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Journal of Genetic Engineering and Biotechnology
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  1. In seek of potent and non-toxic iminoguanidine derivatives formerly assessed as active Pseudomonas aeruginosa inhibitors, a combined mathematical approach of quantitative structure-activity relationship (QSAR)...

    Authors: Emmanuel Israel Edache, Adamu Uzairu, Paul Andrew Mamza and Gideon Adamu Shallangwa
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:88
    Content type: Research Published on:

  2. Lignocellulosic biomasses produced from agriculture and forest-based industries are the cheapest or negative-cost biomass with a great potential for biotransformation to value-added bioproducts. Paper mill slu...

    Authors: Tuhin Das, Ferdausi Ali and Md. Shafiqur Rahman
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:87
    Content type: Research Published on:

  3. Aegilops tauschii Coss. as a donor of wheat D genome has an important role in wheat breeding programs. Genetic and phylogeographic diversity of 79 Ae. tauschii accessions collected from north and northwest of Ira...

    Authors: Sona Minaei, Seyyed Abolghasem Mohammadi, Atefeh Sabouri and Ahmad Reza Dadras
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:86
    Content type: Research Published on:

  4. This study was designed to generate functional insulin-producing cells (IPCs) from dental-derived mesenchymal stem cells (MSCs) and further explore their therapeutic potential against diabetes mellitus in vivo...

    Authors: Riham M. Aly, Hadeer A. Aglan, Ghada Nour Eldeen, Nadia S. Mahmoud, Eman H. Aboul-Ezz and Hanaa H. Ahmed
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:85
    Content type: Research Published on:

  5. Fibroblast growth factor 21 (FGF-21), alpha-amylase, and alpha-glucosidase are key proteins implicated in metabolic dysregulations. Bisphenol A (BPA) is an environmental toxicant known to cause endocrine dysre...

    Authors: P. M. Aja, J. N. Awoke, P. C. Agu, A. E. Adegboyega, E. M. Ezeh, I. O. Igwenyi, O. U. Orji, O. G. Ani, B. A. Ale and U. A. Ibiam
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:84
    Content type: Research Published on:

  6. Schizophrenia is a chronic mental disorder with different symptoms. The environmental and genetic factors are suggested to be the etiology of schizophrenia. However, the exact cause and pathogenesis of schizop...

    Authors: Maged Mostafa, Aya Ahmed Fathy, Mohamed Elwasify and Maha Abdelsalam
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:83
    Content type: Research Published on:

  7. Protease is one of the most important industrial enzymes. The importance of protease bioproduction comes from meeting the increasing demand for this enzyme especially in the cheese industry. Rhizomucor miehei pro...

    Authors: Houthail Alahmad Aljammas, Sabah Yazji and Abdulhakim Azizieh
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:82
    Content type: Research Published on:

  8. Antarctica is one of the harshest environments in the world. Despite this fact, it has been colonized by microorganisms, which had to develop different adaptations in order to survive. By studying their enzyme...

    Authors: P. Rios, B. Bezus, S. Cavalitto and I. Cavello
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:81
    Content type: Research Published on:

  9. Sugarcane hemicellulosic material is a compelling source of usually neglected xylose that could figure as feedstock to produce chemical building blocks of high economic value, such as xylitol. In this context, Sa...

    Authors: Fellipe da Silveira Bezerra de Mello, Carla Maneira, Frank Uriel Lizarazo Suarez, Sheila Nagamatsu, Beatriz Vargas, Carla Vieira, Thais Secches, Alessando L. V. Coradini, Maria Augusta de Carvalho Silvello, Rosana Goldbeck, Gonçalo Amarante Guimarães Pereira and Gleidson Silva Teixeira
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:80
    Content type: Research Published on:

  10. Successful rhizosphere colonization by plant growth promoting rhizobacteria (PGPR) is of crucial importance to perform the desired plant growth promoting activities. Since rhizocompetence is a dynamic process ...

    Authors: Donia S. Helal, Hussein El-khawas and Tarek R. Elsayed
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:79
    Content type: Research Published on:

  11. COVID-19 is an illness caused by severe acute respiratory syndrome coronavirus 2. Due to its rapid spread, in March 2020 the World Health Organization (WHO) declared pandemic. Since the outbreak of pandemic ma...

    Authors: Abas Sezer, Mervisa Halilović-Alihodžić, Annissa Rachel Vanwieren, Adna Smajkan, Amina Karić, Husein Djedović and Jasmin Šutković
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:78
    Content type: Review Published on:

  12. Newcastle disease virus (NDV) belongs to the genus Avaluvirus and Paramyxoviridae family, and it can cause acute, highly contagious Newcastle disease in poultry. The two proteins, haemagglutinin neuraminidase (HN...

