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Journal of Genetic Engineering and Biotechnology
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  1. Tecothane (medical grade of polyurethane) is strongly involved in the fabrication of metallic and polymeric-based medical devices (e.g., catheters and stents) as they can withstand cardiac cycle-related forces...

    Authors: Reham G. Elfarargy, Mohamed Sedki, Farag A. Samhan, Rabeay Y. A. Hassan and Ibrahim M. El-Sherbiny
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:92
    Content type: Research Published on:

  2. Euphorbia resinifera is a melliferous, medicinal, and endemic plant to Morocco. Nevertheless, its ecological and genetic diversity still unknown. The objective of this study is to analyze the diversity and geneti...

    Authors: Hassane Abd-dada, Said Bouda, Youssef Khachtib, Youssef Ait Bella and Abdelmajid Haddioui
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:91
    Content type: Research Published on:

  3. Drug-resistant  Tuberculosis (DR-TB) is a global health burden with high morbidity and mortality in developing countries including Egypt. The susceptibility to infection with DR-TB strains may be genetically d...

    Authors: Asmaa A. Elmadbouly, Abeer Mohammed Abdul-Mohymen, Heba H. Eltrawy, Hanaa A. Abou Elhasan, Azza Ali Althoqapy and Doaa R. Amin
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:90
    Content type: Research Published on:

  4. Predictors of chronic HCV response to oral antiviral therapy (OAT) are related to host genetic variations. Single nucleotide polymorphisms (SNP) and alleles variations of host genes in association with hepatic...

    Authors: Al-Shazly Gaber Mohamed Galal, Reham M. Dawood, Mostafa K. El Awady, Yasser Mohamed Mohamed El-Dessouky, Mohamed Mahmoud Abdel-Halim Mahmoud and Mohamed Darwish Ahmed Abd Alla
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:89
    Content type: Research Published on:

  5. New-generation sequencing (NGS) techniques have brought the opportunity for genomic monitoring of several microorganisms potentially relevant to public health. The establishment of different methods with diffe...

    Authors: Leandro Menezes de Souza, Isabelle Dias de Oliveira, Flávia Cristina Silva Sales, Antonio Charlys da Costa, Karoline Rodrigues Campos, Adriano Abbud, Juliana Mariotti Guerra, Cinthya dos Santos Cirqueira Borges, Carlos Pires Fernandes Júnior Takahashi and Leonardo José Tadeu de Araújo
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:88
    Content type: Research Published on:

  6. Polycystic ovary syndrome is a common multifactorial endocrinopathy disorder affecting 5–15% of reproductive women worldwide. The CYP19 gene encodes key enzyme aromatase involved in androgen-to-estrogen conver...

    Authors: Pravesh Hegde, Shilpa S. Shetty, Prasanna Kumar Shetty, Lakshmi Manjeera, D. Prashanth Shetty and Suchetha Kumari
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:87
    Content type: Research Published on:

  7. It is important to comprehend how the molecular mechanisms shift when gastric cancer in its early stages (GC). We employed integrative bioinformatics approaches to locate various biological signalling pathways...

    Authors: Tamizh G. Selvan, Pavan Gollapalli, Santosh H. S. Kumar and Sudeep D. Ghate
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:86
    Content type: Research Published on:

  8. Up to date, a well-defined microRNAs (miRNAs) profile involved in hepatocellular carcinoma (HCC) pathogenesis remains indecisive. Thus, employing miRNAs for HCC diagnosis is demanded for early therapeutic inte...

    Authors: Sara M. Abdo, Wafaa Gh. Shousha, Amal Ahmed Mohamed, Mohamed Elshobaky, Mohamed Saleh and Mostafa Mohamed Abdelhamid Ali
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:85
    Content type: Research Published on:

  9. Soil metagenomics is a cultivation-independent molecular strategy for investigating and exploiting the diversity of soil microbial communities. Soil microbial diversity is essential because it is critical to s...

