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Journal of Genetic Engineering and Biotechnology
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  1. The M4 family of metalloproteases is comprised of a large number of zinc-containing metalloproteases. A large number of these enzymes are important virulence factors of pathogenic bacteria and therefore potent...

    Authors: Rajnee Hasan, Md. Nazmul Haq Rony and Rasel Ahmed
    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:25
    Content type: Research Published on:

  2. This study aimed to isolate potent thermophilic and amylolytic bacteria from a hot spring of Pharaoh’s bath, Sinai, Egypt, and screen its degradative activity. The amylolytic activity was further optimized usi...

    Authors: Ali M. Saeed, Einas H. El-Shatoury and Hayam A. E. Sayed
    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:24
    Content type: Research Published on:

  3. In this study, Vascular Endothelial Growth Factor 121 expressed abundantly in endometrial stromal cells is encapsulated with poly-l-lactide and characterized the properties for endometrial angiogenesis. We stu...

    Authors: Sunil Abraham, Geetha Sanjay, Noushin Abdul Majiyd and Amutha Chinnaiah
    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:23
    Content type: Research Published on:

  4. Melanocortin-1-receptor gene (MC1R) plays a significant role in signaling cascade of melanin production. In cattle, the coat colors, such as red and black, are an outcome of eumelanin and pheomelanin pigments, re...

    Authors: Talla Sridhar Goud, Ramesh Chandra Upadhyay, Vijaya Bhaskar Reddy Pichili, Suneel Kumar Onteru and Kiranmai Chadipiralla
    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:22
    Content type: Research Published on:

  5. Unlike chemical techniques, the combination of metal oxide nanoparticles utilizing plant concentrate is a promising choice. The purpose of this work was to synthesize magnesium oxide nanoparticles (MgO-NPs) ut...

    Authors: Manne Anupama Ammulu, K. Vinay Viswanath, Ajay Kumar Giduturi, Praveen Kumar Vemuri, Ushakiranmayi Mangamuri and Sudhakar Poda
    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:21
    Content type: Research Published on:

  6. Andrographis alata (Vahl) Nees is a medicinal plant which was reported to have the highest concentration of neoandrographolide that has several therapeutic values. Natural populations of Andrographis alata are dw...

    Authors: Sathish Shekhappa Kadapatti and Hosakatte Niranjana Murthy
    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:20
    Content type: Research Published on:

  7. Chitin is one of the most abundant biopolymers on Earth, only trailing second after cellulose. The enzyme chitinase is responsible for the degradation of chitin. Chitinases are found to be produced by wide ran...

    Authors: Bhramar Dutta, Jan Deska, Rajib Bandopadhyay and Salem Shamekh
    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:19
    Content type: Research Published on:

  9. Colorectal cancer (CRC) is one of the most frequently diagnosed tumors worldwide with high mortality and morbidity. There is an urgent need for biomarkers to improve the outcomes and early detection of CRC. Th...

    Authors: Manar S. Fouda, Rokaia M. Aljarwani, Khaled Aboul-Enein and Mohamed M. Omran
    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:17
    Content type: Research Published on:

  10. The World Health Organization has recently declared a new coronavirus disease (COVID-19) a pandemic and a global health emergency. The pressure to produce drugs and vaccines against the ongoing pandemic has re...

    Authors: Haruna Isiyaku Umar, Bushra Siraj, Adeola Ajayi, Tajudeen O. Jimoh and Prosper Obed Chukwuemeka
    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:16
    Content type: Research Published on:

  11. Detecting the genetic and physiological variations in two Japanese quail strains could be used to suggest a new avian model for future breeding studies. Consequently, two estimations were performed on two Japa...

    Authors: Nashat Saeid Ibrahim, Mohammed Ahmed El-Sayed, Heba Abdelwahab Mahmoud Assi, Ahmed Enab and Abdel-Moneim Eid Abdel-Moneim
    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:15
    Content type: Research Published on:

  12. Inflorescence explants of date palm proved to be a promising tool for micropropagation of elite cultivars or rare males and females as organogenesis and somatic embryogenesis could be achieved. These plant mat...