    Authors: Mohammadreza Shafaati, Masoud Ghorbani, Minoo Mahmoodi, Mostafa Ebadi and Reza Jalalirad
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:77
    Content type: Research Published on:

  13. Many active peptides have been found in frog skin secretions. In this paper, our research focused on Pelophylax nigromaculatus and found a broad-spectrum antimicrobial peptide Nigrocin-PN based on the molecular c...

    Authors: Chengyu Lu, Lingling Liu, Chengbang Ma, Liuqing Di and Tianbao Chen
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:76
    Content type: Research Published on:

  14. Metabolic syndrome (MetS) is a combination of many health complications, such as obesity, high blood pressure, hyperlipidemia, hyperglycemia, and insulin resistance, with an increasing threat of type 2 diabete...

    Authors: Amira Mohamed Abd El-Jawad, Iman Hassan Ibrahim, Moushira Erfan Zaki, Tahany Ramzy Elias, Wafaa Ibrahim Rasheed and Khalda Said Amr
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:75
    Content type: Research Published on:

  15. Gongronella butleri is a fungus with many industrial applications including the composting of solid biowaste. Kerala Agricultural University, India, has developed a microbial consortium of which GbKAU strain of G...

    Authors: Ravisankar Valsalan, Deepu Mathew and Girija Devaki
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:74
    Content type: Research Published on:

  17. Among the most common causes of invasive aspergillosis and acute bronchopulmonary aspergillosis is Aspergillus fumigatus. Transmission with A. fumigatus produces aggressive aspergillosis in allogeneic haematopoie...

    Authors: Darakshan Jabin and Ajay Kumar
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:72
    Content type: Research Published on:

  18. In the past, simple sequence repeat (SSR) marker development in coconut is achieved through microsatellite probing in bacterial artificial chromosome (BAC) clones or using previously developed SSR markers from...

    Authors: Reina Esther S. Caro, Jesmar Cagayan, Roanne R. Gardoce, Anand Noel C. Manohar, Alma O. Canama-Salinas, Ramon L. Rivera, Darlon V. Lantican, Hayde F. Galvez and Consorcia E. Reaño
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:71
    Content type: Research Published on:

  19. Several SARS-CoV-2 variants with increased transmissibility and/or potential immune escape have emerged and rapidly spread worldwide. Ongoing surveillance analyses are performed worldwide to designate new vari...

    Authors: Ghada Ismail, Hossam Abdelghaffar, Mohamed G. Seadawy, Mostafa F. El-Hosseny, Ahmed F. Gad, Amr Ageez, Ahmed ElShafei, Shereen Saeed Mohammed, Marym Saied Ali and Marwa abd El-Rasoul El-Ashry
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:70
    Content type: Short Communications Published on:

  21. Nonalcoholic fatty liver disease (NAFLD) showed significant association with PNPLA3 rs738409 polymorphism in unrelated individuals. However, it is still unknown whether the relationship of NAFLD with PNPLA3 varia...

    Authors: Muhammad Adnan, Abdul Wajid, Wasif Noor, Andleeb Batool, Muhammad Aasim, Kamran Abbas and Quratul Ain
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:68
    Content type: Research Published on:

  22. The green peach aphid, Myzus persicae Sulzer, and the bean aphid, Aphis fabae Scopoli (both Hemiptera: Aphididae), are serious pests of greenhouse vegetable crops in Iraq and other regions of the globe. In this s...

    Authors: Akram A. Mohammed, Firas A. Ahmed, Amal S. Younus, Ali A. Kareem and Ali M. Salman
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:67
    Content type: Research Published on:

  23. Tamoxifen resistance in estrogen receptor positive (ER+) breast cancer therapy increases, which is the leading cause of cancer treatment failure, as it can impair patients’ prognoses, cause cancer recurrence, ...

    Authors: Wilfan Ibadurrahman, Naufa Hanif and Adam Hermawan
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:66
    Content type: Research Published on:

  24. The global COVID-19 pandemic caused by SARS-CoV2 infected millions of people and resulted in more than 4 million deaths worldwide. Apart from vaccines and drugs, RNA silencing is a novel approach for treating ...

    Authors: Vijaya Sai Ayyagari
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:65
    Content type: Short Communications Published on:

  25. Cancer is a group of diseases involving abnormal cell growth with the potential to invade or spread to other parts of the body. It is unlikely that there will ever be a single cure for cancer, but the developm...

