Khalda S. Amr and Ghada Y. El-Kamah
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:149
    Content type: Research Published on:

  10. Factorial design is a simple, yet elegant method to investigate the effect of multiple factors and their interaction on a specific response simultaneously. Hence, this type of study design reaches the best opt...

    Authors: Najla Alotaibi, Alia Aldahlawi, Kawther Zaher, Fatemah Basingab and Jehan Alrahimi
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:144
    Content type: Research Published on:

  11. The ability of actinomycetes to produce bioactive secondary metabolites makes them one of the most important prokaryotes. Marine actinomycetes are one of the most important secondary metabolites producers used...

    Authors: Ghada E. Hegazy, Zakia A. Olama, G. M. Abou-Elela, Heba S. Ramadan, Walaa M. Ibrahim and Dalia El S. El Badan
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:150
    Content type: Research Published on:

  12. The ongoing concern surrounding coronavirus disease 2019 (COVID-19) primarily stems from continuous mutations in the genome of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), leading to the e...

    Authors: Sofia Safitri Hessel, Fenny Martha Dwivany, Ima Mulyama Zainuddin, Ketut Wikantika, Ismail Celik, Talha Bin Emran and Trina Ekawati Tallei
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:148
    Content type: Research Published on:

  13. The health index of any population is directly correlated with the water quality, which in turn depends upon physicochemical characteristics and the microbiome of that aquatic source. For maintaining the water...

    Authors: Bhavna Brar, Ravi Kumar, Dixit Sharma, Amit Kumar Sharma, Kushal Thakur, Danish Mahajan and Rakesh Kumar
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:147
    Content type: Research Published on:

  14. Members of Enterobacteriaceae such as Escherichia coli O 157:H7, Salmonella sp., Shigella sp., Klebsiella sp., and Citrobacter freundii are responsible for the outbreak of serious foodborne illness and other muco...

    Authors: Harish Babu Kolla, Shivakiran Satyanarayan Makam and Prakash Narayana Reddy
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:146
    Content type: Research Published on:

  15. Viral infections cause damage and long-term injury to infected human tissues, demanding therapy with antiviral and wound healing medications. Consequently, safe phytochemical molecules that may control viral i...

    Authors: Ahmed Mostafa, Gomaa Mostafa-Hedeab, Hany Abdelfattah Elhady, Esraa Ahmed Mohamed, Abozer Y. Eledrdery, Sager Holyl Alruwaili, Ahmed Mohamed Al-Abd and Abdou Kamal Allayeh
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:145
    Content type: Research Published on:

  16. Marburg virus (MARV) is a member of the Filoviridae family and causes Marburg virus disease (MVD) among humans and primates. With fatality rates going up to 88%, there is currently no commercialized cure or va...

    Authors: Bishal Debroy, Sribas Chowdhury and Kuntal Pal
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:143
    Content type: Research Published on:

  17. Phytase supplementation in rations can reduce their phytic acid composition in order to enhance their nutritional value. Aspergillus niger is a fungus that can encode phytase. This study aims to determine the cha...

    Authors: Hamdan Maulana, Yantyati Widyastuti, Nina Herlina, Abun Hasbuna, Aas Syiarudin Hasbi Al-Islahi, Lita Triratna and Novi Mayasari
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:142
    Content type: Research Published on:

  18. Cholesterol oxidase has numerous biomedical and industrial applications. In the current study, a new bacterial strain was isolated from sewage and was selected for its high potency for cholesterol degradation ...

    Authors: Walid A. Lotfy, Hala M. Badawy, Khaled M. Ghanem and Samy A. El-Aassar
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:141
    Content type: Research Published on:

  19. Microsatellites or simple sequence repeats (SSR) consist of 1–6 nucleotide motifs of DNA or RNA which are ubiquitously present in tandem repeated sequences across genome in viruses: prokaryotes and eukaryotes....