    Authors: Rania A. Taha, Mai A. Allam, S. A. M. Hassan, Basem M. M. Bakr and Mona M. Hassan
    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:14
    Content type: Research Published on:

  13. Bacteriocins are proteinaceous compounds produced from lactic acid bacteria. Bacteriocins are well-known for their antibacterial potential and safety for application in food. However, the commercial availabili...

    Authors: Sara Adel Amer, Hala Mohamed Abushady, Rasha Mohamed Refay and Mahmoud Ahmed Mailam
    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:13
    Content type: Research Published on:

  14. Tuberculosis (TB) remains a serious global health challenge that is caused by Mycobacterium tuberculosis and has killed numerous people. This necessitated the urgent need for the hunt and development of more pote...

    Authors: Mustapha Abdullahi, Shola Elijah Adeniji, David Ebuka Arthur and Abdurrashid Haruna
    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:12
    Content type: Research Published on:

  15. Asthenozoospermia is a chief reason for male seminal pathologies with an impression of around 19% of infertile patients. Spermatozoa mitochondrial DNA variations seem to link with low sperm motility. The objec...

    Authors: Mohamed M. Abd Elrahman, Aida I. El makawy, Mohamed S. Hassanane, Sally S. Alam, Nagwa H. A. Hassan and Medhat K. Amer
    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:11
    Content type: Research Published on:

  16. Honey bee venom contains various enzymes with wide medical and pharmaceutical applications.

    Authors: Doaa A. Darwish, Hassan M. M. Masoud, Mohamed M. Abdel-Monsef, Mohamed S. Helmy, Hind A. Zidan and Mahmoud A. Ibrahim
    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:10
    Content type: Research Published on:

  17. Nanomedicine has evolved as precision medicine in novel therapeutic approach of cancer management. The present study investigated the efficacy of biogenic gold nanoparticles synthesized using Argemone mexicana L....

    Authors: Kailas D. Datkhile, Satish R. Patil, Pratik P. Durgawale, Madhavi N. Patil, Dilip D. Hinge, Nilam J. Jagdale, Vinit N. Deshmukh and Ashwini L. More
    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:9
    Content type: Research Published on:

  18. The crucial factor in the production of bio-fuels is the choice of potent microorganisms used in fermentation processes. Despite the evolving trend of using bacteria, yeast is still the primary choice for ferm...

    Authors: Jemal Aman Beshir and Mulugeta Kebede
    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:8
    Content type: Research Published on:

  19. Cellulases are well known for their various industrial applications. They are naturally produced by different species of bacteria and fungi. Fermentation process of cellulase producers has limitation due to th...

    Authors: Bhuvan Shankar Vadala, Sumedh Deshpande and Anjali Apte-Deshpande
    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:7
    Content type: Research Published on:

  20. Breast cancer is a disease in which cell grows rapidly forming a mass in the breast. HER2 polymorphisms Ile655Val have been studied as biomarkers for breast cancer and may comprise a risk factor of cardiac tox...

    Authors: Desriani, Azamris, Shabrina S. Ghaissani, Senja R. Kinanti, Muhammad A. Warisman and N. Fitria
    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:6
    Content type: Research Published on:

  21. Crop wild relatives (CWRs) are commonly used as a suitable genetic reservoir for plant breeding. They can be used for enhancing the tolerance of plant varieties to biotic and abiotic stresses. Studying the gen...

    Authors: Lavin Khodaee, Reza Azizinezhad, Ali Reza Etminan and Mahmoud Khosroshahi
    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:5
    Content type: Research Published on:

  22. Induced polyploidy serves as an efficient approach in extricating genetic potential of cells. During polyploidization, multiple sets of chromosomes are derived from the same organism resulting in the developme...

