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Journal of Genetic Engineering and Biotechnology
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  1. Vaccination is the one of the agendas of many countries to reduce cervical cancer caused by the Human papillomavirus. Currently, VLP-based vaccine is the most potent vaccine against HPV, which could be produce...

    Authors: Moh Egy Rahman Firdaus, Apon Zaenal Mustopa, Nurlaili Ekawati, Sheila Chairunnisa, Rosyida Khusniatul Arifah, Ai Hertati, Shasmita Irawan, Anika Prastyowati, Arizah Kusumawati and Maritsa Nurfatwa
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:68
    Content type: Research Published on:

  2. Date palm, oasis pivot, plays a vital socio-economic part in the southern area of Morocco. However, with climate change and drought intensity and frequency increasing, the Moroccan palm grove is threatened wit...

    Authors: Maha Ibrahimi, Najiba Brhadda, Rabea Ziri, Mohamed Fokar, Driss Iraqi, Fatima Gaboun, Mustapha Labhilili, Aicha Habach, Reda Meziani, Jamal Elfadile, Rabha Abdelwahd and Ghizlane Diria
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:66
    Content type: Research Published on:

  3. Human insulin was the first FDA-approved biopharmaceutical drug produced through recombinant DNA technology. The previous studies successfully expressed recombinant human insulin precursors (HIP) in Pichia pastor...

    Authors: Nuruliawaty Utami, Dini Nurdiani, Hariyatun Hariyatun, Eko Wahyu Putro, Fadillah Putri Patria and Wien Kusharyoto
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:67
    Content type: Research Published on:

  4. SARS-CoV-2 infection involves disturbing multiple molecular pathways related to immunity and cellular functions. PIM1 is a serine/threonine-protein kinase found to be involved in the pathogenesis of several vi...

    Authors: Magda M. F. Ismail, Rehab R. El-Awady, Amal M. Farrag, Sara H. Mahmoud, Noura M. Abo Shama, Ahmed Mostafa, Mohamed A. Ali, Mohammed H. Rashed and Iman H. Ibrahim
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:65
    Content type: Research Published on:

  5. Arsenic, a ubiquitous toxic metalloid, is a threat to the survival of all living organisms. Bioaccumulation of arsenic interferes with the normal physiological pathway. To overcome arsenic toxicity, organisms ...

    Authors: Ashutosh Kabiraj, Anubhab Laha, Anindya Sundar Panja and Rajib Bandopadhyay
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:64
    Content type: Research Published on:

  6. Over the years, excessive use of chemical pesticides to control plant pathogens has caused environmental problems. Therefore, biological solutions such as the use of microorganisms with antimicrobial capacity ...

    Authors: Pelias Rafanomezantsoa, Samia Gharbi, Noureddine Karkachi and Mebrouk Kihal
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:63
    Content type: Research Published on:

  7. Adeno-associated virus (AAV) vectors have emerged as the leading delivery platforms for gene therapy. Throughout the life cycle of the virions, the capsid vector carries out diverse functions, ranging from cel...

    Authors: Yanqiao Shawn Xiang and Gang Gary Hao
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:62
    Content type: Review Published on:

  8. Calf rennet is considered the traditional source of milk clotting enzyme (MCE). However, increasing cheese consumption with decreasing the calf rennet supply had encouraged the quest for new rennet alternative...

    Authors: Hala R. Wehaidy, Mohamed A. Abdel-Naby, Adel M. M. Kholif, Mostafa Elaaser, Wafaa K. Bahgaat and Walaa A. Abdel Wahab
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:61
    Content type: Research Published on:

  10. Epigenome, genetic variants, and other environmental factors involved in gene regulation are highly inter-dependent in several chronic diseases, including obesity, cardiovascular disease, and diabetes. The pre...

    Authors: Sahar Abdulaziz AlSedairy, Laila Naif Al-Harbi, Manal Abdulaziz Binobead, Jegan Athinarayanan, Shaista Arzoo, Dalia Saade Al-Tamimi, Ghalia Shamlan, Ali Abdullah Alshatwi and Vaiyapuri Subbarayan Periasamy
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:59
    Content type: Research Published on:

  11. Sudangrass (Sorghum sudanense) is a major biomass producer for livestock feed and biofuel in many countries. It has a wide range of adaptations for growing on marginal lands under biotic and abiotic stresses. The...

    Authors: Shireen K. Assem, Mahmoud A. Basry, Taha A. Taha, M. H. Abd El-Aziz, Taher Alwa and Walid M. Fouad
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:58
    Content type: Research Published on:

  12. Streptococcus pneumoniae (SPN) is the agent responsible for causing respiratory diseases, including pneumonia, which causes severe health hazards and child deaths globally. Antibiotics are used to treat SPN as a ...