    Authors: Md Gulam Jilani, Mehboob Hoque and Safdar Ali
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:140
    Content type: Research Published on:

  20. The presence of drug-resistant Gram-negative pathogenic bacteria and Extended Spectrum β-Lactamase Producers (ESBLs) in hospital associated fomites like door handles can serve as vehicles in transmission and m...

    Authors: Binita Koirala Sharma, Birendra Prasad Sharma, Anjeela Kunwar, Nirmala Basnet, Padam Darlami Magar and Sajana Adhikari
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:139
    Content type: Research Published on:

  21. Actinomycetes are excellent microbial sources for various chemical structures like enzymes, most of which are used in pharmaceutical and industrial products. Actinomycetes are preferred sources of enzymes due ...

    Authors: Zuhour Hussein Wardah, Hiral G. Chaudhari, Vimalkumar Prajapati and Gopalkumar G. Raol
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:138
    Content type: Research Published on:

  22. Microorganisms have characteristics that aid plant growth and raise the level of vital metabolites in plants for better growth including primary and secondary metabolites as well as several developmental enzym...

    Authors: Khushbu Rathod, Shruti Rana, Pinakin Dhandukia and Janki N. Thakker
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:137
    Content type: Research Published on:

  23. Enzymatic catalysis in different industrial applications is often preferred over chemical methods due to various advantages, such as higher specificity, greater efficiency, and less environmental footprint. Pe...

    Authors: Sabrina Samad Shoily, Kaniz Fatema, Rasheda Begum Dina, Anik Biswas, Papia Haque, Mohammed Mizanur Rahman, Md. Zulhash Uddin and Abu Ashfaqur Sajib
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:136
    Content type: Research Published on:

  24. Staphylococcus aureus is a gram-positive spherical bacteria and the most common cause of nosocomial infections in the world. Given its clinical significance, the genome sequence of S. aureus has been elucidated t...

    Authors: Vivian Chakma, Dhirendra Nath Barman, Shuvo Chandra Das, Anwar Hossain, Monira Binte Momin, Maisha Tasneem and Shipan Das Gupta
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:135
    Content type: Research Published on:

  25. The relationship between nutrition and genes has long been hinted at and sometimes plainly associated with certain diseases. Now, after many years of research and coincidental findings, it is believed that thi...

    Authors: Neemat M. Kassem, Yassmin A. Abdelmegid, Mahmoud K. El-Sayed, Rana S. Sayed, Mahmoud H. Abdel-Aalla and Hebatallah A. Kassem
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:134
    Content type: Review Published on:

  27. Certain Bacillus species play a vital role in polyhydroxyalkanoate (PHA) production. However, most of these isolates did not properly identify to species level when scientifically had been reported.

    Authors: Seid Mohammed Ebu, Lopamudra Ray, Ananta N. Panda and Sudhansu K. Gouda
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:132
    Content type: Research Published on:

  28. Breast cancer is the most significant threat to women worldwide. Most chemotherapeutic drugs cause cancer cell death and apoptosis by inducing oxidative stress and producing reactive oxygen species (ROS). Canc...

    Authors: R. A. Guneidy, E. R. Zaki, G. S. A. Abdel Karim, N. S. Saleh and A. Shokeer
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:131
    Content type: Research Published on:

  29. Antimicrobial peptides (AMPs), innate immune response molecules in organisms, are also known for their dual functionality, exemplified by hepcidin—an immunomodulator and iron regulator. Identifying and studyin...

    Authors: K. L. Dhanya Lenin and Swapna P. Antony
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:130
    Content type: Short Communications Published on:

  30. DNA polymerase is an essential component in PCR assay for DNA synthesis. Improving DNA polymerase with characteristics indispensable for a powerful assay is crucial because it can be used in wide-range applica...

    Authors: Isa Nuryana, Fina Amreta Laksmi, Kartika Sari Dewi, Faiz Raihan Akbar, Nurhayati and Rikno Harmoko
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:129
    Content type: Research Published on:

  31. Immunoinformatics is an emerging interdisciplinary field which integrates immunology, bioinformatics, and computational biology to study the immune system. In this study, we apply immunoinformatics approaches ...