    Authors: Saikat Gantait and Eashan Mukherjee
    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:4
    Content type: Review Published on:

  23. Heparanase activity was found to be included in human cancer development and growth. Heparanase (HPSE) gene single nucleotide polymorphisms (SNPs) have been found to be correlated with different human cancers. In...

    Authors: Faten Saad, Mahmoud Gadallah, Ahmed Daif, Nahed Bedair and Moustafa A. Sakr
    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:3
    Content type: Research Published on:

  24. Barley (Hordeum vulgare L.) is one of the most important cereals worldwide. Although this crop is drought-tolerant, water deficiency negatively affects its growth and production. To detect key genes involved in d...

    Authors: Seyedeh Mehri Javadi, Zahra-Sadat Shobbar, Asa Ebrahimi and Maryam Shahbazi
    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:2
    Content type: Research Published on:

    The Correction to this article has been published in Journal of Genetic Engineering and Biotechnology 2021 19:78

  25. Rhizopus species is among the most well-known lipase producers, and its enzyme is suitable for use in many industrial applications. Our research focuses on the production of lipase utilizing waste besides eval...

    Authors: Shimaa E. Helal, Hemmat M. Abdelhady, Khadiga A. Abou-Taleb, Mervat G. Hassan and Mahmoud M. Amer
    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:1
    Content type: Research Published on:

  26. Biologically important curcuminoids viz curcumin, demethoxycurcumin, and bisdemethoxycurcumin in turmeric rhizome have several health benefits. Pharmaceutical industries synthesize curcuminoids manipulating ge...

    Authors: Dipendra Kumar Ayer, Kaushal Modha, Vipulkumar Parekh, Ritesh Patel, Gopal Vadodariya, Vinita Ramtekey and Arpit Bhuriya
    Citation: Journal of Genetic Engineering and Biotechnology 2020 18:83
    Content type: Research Published on:

  27. Bryophytes, comprising of the second largest group in the plant kingdom, has attracted a great deal of attention in recent years due to its immense potential to produce biopharmaceuticals. But studies conducte...

    Authors: Rashmi Mishra and Ramesh Chandra
    Citation: Journal of Genetic Engineering and Biotechnology 2020 18:82
    Content type: Research Published on:

  28. Xylanase has long been recognized as a widely used industrially important enzyme. There are some bacterial species already reported to produce xylanase which have potent xylanolytic activity towards the use of...

    Authors: Manish Paul, Dipti Pravamayee Nayak and Hrudayanath Thatoi
    Citation: Journal of Genetic Engineering and Biotechnology 2020 18:81
    Content type: Research Published on:

  29. Plasmid propagation in recombination strains such as Escherichia coli DH5α is regarded as a beneficial instrument for stable amplification of the DNA materials. Here, we show trans-conjugation of pGEM-T cloning v...

    Authors: Ahmed A. Hamed, Mohamed Khedr and Mohamed Abdelraof
    Citation: Journal of Genetic Engineering and Biotechnology 2020 18:80
    Content type: Research Published on:

  30. Due to the multitude industrial applications of ligninolytic enzymes, their demands are increasing. Partial purification and intensive characterization of contemporary highly acidic laccase enzyme produced by ...

    Authors: Soad A. Abdelgalil, Ahmad R. Attia, Reyed M. Reyed and Nadia A. Soliman
    Citation: Journal of Genetic Engineering and Biotechnology 2020 18:79
    Content type: Research Published on:

  31. At present, viral diseases become major concern for the world. SARS-CoV2 and SFTS viruses are deadly in nature, and there is a need for developing best treatments for them. Modern in silico approaches were fou...

    Authors: Amit Joshi, G. Sunil Krishnan and Vikas Kaushik
    Citation: Journal of Genetic Engineering and Biotechnology 2020 18:78
    Content type: Research Published on:

  32. Phytochromes are plant photoreceptors that have long been associated with photomorphogenesis in plants; however, more recently, their crucial role in the regulation of variety of abiotic stresses has been expl...