    Authors: Lingling Liu, Xunan Wang, Yue Li, Chengyao Ma, Yeye Shi, Xiang Li and Jianwei Chen
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:64
    Content type: Research Published on:

  26. DNA barcoding is a powerful method for phylogenetic mapping and species identification. However, recent research has come to a consistent conclusion about the universality of DNA barcoding. We used matK and rbcL ...

    Authors: Ravi Prakash Srivastava, Gauri Saxena, Lav Singh, Arpit Singh, Praveen C. Verma and Gurminder Kaur
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:63
    Content type: Research Published on:

  27. During the last decade, enormous research efforts have been directed at identifying potent microorganisms as sustainable green cell factories for eco-friendly pigments. Talaromyces atroroseus has recently been sh...

    Authors: Rasha G. Salim, Mohamed Fadel, Yehya A. Youssef, Hanan A. A. Taie, Nivien A. Abosereh, Ghada M. El-Sayed and Mohamed Marzouk
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:62
    Content type: Research Published on:

  28. Salicornia is a halophyte plant capable of being irrigated with seawater, which can be used as an alternative food. Given this, it is necessary to study the potentials of this plant’s morphological diversity in ...

    Authors: Mohammad Aghaei, Abbas Hassani, Hosein Nazemiyeh, Babak Abdollahi Mandoulkani and Mohammad Saadatian
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:61
    Content type: Research Published on:

  29. The novel coronavirus (SARS-CoV-2) caused lethal infections worldwide during an unprecedented pandemic. Identification of the candidate viral epitopes is the first step in the design of vaccines against the vi...

    Authors: Nourelislam Awad, Rania Hassan Mohamed, Nehal I. Ghoneim, Ahmed O. Elmehrath and Nagwa El-Badri
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:60
    Content type: Research Published on:

    The Correction to this article has been published in Journal of Genetic Engineering and Biotechnology 2022 20:69

  30. Periodontitis is a multi-factorial infection with red complex bacteria playing a crucial role in the pathogenesis. As bacteria are tending to develop resistance against conventional antibiotics, new treatment ...

    Authors: Harini Venkata Subbiah, Polani Ramesh Babu and Usha Subbiah
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:59
    Content type: Research Published on:

  31. The recent severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection cause high mortality and there is an emergency need to develop a specific drug to treat the novel coronavirus disease, COVID-19...

    Authors: Ravichandran Veerasamy and Rohini Karunakaran
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:58
    Content type: Research Published on:

  32. The enormous and irresponsible use of antibiotics has led to the emergence of resistant strains of bacteria globally. A new approach to combat this crisis has been nutritional immunity limiting the availabilit...

    Authors: Anil H. Shyam Mohan, Saroja Narsing Rao, Srividya D. and N. Rajeswari
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:57
    Content type: Research Published on:

  33. Hepatitis E virus (HEV) is a positive-sense RNA virus belonging to the family Hepeviridae. The genome of HEV is organized into three open-reading frames (ORFs): ORF1, ORF2, and ORF3. The ORF1 non-structural Y-d...

    Authors: Zoya Shafat, Anwar Ahmed, Mohammad K. Parvez and Shama Parveen
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:56
    Content type: Research Published on:

  34. Mycobacterium tuberculosis has been ravaging humans by inflicting respiratory tuberculosis since centuries. Bacillus Calmette Guerine (BCG) is the only vaccine available for tuberculosis, and it is known to be p...

    Authors: Kaviya Parambath Kootery and Suma Sarojini
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:55
    Content type: Research Published on:

  35. Salmonella enterica serovar Typhimurium (S. Typhimurium) causes gastroenteritis and diarrhea in humans and food-producing animals. The type III secretion system (T3SS) has been known to be a potent virulence mec...

    Authors: Rerngwit Boonyom, Sittiruk Roytrakul and Patipat Thinwang
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:54
    Content type: Research Published on:

  36. Mycobacterium colombiense is an acid-fast, non-motile, rod-shaped mycobacterium confirmed to cause respiratory disease and disseminated infection in immune-compromised patients, and lymphadenopathy in immune-comp...

    Authors: Feyissa Hamde, Hunduma Dinka and Mohammed Naimuddin
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:53
    Content type: Research Published on:

  37. Sphingomonas wittichii RW1 is one out of three strains capable of metabolizing dioxin as a sole source for carbon and energy. Under laboratory conditions the degradation rates for these aromatics are relatively h...

    Authors: Rayan M. Faisal and Aveen H. Rasol
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:52
    Content type: Research Published on:

  38. The nitrile compounds are produced either naturally or synthetically and are highly used in many manufacturing industries such as pharmaceuticals, pesticides, chemicals, and polymers. However, the extensive us...