    Authors: Usha Chouhan, Umesh Gamad and Jyoti Kant Choudhari
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:84
    Content type: Research Published on:

  10. Myogenic enhancer transcription factor 2A (MEF2A) is a transcription factor known for its role in controlling skeletal muscle regeneration and metabolic processes, while activating transcription factor 3 (ATF3...

    Authors: Alfan Kurniawan, Muhammad Halim Natsir, Suyadi Suyadi, Osfar Sjofjan, Yuli Frita Nuningtyas, Ari Ardiantoro, Ahmad Furqon and Suci Puji Lestari
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:83
    Content type: Research Published on:

  11. Human nucleotide triphosphate diphosphatase (NUDT15) is one of the essential proteins involved in the hydrolysis of anti-cancer drugs against leukemia. Polymorphisms in NUDT15 significantly affect the hydrolys...

    Authors: Janakiraman V., Sudhan M., Khalaf F. Alsharif, Ibrahim F. Halawani, Shiek S. S. J. Ahmed and Shankargouda Patil
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:82
    Content type: Research Published on:

  12. About one-third of patients with estrogen receptor alpha (ERα)-positive breast cancer have tumors which are progesterone receptor (PR) negative. PR is an important prognostic factor in breast cancer. Patients ...

    Authors: Mariana Bustamante Eduardo, Irene Keller, Nathalie Schuster, Stefan Aebi and Rolf Jaggi
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:81
    Content type: Research Published on:

  13. The Pavo cristatus population, native to the Indian subcontinent, is thriving well in India. However, the Pavo muticus population, native to the tropical forests of Southeast Asia, has reduced drastically and has...

    Authors: Shahla Yasmin, Sushant Kumar and Gajendra Kumar Azad
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:80
    Content type: Research Published on:

  14. Colorectal Cancer (CRC) is the third most common cancer type and the second leading cause of cancer-related deaths worldwide. However, the existing treatment, as well as prognosis strategies for CRC patients, ...

    Authors: Mutebi John Kenneth, Tushar Ahmed Shishir and Fahim Kabir Monjurul Haque
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:79
    Content type: Research Published on:

  15. Tubulins are highly conserved globular proteins involved in stabilization of cellular cytoskeletal microtubules during cell cycle. Different isoforms of tubulins are differentially expressed in various cell ty...

    Authors: Polani B. Ramesh Babu
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:78
    Content type: Research Published on:

  16. Sheep is one of the commodities of livestock which has been known widely in Indonesia for supporting the national food security. Improvement in genetic quality by selection based on genetic markers for growth ...

    Authors: Puruhita, Ronny Rachman Noor, Endang Tri Margawati and Herman W. Raadsma
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:77
    Content type: Research Published on:

  17. Exopolysaccharides are extremely powerful molecules with a wide range of uses in pharmaceuticals due to their structural and compositional complexity. Marine microorganisms often produce bioactive substances w...

    Authors: Manal G. Mahmoud, Mohamed E. El Awady, Manal S. Selim, Abeer Y. Ibrahim, Faten M. Ibrahim and Sahar S. Mohamed
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:76
    Content type: Research Published on:

  18. Cancer is a major issue in medical science with increasing death cases every year worldwide. Therefore, searching for alternatives and nonorthodox methods of treatments with high efficiency, selectivity and le...

    Authors: Saja A. Ahmed, Ahmed F. Al-Shanon, Ali Z. Al-Saffar, Alene Tawang and Jameel R. Al-Obaidi
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:75
    Content type: Research Published on:

  19. The MYB family is one of the most significant groups of transcription factors in plants. However, several MYBs have been linked to secondary metabolism and are important for determining the color of fruit’s pe...

    Authors: Israr Ahmad, Sumit K. Soni, Muthukumar M. and Devendra Pandey
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:74
    Content type: Research Published on:

  20. Wild relatives of wheat are one of the most important genetic resources to use in wheat breeding programs. Therefore, identifying wild relatives of wheat and being aware of their diversity, is undeniably effec...