    Authors: Lincon Mazumder, Muhammad Shahab, Saidul Islam, Mahmuda Begum, Jonas Ivan Nobre Oliveira, Shamima Begum and Shahina Akter
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:57
    Content type: Research Published on:

  13. Garlic (Allium sativum L.) is the second most widely cultivated Allium which is mainly grown in temperate regions and used as a flavoring agent in a wide variety of foods. Garlic contains various bioactive compou...

    Authors: Malyaj R. Prajapati, Jitender Singh, Pankaj Kumar and Rekha Dixit
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:56
    Content type: Short Communications Published on:

  14. Nowadays, breakthroughs in molecular biology are happening at an unprecedented rate. One of them is the ability to engineer transgenic animals. A transgenic animal is one whose genome has been changed to carry...

    Authors: W. M. E. Shakweer, A. Y. Krivoruchko, Sh.M. Dessouki and A. A. Khattab
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:55
    Content type: Review Published on:

  16. MM (multiple myeloma) is a bone marrow disease with the accumulation of malignant plasma cells characterized by the neoplastic transformation of differentiated B cells.

    Authors: Akanksha A. Kalal, Reshma A. Shetty, Akshay Bairapura Manjappa, Nagaraj V. Kulkarni and Prashanth Shetty
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:50
    Content type: Research Published on:

  17. Finding natural products with anticancer activity is an effective strategy to fight this disease. In this respect, Lepidium sativum or garden cress (family Brassicaceae) has been widely used worldwide for its wid...

    Authors: Mona M. Ibrahim, Marwa M. Mounier and Shawky A. Bekheet
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:53
    Content type: Research Published on:

  18. Probiotics are live microorganisms that provide beneficial effects on the host’s health when exploited in adequate amounts. This study aimed at carrying out whole-genome sequence analysis and in vitro potentia...

    Authors: Nshimiyimana Sylvere, Apon Zaenal Mustopa, Sri Budiarti, Lita Meilina, Ai Hertati and Ira Handayani
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:49
    Content type: Research Published on:

  19. Zinc oxide nanoparticles (ZnO NPs) can be considered as nanofertilizer providing zinc as an essential micronutrient for plant growth and production at specific safe dose, however, above this dose; ZnO NPs indu...

    Authors: Doaa E. Elsherif, Eman Abd-ElShafy and Asmaa M. Khalifa
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:52
    Content type: Research Published on:

  20. Eighty-three strains of Leuconostoc mesenteroides were isolated from Algerian raw camel milk. Based on morphological, biochemical, and physiological characters tests, strains were identified as Ln. mesenteroides ...

    Authors: Hanane Fatma Chentouf, Fouzia Rahli, Zineb Benmechernene and Jorge Barros-Velazquez
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:51
    Content type: Research Published on:

  21. Hydrolytic enzymes from halophilic microorganisms have a wide range of industrial applications. Herein, we report the isolation of Halobacillus sp. HAL1, a moderately halophilic bacterium that produces a novel hi...

    Authors: Nayer M. Fahmy and Bahig El-Deeb
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:48
    Content type: Research Published on:

  22. Prostate cancer (PC) is a silent but potent killer among men. In 2018, PC accounted for more than 350, 000 death cases while more than 1.2 million cases were diagnosed. Docetaxel, a chemotherapeutic drug belon...

    Authors: Victor Omoboyede, Ochapa Ibrahim, Haruna Isiyaku Umar, Grace Ayomide Oke, Olugbenga Samson Onile and Prosper Obed Chukwuemeka
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:47
    Content type: Research Published on:

  23. Monkeypox virus is a small, double-stranded DNA virus that causes a zoonotic disease called Monkeypox. The disease has spread from Central and West Africa to Europe and North America and created havoc in some ...

    Authors: Kajal Gupta
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:46
    Content type: Research Published on:

    The Correction to this article has been published in Journal of Genetic Engineering and Biotechnology 2023 21:54

  24. Pectinase is helpful in food and beverage industries, particularly in the preparation of fruit juice, the extraction of vegetable oil, and the fermentation of coffee. The current work aimed to screen Aspergillus ...

    Authors: Mohd Taufiq Mat Jalil, Nurul Aili Zakaria, Nor Hawani Salikin and Darah Ibrahim
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:45
    Content type: Research Published on:

  25. Horseshoe crab (Tachypleus gigas) amebocytes are useful biomedical components for endotoxin detection, and their growing needs for biomedical purposes cause the horseshoe crab population to decline. Factor C synt...