    Authors: Raheel Shahzad, Faraz Ahmed, Zheng Wang, Putri Widyanti Harlina, Elsayed Nishawy, Mohamed Ayaad, Abdul Manan, Mohamed Maher and Mohamed Ewas
    Citation: Journal of Genetic Engineering and Biotechnology 2020 18:77
    Content type: Research Published on:

  33. To achieve a high yield of terpenoid-based therapeutics, 1-deoxy-d-xylulose-5-phosphate (DXP) pathway has been significantly exploited for the production of downstream enzymes. The DXP synthase (DXS) enzyme, t...

    Authors: Ashish Runthala, Tavakala Harsha Sai, Vandana Kamjula, Suresh C. Phulara, Vikrant Singh Rajput and Karthikeyan Sangapillai
    Citation: Journal of Genetic Engineering and Biotechnology 2020 18:76
    Content type: Short Communications Published on:

  34. Nucleotide-binding site-leucine-rich repeat (NBS-LRR) resistance genes are the largest class of plant resistance genes which play an important role in the plant defense response. These genes are better conserv...

    Authors: R. Chandrakanth, L. Sunil, L. Sadashivaiah and N. S. Devaki
    Citation: Journal of Genetic Engineering and Biotechnology 2020 18:75
    Content type: Research Published on:

  35. The multidrug resistance (MDR) of cancer cells is a major obstacle to cancer treatment. Glutathione S-transferase Pi (GSTP1-1) catalyzes the conjugation of glutathione with anticancer drugs and therefore reduc...

    Authors: R. A. Guneidy, A. M. Gad, E. R. Zaki, F. M. Ibrahim and A. Shokeer
    Citation: Journal of Genetic Engineering and Biotechnology 2020 18:74
    Content type: Research Published on:

  37. The techniques of amplifying genetic materials have enabled the extensive study of several biological activities outside the biological milieu of living systems. More recently, this approach has been extended ...

    Authors: Prosper Obed Chukwuemeka, Haruna Isiyaku Umar, Oluwatoyin Folake Olukunle, Oluwaseyi Matthew Oretade, Christopher Busayo Olowosoke, Emmanuel Oluwasegun Akinsola, Michael Omoniyi Elabiyi, Usman Garba Kurmi, Joy Oseme Eigbe, Bukola Rukayat Oyelere, Lucky Efe Isunu and Oyeyemi Janet Oretade
    Citation: Journal of Genetic Engineering and Biotechnology 2020 18:72
    Content type: Research Published on:

  38. Plant growth-promoting rhizobacteria (PGPR) are known to improve plant growth and are used as biofertilizers, thanks to their numerous benefits to agriculture such as phosphorus solubilization and phytohormone...

    Authors: Sara Lebrazi, Karsten Niehaus, Hanna Bednarz, Mouhcine Fadil, Marwa Chraibi and Kawtar Fikri-Benbrahim
    Citation: Journal of Genetic Engineering and Biotechnology 2020 18:71
    Content type: Research Published on:

  39. Soils polluted with animal charcoal from skin and hide cottage industries harbour extremely toxic and carcinogenic hydrocarbon pollutants and thus require a bio-based eco-friendly strategy for their depuration...

    Authors: Lateef Babatunde Salam and Oluwafemi Sunday Obayori
    Citation: Journal of Genetic Engineering and Biotechnology 2020 18:70
    Content type: Research Published on:

  40. The COVID-19 pandemic caused by SARS-CoV-2 has shown an exponential trend of infected people across the planet. Crediting its virulent nature, it becomes imperative to identify potential therapeutic agents aga...

    Authors: Ekampreet Singh, Rameez Jabeer Khan, Rajat Kumar Jha, Gizachew Muluneh Amera, Monika Jain, Rashmi Prabha Singh, Jayaraman Muthukumaran and Amit Kumar Singh
    Citation: Journal of Genetic Engineering and Biotechnology 2020 18:69
    Content type: Review Published on:

  41. Development of efficient strategies has always been one of the great perspectives for biotechnologists. During the last decade, genome editing of different organisms has been a fast advancing field and therefo...