    Authors: Maryam Jabari, Ahmadreza Golparvar, Behzad Sorkhilalehloo and Majid Shams
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:73
    Content type: Research Published on:

  21. Due to the advantages of molecular methods over biochemical methods, the use of molecular methods for diagnosing nosocomial infections such as Pseudomonas can be an appropriate and rapid way to choose the right d...

    Authors: Zahra Mousivand, Fatemeh Haddadi and Hossein Kamaladini
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:72
    Content type: Research Published on:

  22. The forming, blending, and characterization of materials at a size of one billionth of a meter or less is referred to as nanotechnology. The objective of the current study was to synthesize ecologically friend...

    Authors: Krishnakumari N. Patel, Pooja G. Trivedi, Milan S. Thakar, Kush V. Prajapati, Dhruv K. Prajapati and Gaurang M. Sindhav
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:71
    Content type: Research Published on:

  23. Thottea siliquosa (Lamk.) Ding Hou., an important medicinal shrub, is widely used in both ayurvedic and indigenous systems of medicine. Root being the most useful part, the plant is constantly uprooted and thus p...

    Authors: Chandran Padikkal Krishna Vrundha and Thuruthiyil Dennis Thomas
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:70
    Content type: Research Published on:

  24. The root system is vital to plant growth and survival. Therefore, genetic improvement of the root system is beneficial for developing stress-tolerant and improved plant varieties. This requires the identificat...

    Authors: Samadhi S. Wimalagunasekara, Janith W. J. K. Weeraman, Shamala Tirimanne and Pasan C. Fernando
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:69
    Content type: Research Published on:

  25. Vaccination is the one of the agendas of many countries to reduce cervical cancer caused by the Human papillomavirus. Currently, VLP-based vaccine is the most potent vaccine against HPV, which could be produce...

    Authors: Moh Egy Rahman Firdaus, Apon Zaenal Mustopa, Nurlaili Ekawati, Sheila Chairunnisa, Rosyida Khusniatul Arifah, Ai Hertati, Shasmita Irawan, Anika Prastyowati, Arizah Kusumawati and Maritsa Nurfatwa
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:68
    Content type: Research Published on:

  26. Date palm, oasis pivot, plays a vital socio-economic part in the southern area of Morocco. However, with climate change and drought intensity and frequency increasing, the Moroccan palm grove is threatened wit...

    Authors: Maha Ibrahimi, Najiba Brhadda, Rabea Ziri, Mohamed Fokar, Driss Iraqi, Fatima Gaboun, Mustapha Labhilili, Aicha Habach, Reda Meziani, Jamal Elfadile, Rabha Abdelwahd and Ghizlane Diria
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:66
    Content type: Research Published on:

  27. Human insulin was the first FDA-approved biopharmaceutical drug produced through recombinant DNA technology. The previous studies successfully expressed recombinant human insulin precursors (HIP) in Pichia pastor...

    Authors: Nuruliawaty Utami, Dini Nurdiani, Hariyatun Hariyatun, Eko Wahyu Putro, Fadillah Putri Patria and Wien Kusharyoto
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:67
    Content type: Research Published on:

  28. SARS-CoV-2 infection involves disturbing multiple molecular pathways related to immunity and cellular functions. PIM1 is a serine/threonine-protein kinase found to be involved in the pathogenesis of several vi...

    Authors: Magda M. F. Ismail, Rehab R. El-Awady, Amal M. Farrag, Sara H. Mahmoud, Noura M. Abo Shama, Ahmed Mostafa, Mohamed A. Ali, Mohammed H. Rashed and Iman H. Ibrahim
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:65
    Content type: Research Published on:

  29. Arsenic, a ubiquitous toxic metalloid, is a threat to the survival of all living organisms. Bioaccumulation of arsenic interferes with the normal physiological pathway. To overcome arsenic toxicity, organisms ...