    Authors: Apon Zaenal Mustopa, Ayu Fitri Izaki, Suharsono Suharsono, Fatimah Fatimah, Fauziyah Fauziyah, Rahmi Damarani, Arwansyah Arwansyah, Setyanto Tri Wahyudi, Siswi Sekar Sari, Rozirwan Rozirwan and Zubaidi Bachtiar
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:44
    Content type: Research Published on:

  26. MicroRNAs (miRNAs) are small endogenous RNAs with an approximate length of 18–22 nucleotides and involved in the regulation of gene expression in transcriptional or post-transcriptional levels. They were found...

    Authors: Foeaz Ahmed, Md. Nazmul Islam Bappy and Md. Shariful Islam
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:43
    Content type: Research Published on:

  27. Gymnema sylvestre (Retz.) R. Br. ex Schult. is a well-known medicinal plant against diabetes in India. There is as such no organized cultivation in India, and the plant is still being collected from the wild for ...

    Authors: Kanchana Vaishnav, Vandana Tiwari, Anjala Durgapal, Baleshwar Meena and T. S. Rana
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:42
    Content type: Research Published on:

  28. Lichens are complex plants living in symbiotic relationship between fungi and algae. They are used for human and animal nutrition and are used in folk medicine in many countries over a considerable period of t...

    Authors: Shubham Pradhan, Satyabrata Dash, Sabyasachy Parida, Bijayananda Sahoo and Biswajit Rath
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:41
    Content type: Research Published on:

  30. The dynamics of mammalian follicular development and atresia is an intricate process involving the cell-cell communication mediated by secreted ovarian factors. These interactions are critical for oocyte devel...

    Authors: Deepak Panwar, Leena Rawal and Sher Ali
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:39
    Content type: Research Published on:

  31. Hepatocellular carcinoma (HCC) is among the common cancers, but difficult to diagnose and treat. l-asparaginase has been introduced in the treatment protocol of pediatric acute lymphoblastic leukemia (ALL) since ...

    Authors: Dina H. El-Ghonemy, Sanaa A. Ali, Rehab M. Abdel-Megeed and Ali M. Elshafei
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:38
    Content type: Research Published on:

  32. Thermostable enzymes are enzymes that can withstand elevated temperatures as high as 50 Â°C without altering their structure or distinctive features. The potential of thermostable enzymes to increase the conver...

    Authors: Che Haznie Ayu Che Hussian and Wai Yie Leong
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:37
    Content type: Review Published on:

  33. The prevalence of diarrhoea remains high despite efforts by governments and NGOs to reverse trend. This study investigated the antidiarrhoeal activity and mechanism of Spondias mombin leaf fraction rich in querce...

    Authors: Olalekan Bukunmi Ogunro, Emmanuel Bankole Ofeniforo and Aderonke Elizabeth Fakayode
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:36
    Content type: Research Published on:

  34. The existence of mutated Delta (B.1.617.2) variants of SARS-CoV-2 causes rapid transmissibility, increase in virulence, and decrease in the effectiveness of public health. Majority of mutations are seen in the su...

    Authors: Sandhya KS and Achuthsankar S. Nair
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:35
    Content type: Research Published on:

  35. The cytochrome b (Cyt b) gene is one of the most studied mitochondrial DNA (mtDNA) genes to determine sheep’s genetic profile. This study aimed to determine the genetic diversity and relationships of several I...

    Authors: Alek Ibrahim, Endang Baliarti, I Gede Suparta Budisatria, Wayan Tunas Artama, Rini Widayanti, Dyah Maharani, Luis Tavares and Endang Tri Margawati
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:34
    Content type: Research Published on:

  36. Hepatitis E virus (HEV) is the cause of a liver disease hepatitis E. The translation product of HEV ORF2 has recently been demonstrated as a protein involved in multiple functions besides performing its major ...

    Authors: Zoya Shafat, Anwar Ahmed, Mohammad K. Parvez and Shama Parveen
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:33
    Content type: Research Published on:

  37. Seaweeds are a viable bioresource for suffering plants against salt stress, as they abundant in nutrients, hormones, vitamins, secondary metabolites, and many other phytochemicals that sustain plants' growth u...

    Authors: Marwa M. Hamouda, Abdelfattah Badr, Sameh S. Ali, Alia M. Adham, Hanan I. Sayed Ahmed and Khalil M. Saad-Allah
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:32
    Content type: Research Published on:

  38. Actinomycetes isolated from marine habitats are known to have the potential for novel enzymes that are beneficial in the industry. In-depth knowledge is necessary given the variety of this bacterial group in I...

    Authors: Hana Nadhifah, Nanik Rahmani, Wibowo Mangunwardoyo, Yopi, Akhirta Atikana, Shanti Ratnakomala and Puspita Lisdiyanti
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:31
    Content type: Research Published on:

  39. The Ag-NPs by green synthesis has a notable interest because of their eco-friendliness, economic views, feasibility, and applications in a wide range. Herein, native plants of Jharkhand (Polygonum plebeium, Litse...