    Authors: Nishat Bano and Ajay Kumar
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:128
    Content type: Research Published on:

  32. At the present time, there is a persistent need to get rid of environmental contaminants by eco-friendly, sustainable, and economical technologies. Uncontrolled disposal practices of domestic and industrial so...

    Authors: Manar A. Basheer, Khaled Abutaleb, Nermine N. Abed and Amal A. I. Mekawey
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:127
    Content type: Research Published on:

  33. Cervical cancer caused by the human papillomavirus (HPV) is one of the most frequent malignances globally. HPV 52 is a high-risk cancer-causing genotype that has been identified as the most prevalent type in I...

    Authors: Chindy Nur Rosmeita, Sri Budiarti, Apon Zaenal Mustopa, Ela Novianti, Sri Swasthikawati, Sheila Chairunnisa, Ai Hertati, Maritsa Nurfatwa, Nurlaili Ekawati and Nurhasni Hasan
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:126
    Content type: Research Published on:

  34. Salmonella Typhi stands as the etiological agent responsible for the onset of human typhoid fever. The pressing demand for innovative therapeutic targets against S. Typhi is underscored by the escalating prevale...

    Authors: Kanwal Khan, Khurshid Jalal and Reaz Uddin
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:125
    Content type: Research Published on:

  35. Early childhood caries is a significant public health concern affecting about 600 million children globally. The etiology of early childhood caries can be explained as an interplay between genetic and environm...

    Authors: P. Aruna, Sneha S. Patil, M. S. Muthu, V. Vettriselvi, Selva Arockiam, R. Kirubakaran and N. Sivakumar
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:124
    Content type: Review Published on:

  36. The specificity of protein functions depends on its folding ability into a functional structure. Protein folding is an essential systemic phenomenon that prevents incorrect folding which could result in harmfu...

    Authors: Babatunde Joseph Oso, Ige Olaoye and Olufunke Temiloluwa Oso
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:123
    Content type: Research Published on:

  37. SMYD2 is a protein of the SET and MYND domain-containing family SMYD. It can methylate the lysine residue of various histone and nonhistone cancer-related proteins and plays a critical role in tumorigenesis. A...

    Authors: Arvind Kumar Yadav and Tiratha Raj Singh
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:122
    Content type: Research Published on:

  38. This paper reports the preparation of a new family of spiked gold nanoparticles, spiked gold nanobipyramids (SNBPs). This protocol includes the process to synthesize gold nanobipyramids (NBPs) using combined s...

    Authors: Phat Trong Huynh, Khanh Thi Le Tran, Tham Thi Hong Nguyen, Vinh Quang Lam, Ngan Thi Kim Phan and Thanh Vo Ke Ngo
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:121
    Content type: Research Published on:

  39. Israel confirmed the first case of “flurona”—a co-infection of seasonal flu (IAV) and SARS-CoV-2 in an unvaccinated pregnant woman. This twindemic has been confirmed in multiple countries and underscores the i...

    Authors: Amir Elalouf, Tomer Kedarya, Hadas Elalouf and Ariel Rosenfeld
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:120
    Content type: Research Published on:

  40. Mutations in GDAP1 (Ganglioside-induced differentiation-associated protein 1) gene are linked to Charcot-Marie-Tooth disease (CMT), a Heterogenous group of disorders with multiple phenotypes, characterized by ...

    Authors: Uzma Manzoor, Awais Ali, S. Luqman Ali, Omneya Abdelkarem, Sumaira Kanwal, Saqer S. Alotaibi, Alaa Baazeem, Aliya Baiduissenova, Ayaz Yktiyarov, Azraida Hajar and Abay Olzhabay
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:119
    Content type: Research Published on:

  41. Banana production is increasingly under threat due to harsh weather conditions as a result of climate change and different diseases. As such there is a need for the preservation and the characterization of the...

    Authors: Kumbirai Beaton, Allen Mazadza and Zedias Chikwambi
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:118
    Content type: Research Published on:

  42. Hepatitis C Virus (HCV) infection is one of the causal agents of liver disease burden. Six multiple antigenic peptides were synthesized including (P315, P412, and P517) plus (P1771, P2121, and P2941) to induce...