    Authors: Ashutosh Kabiraj, Anubhab Laha, Anindya Sundar Panja and Rajib Bandopadhyay
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:64
    Content type: Research Published on:

  30. Over the years, excessive use of chemical pesticides to control plant pathogens has caused environmental problems. Therefore, biological solutions such as the use of microorganisms with antimicrobial capacity ...

    Authors: Pelias Rafanomezantsoa, Samia Gharbi, Noureddine Karkachi and Mebrouk Kihal
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:63
    Content type: Research Published on:

  31. Adeno-associated virus (AAV) vectors have emerged as the leading delivery platforms for gene therapy. Throughout the life cycle of the virions, the capsid vector carries out diverse functions, ranging from cel...

    Authors: Yanqiao Shawn Xiang and Gang Gary Hao
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:62
    Content type: Review Published on:

  32. Calf rennet is considered the traditional source of milk clotting enzyme (MCE). However, increasing cheese consumption with decreasing the calf rennet supply had encouraged the quest for new rennet alternative...

    Authors: Hala R. Wehaidy, Mohamed A. Abdel-Naby, Adel M. M. Kholif, Mostafa Elaaser, Wafaa K. Bahgaat and Walaa A. Abdel Wahab
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:61
    Content type: Research Published on:

  34. Epigenome, genetic variants, and other environmental factors involved in gene regulation are highly inter-dependent in several chronic diseases, including obesity, cardiovascular disease, and diabetes. The pre...

    Authors: Sahar Abdulaziz AlSedairy, Laila Naif Al-Harbi, Manal Abdulaziz Binobead, Jegan Athinarayanan, Shaista Arzoo, Dalia Saade Al-Tamimi, Ghalia Shamlan, Ali Abdullah Alshatwi and Vaiyapuri Subbarayan Periasamy
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:59
    Content type: Research Published on:

  35. Sudangrass (Sorghum sudanense) is a major biomass producer for livestock feed and biofuel in many countries. It has a wide range of adaptations for growing on marginal lands under biotic and abiotic stresses. The...

    Authors: Shireen K. Assem, Mahmoud A. Basry, Taha A. Taha, M. H. Abd El-Aziz, Taher Alwa and Walid M. Fouad
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:58
    Content type: Research Published on:

  36. Streptococcus pneumoniae (SPN) is the agent responsible for causing respiratory diseases, including pneumonia, which causes severe health hazards and child deaths globally. Antibiotics are used to treat SPN as a ...

    Authors: Lincon Mazumder, Muhammad Shahab, Saidul Islam, Mahmuda Begum, Jonas Ivan Nobre Oliveira, Shamima Begum and Shahina Akter
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:57
    Content type: Research Published on:

  37. Garlic (Allium sativum L.) is the second most widely cultivated Allium which is mainly grown in temperate regions and used as a flavoring agent in a wide variety of foods. Garlic contains various bioactive compou...

    Authors: Malyaj R. Prajapati, Jitender Singh, Pankaj Kumar and Rekha Dixit
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:56
    Content type: Short Communications Published on:

  38. Nowadays, breakthroughs in molecular biology are happening at an unprecedented rate. One of them is the ability to engineer transgenic animals. A transgenic animal is one whose genome has been changed to carry...

    Authors: W. M. E. Shakweer, A. Y. Krivoruchko, Sh.M. Dessouki and A. A. Khattab
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:55
    Content type: Review Published on:

  40. MM (multiple myeloma) is a bone marrow disease with the accumulation of malignant plasma cells characterized by the neoplastic transformation of differentiated B cells.

    Authors: Akanksha A. Kalal, Reshma A. Shetty, Akshay Bairapura Manjappa, Nagaraj V. Kulkarni and Prashanth Shetty
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:50
    Content type: Research Published on:

  41. Finding natural products with anticancer activity is an effective strategy to fight this disease. In this respect, Lepidium sativum or garden cress (family Brassicaceae) has been widely used worldwide for its wid...