    Authors: M. Amrutha and K. Madhavan Nampoothiri
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:51
    Content type: Research Published on:

  39. Thermo-alkali stable xylanases were purified from the extracellular broth of newly isolated Bacillus licheniformis strain produced in a 5-L stirred-tank bioreactor with wheat bran as a carbon source.

    Authors: Girisha Malhotra and Shilpa S. Chapadgaonkar
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:50
    Content type: Research Published on:

  40. Increase of antibiotic resistance in pathogenic microbes necessitated novel molecules for curing infection. Antimicrobial peptides (AMPs) are the gene-encoded evolutionarily conserved small molecules with ther...

    Authors: P. P. Athira, V. V. Anooja, M. V. Anju, S Neelima, K. Archana, S. Muhammed Musthafa, Swapna P. Antony, I. S. Bright Singh and Rosamma Philip
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:49
    Content type: Research Published on:

  42. Leukemia inhibitory factor (LIF) is a multifunctional cytokine which plays multiple roles in different biological processes such as implantation, bone remodeling, and hematopoiesis. The buESCs are difficult to...

    Authors: Shradha Jamwal, Shama Ansari, Dhruba Malakar, Jai Kumar Kaushik, Sudarshan Kumar and Ashok Kumar Mohanty
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:47
    Content type: Research Published on:

  43. The Philippines is among the top 10 major exporters of mango worldwide. However, genomic studies of Philippine mangoes remain largely unexplored and lacking. Here, we sequenced the whole genome of the three Ph...

    Authors: Cris Q. Cortaga, John Albert P. Lachica, Darlon V. Lantican and Eureka Teresa M. Ocampo
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:46
    Content type: Research Published on:

  44. Tomatoes (Solanum lycopersicon L.) are one of the main daily consumed vegetables in the human diet. Tomato has been classified as moderately sensitive to salinity at most stages of plant development, including se...

    Authors: Ibrahim M. Makhadmeh, Samar G. Thabet, Mohammed Ali, Basmah Alabbadi, Ammar Albalasmeh and Ahmad M. Alqudah
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:45
    Content type: Research Published on:

  45. Methyl CpG binding protein 2 (MeCP2) is essential for the normal function of mature neurons. Mutations in the MECP2 gene are the main cause of Rett syndrome (RTT). Gene mutations have been identified throughou...

    Authors: Wessam E. Sharaf-Eldin, Mahmoud Y. Issa, Maha S. Zaki, Ayman Kilany and Alaaeldin G. Fayez
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:44
    Content type: Research Published on:

  46. The derivatives of quercetin is known for their immune-modulating antiviral, anti-blood clotting, antioxidant, and also for its anti-inflammatory efficacy. The current study was therefore conducted to examine ...

    Authors: Kunal Bhattacharya, Ripunjoy Bordoloi, Nongmaithem Randhoni Chanu, Ramen Kalita, Bhargab Jyoti Sahariah and Atanu Bhattacharjee
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:43
    Content type: Research Published on:

  47. Efforts toward the development of an effective vaccine against Acinetobacter baumannii, one of the most notorious nosocomial pathogens, are still ongoing. In this regard, virulence factors are interesting targets...

    Authors: Saeed Alipouri, Iraj Rasooli, Mohammad Hossein Ghaini, Abolfazl Jahangiri, Shakiba Darvish Alipour Astaneh and Fatemeh Ramezanalizadeh
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:42
    Content type: Research Published on:

  48. The Tropheryma whipplei causes acute gastroenteritis to neuronal damages in Homo sapiens. Genomics and codon adaptation studies would be helpful advancements of disease evolution prediction, prevention, and treat...

    Authors: Amit Joshi, Sunil Krishnan and Vikas Kaushik
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:41
    Content type: Research Published on:

  49. Piper hispidinervum is a species native from the Amazon region with great economic potential, given its scientifically proven insecticidal properties. In this study, an efficient protocol of plant regeneration v...

    Authors: Paulo Cesar Alves de Sousa, Stênio Steferson Silva e Souza, Gabriela Ferreira Nogueira, Inaê Mariê de Araújo Silva-Cardoso and Jonny Everson Scherwinski-Pereira
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:40
    Content type: Research Published on:

  50. Durian of Indonesia, specifically Durio zibethinus, is a potential agricultural commodity for domestic and international markets. However, its quality is still less competitive or significantly lower to fulfill t...

    Authors: Dindin Hidayatul Mursyidin, Muhammad Irfan Makruf, Badruzsaufari and Aidi Noor
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:39
    Content type: Research Published on:
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  • ISSN: 2090-5920 (electronic)