    Authors: Ashraf M. Muhammad, Ghada M. Salum, Mai Abd El Meguid, Basma E. Fotouh and Reham M. Dawood
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:117
    Content type: Research Published on:

  43. Bigfin squid is one of the economically important seafood resources in Vietnam’s fisheries and the waters around Con Dao and Phu Quoc islands are two major fishing grounds where this species has been actively ...

    Authors: Le Ngoc Trieu, Thai Thach Bich, Nguyen Van Ket and Nguyen Van Long
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:116
    Content type: Research Published on:

  44. Sanger dideoxy sequencing is vital in clinical analysis due to its accuracy, ability to analyze genetic markers like SNPs and STRs, capability to generate reliable DNA profiles, and its role in resolving compl...

    Authors: Mohammed Baqur S. Al-Shuhaib and Hayder O. Hashim
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:115
    Content type: Review Published on:

  45. The identification of miRNAs as well as characterization of miRNA-mRNA interactions in SARS-CoV-2 infection is important to understand their role in disease pathogenesis. Therefore the aim of the present study...

    Authors: Riham Abdel-Hamid Haroun, Waleed H. Osman and Asmaa M. Eessa
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:114
    Content type: Research Published on:

  46. Asthma is a chronic and complex pulmonary condition that affects the airways. A total of 250,000 asthma-related deaths are recorded annually and several proteins including chymase, spleen tyrosine kinase, and ...

    Authors: Precious Ayorinde Akinnusi, Samuel Olawale Olubode, Ayomide Oluwadarasimi Adebesin, Adebowale Abiodun Alade, Victor Chinedu Nwoke and Sidiqat Adamson Shodehinde
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:113
    Content type: Research Published on:

  47. One of the 11 recognized mucopolysaccharidosis (MPS) diseases is Sanfilippo. It is autosomal recessive in its mode of transmission. There are four subtypes of Sanfilippo (A, B, C, and D). The most worldwide pr...

    Authors: Soha S. Nosier, Seham M. S. El Nakeeb, Mona M. Ibrahim, Mona El-Gammal and Ekram M. Fateen
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:112
    Content type: Research Published on:

  48. The deletions of azoospermic factor regions (AZF) are considered risk factor of spermatogenic failure. AZF duplications or complex copy number variants (CNVs) were rarely studied because STS-PCR could not alwa...

    Authors: Maha M. Eid, Ola M. Eid, Amany H. Abdelrahman, Islam F. S. Abdelrahman, Elshaimaa A. F. Aboelkomsan, Rania M. A. AbdelKader, Mirhane Hassan, Marwa Farid, Alshaymaa A. Ibrahim, Safa N. Abd El-Fattah and Rana Mahrous
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:111
    Content type: Research Published on:

  49. Nitrogen is one of the most important mineral nutrients for plants and is absorbed by the root system mainly in the inorganic form (NH+4 and NO−3). Plants absorb nitrogen as a food source for growth, biomass prod...

    Authors: Zohreh Hajibarat, Abbas Saidi, Habibollah Ghazvini and Zahra Hajibarat
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:110
    Content type: Research Published on:

  50. Obesity is one of the most serious problems over the world. MicroRNAs have developed as main mediators of metabolic processes, playing significant roles in physiological processes. Thus, the present study aime...

    Authors: Weaam Gouda, Amr E. Ahmed, Lamiaa Mageed, Amgad K. Hassan, Mie Afify, W. I. Hamimy, Halla M. Ragab, Nabila Abd El Maksoud, Abdou K. Allayeh and Mohamed D. E. Abdelmaksoud
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:109
    Content type: Research Published on:

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2022 Citation Impact
3.5 - 2-year Impact Factor
1.002 - SNIP (Source Normalized Impact per Paper)
0.560 - SJR (SCImago Journal Rank)

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  • ISSN: 2090-5920 (electronic)