    Authors: Mona M. Ibrahim, Marwa M. Mounier and Shawky A. Bekheet
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:53
    Content type: Research Published on:

  42. Probiotics are live microorganisms that provide beneficial effects on the host’s health when exploited in adequate amounts. This study aimed at carrying out whole-genome sequence analysis and in vitro potentia...

    Authors: Nshimiyimana Sylvere, Apon Zaenal Mustopa, Sri Budiarti, Lita Meilina, Ai Hertati and Ira Handayani
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:49
    Content type: Research Published on:

  43. Zinc oxide nanoparticles (ZnO NPs) can be considered as nanofertilizer providing zinc as an essential micronutrient for plant growth and production at specific safe dose, however, above this dose; ZnO NPs indu...

    Authors: Doaa E. Elsherif, Eman Abd-ElShafy and Asmaa M. Khalifa
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:52
    Content type: Research Published on:

  44. Eighty-three strains of Leuconostoc mesenteroides were isolated from Algerian raw camel milk. Based on morphological, biochemical, and physiological characters tests, strains were identified as Ln. mesenteroides ...

    Authors: Hanane Fatma Chentouf, Fouzia Rahli, Zineb Benmechernene and Jorge Barros-Velazquez
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:51
    Content type: Research Published on:

  45. Hydrolytic enzymes from halophilic microorganisms have a wide range of industrial applications. Herein, we report the isolation of Halobacillus sp. HAL1, a moderately halophilic bacterium that produces a novel hi...

    Authors: Nayer M. Fahmy and Bahig El-Deeb
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:48
    Content type: Research Published on:

  46. Prostate cancer (PC) is a silent but potent killer among men. In 2018, PC accounted for more than 350, 000 death cases while more than 1.2 million cases were diagnosed. Docetaxel, a chemotherapeutic drug belon...

    Authors: Victor Omoboyede, Ochapa Ibrahim, Haruna Isiyaku Umar, Grace Ayomide Oke, Olugbenga Samson Onile and Prosper Obed Chukwuemeka
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:47
    Content type: Research Published on:

  47. Monkeypox virus is a small, double-stranded DNA virus that causes a zoonotic disease called Monkeypox. The disease has spread from Central and West Africa to Europe and North America and created havoc in some ...

    Authors: Kajal Gupta
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:46
    Content type: Research Published on:

    The Correction to this article has been published in Journal of Genetic Engineering and Biotechnology 2023 21:54

  48. Pectinase is helpful in food and beverage industries, particularly in the preparation of fruit juice, the extraction of vegetable oil, and the fermentation of coffee. The current work aimed to screen Aspergillus ...

    Authors: Mohd Taufiq Mat Jalil, Nurul Aili Zakaria, Nor Hawani Salikin and Darah Ibrahim
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:45
    Content type: Research Published on:

  49. Horseshoe crab (Tachypleus gigas) amebocytes are useful biomedical components for endotoxin detection, and their growing needs for biomedical purposes cause the horseshoe crab population to decline. Factor C synt...

    Authors: Apon Zaenal Mustopa, Ayu Fitri Izaki, Suharsono Suharsono, Fatimah Fatimah, Fauziyah Fauziyah, Rahmi Damarani, Arwansyah Arwansyah, Setyanto Tri Wahyudi, Siswi Sekar Sari, Rozirwan Rozirwan and Zubaidi Bachtiar
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:44
    Content type: Research Published on:

  50. MicroRNAs (miRNAs) are small endogenous RNAs with an approximate length of 18–22 nucleotides and involved in the regulation of gene expression in transcriptional or post-transcriptional levels. They were found...

    Authors: Foeaz Ahmed, Md. Nazmul Islam Bappy and Md. Shariful Islam
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:43
    Content type: Research Published on:
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  • ISSN: 2090-5920 (electronic)