    Authors: Ahmad M. Khalil
    Citation: Journal of Genetic Engineering and Biotechnology 2020 18:68
    Content type: Review Published on:

  42. Translating the conventional scientific concepts into a new robust invention is a much needed one at a present scenario to develop some novel materials with intriguing properties. Particles in nanoscale exhibi...

    Authors: Sunita Patil and Rajkuberan Chandrasekaran
    Citation: Journal of Genetic Engineering and Biotechnology 2020 18:67
    Content type: Review Published on:

  43. Endophyte bestows beneficial aspects to its inhabiting host, along with a contribution to diverse structural attributes with biological potential. In this regard, antimicrobial profiling of fungal endophytes f...

    Authors: Kolathuru Puttamadaiah Ramesha, Nagabhushana Chandra Mohana, Bettadapura Rameshgowda Nuthan, Devaraju Rakshith and Sreedharamurthy Satish
    Citation: Journal of Genetic Engineering and Biotechnology 2020 18:66
    Content type: Research Published on:

  44. Xylanase is one of the widely applied industrial enzymes with diverse applications. Thermostability and alkali tolerance are the two most desirable qualities for industrial applications of xylanase. In this pa...

    Authors: Girisha Malhotra and Shilpa S. Chapadgaonkar
    Citation: Journal of Genetic Engineering and Biotechnology 2020 18:65
    Content type: Research Published on:

  45. Various polymerase chain reaction (PCR)-based methods have been applied for the development of genome walking (GW) technique. These methods which could be based on the application of restriction enzymes or pri...

    Authors: Seyedeh-Samira Ashrafmansouri, Hossein Kamaladini, Fatemeh Haddadi and Marie Seidi
    Citation: Journal of Genetic Engineering and Biotechnology 2020 18:64
    Content type: Research Published on:

  46. Fluorescence In Situ Hybridization (FISH) played an essential role to locate the ribosomal RNA genes on the chromosomes that offered a new tool to study the chromosome structure and evolution in plant. The 45S an...

    Authors: Hoda B. M. Ali and Samira A. Osman
    Citation: Journal of Genetic Engineering and Biotechnology 2020 18:63
    Content type: Research Published on:

  47. Ethylene is a gaseous plant hormone that acts as a requisite role in many aspects of the plant life cycle, and it is also a regulator of plant responses to abiotic and biotic stresses. In this study, we attemp...

    Authors: Mostafa Ahmadizadeh, Jen-Tsung Chen, Soosan Hasanzadeh, Sunny Ahmar and Parviz Heidari
    Citation: Journal of Genetic Engineering and Biotechnology 2020 18:62
    Content type: Research Published on:

  48. Biodiesel has gained an increased popularity as a good alternative for fossil fuel because of its unusual qualities as a biodegradable, nontoxic, and renewable diesel fuel. Hence, the economic utilization of t...

    Authors: Wesam Taha Basal, Aliaa Mahmoud Issa, Shehab Eldin Sayed Mohammed and Saher Abd-Elhafeez Mazen
    Citation: Journal of Genetic Engineering and Biotechnology 2020 18:61
    Content type: Research Published on:

  49. Nitroreductases are a family of evolutionarily related proteins catalyzing the reduction of nitro-substituted compounds. Nitroreductases are widespread enzymes, but nearly all modern research and practical app...

    Authors: Siarhei A. Dabravolski
    Citation: Journal of Genetic Engineering and Biotechnology 2020 18:60
    Content type: Research Published on:

  50. Halophiles offer an attractive source of genes conferring salt tolerance. Halobacillus trueperi SS1 strain of Lunsu, Himachal Pradesh, India, a strict halophile, was exploited to isolate and clone the genes for s...

    Authors: Sonika Gupta, Parul Sharma, Kamal Dev and Anuradha Sourirajan
    Citation: Journal of Genetic Engineering and Biotechnology 2020 18:57
    Content type: Research Published on:
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  • ISSN: 2090-5920 (electronic)