    Authors: Koel Mukherjee, Namrata Bhagat, Madhubala Kumari, Arnab Roy Choudhury, Biplab Sarkar and Barnali Dasgupta Ghosh
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:30
    Content type: Research Published on:

  40. Phoebe goalparensis is an endemic forest species of North East India that belongs to Lauraceae family. P. goalparensis is used as timbers yielding plants for commercial importance in the local furniture markets o...

    Authors: Kalpataru Dutta Mudoi, Barbi Gogoi, Gitasree Borah, Marine Hussain, Tabassum Tasfia, Krishnakhi Borah, Himangshu Lekhak and Siddhartha Proteem Saikia
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:29
    Content type: Research Published on:

  41. Glutathione s-transferases (GSTs) perform an essential role in detoxification of xenobiotics and endogenous compounds via their conjugation to reduce glutathione.

    Authors: Hassan M. M. Masoud, Mohamed S. Helmy, Doaa A. Darwish and Mahmoud A. Ibrahim
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:28
    Content type: Research Published on:

  42. Saccharomyces cerevisiae (S. cerevisiae) has been demonstrated in vitro to sensitize several breast cancer cell lines and to be a safe, non-toxic drug with anti-skin cancer action in mice. Furthermore, plasmonic ...

    Authors: Amany Elwakkad, Amina A. Gamal el Din, Hisham A. Saleh, Noha E. Ibrahim, Mohamed A. Hebishy, Hagar H. Mourad, Mahitab I. El-Kassaby, Howida Sayed Abou-Seif and Ghada M. Elqattan
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:27
    Content type: Research Published on:

  43. Bletilla species are endangered terrestrial orchids used in natural skin care formulas in Asia for a long history. In order to explore the bioactivity potential of Bletilla species as a cosmetic ingredient in a s...

    Authors: Ruei-Ting Wang, Jui-Hung Yen, Yi-Chi Liao, Yi-Zhen Li and Wei-Ping Wang
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:26
    Content type: Research Published on:

  44. Enhancement of lipid accumulation is the major strategy to improve the commercial feasibility of microalgae as a source for biodiesel production. Pseudochlorella pringsheimii (Formally was named as Chlorella elli...

    Authors: Hanaa Abd El Baky and Gamal El Baroty
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:25
    Content type: Research Published on:

  45. Biopolymers like polyhydroxyalkanoates (PHA) are the best natural macromolecules to use as alternative to the synthetic polymers. Many prokaryotes accumulate PHA as cytoplasmic intracellular granules and their...

    Authors: Teja Mandragutti and G. Sudhakar
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:24
    Content type: Research Published on:

  46. The biopharmaceutical industry is significantly growing worldwide, and the Chinese hamster ovary (CHO) cells are used as a main expression host for the production of recombinant monoclonal antibodies. Various ...

    Authors: V. A. Toporova, V. V. Argentova, T. K. Aliev, A. A. Panina, D. A. Dolgikh and M. P. Kirpichnikov
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:23
    Content type: Research Published on:

  47. Invertebrates like crabs employ their own immune systems to fight against a number of invasive infections. Anti-lipopolysaccharide factors (ALFs) are an important class of antimicrobial peptides (AMPs) exhibit...

    Authors: M. V. Anju, K. Archana, V. V. Anooja, P. P. Athira, S. Neelima, I. S. Bright Singh and Rosamma Philip
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:22
    Content type: Research Published on:

  48. Superoxide dismutase is an important antioxidative stress enzyme which is found in honeybee venom and has a wide pharmaceutical and medical applications.

    Authors: Mohamed M. Abdel-Monsef, Doaa A. Darwish, Hind A. Zidan, Ahmed A. Hamed and Mahmoud A. Ibrahim
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:21
    Content type: Research Published on:

  49. Canine parvovirus (CPV) is a small virus without an envelope that consists of three viral proteins including VP1, VP2, and VP3. Exclusively, the VP2 can form a typically CPV-sized virus-like particle (CPV-VLP)...

    Authors: Mohammad Sadegh Hashemzadeh and Nariman Gharari
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:20
    Content type: Research Published on:

    The Correction to this article has been published in Journal of Genetic Engineering and Biotechnology 2023 21:40

  50. Bone morphogenetic protein receptor 1B (BMPR1B) gene is one of candidate genes for reproductive and growth traits in sheep. The present study was aimed to detect the Booroola (FecB) allele in BMPR1B gene and its ...

    Authors: Endang Tri Margawati, Widya Pintaka Bayu Putra, Muhammad Rizki, Edi Soetrisno and Herman Willem Raadsma
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:19
    Content type: Research Published on:
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  • ISSN: 2090-5920 (electronic)