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Journal of Genetic Engineering and Biotechnology
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  1. Ethnomedicinally important Kaempferia angustifolia is a rhizomatous aromatic herb belonging to the family Zingiberaceae. The present manuscript deals with the green synthesis of silver nanoparticles through a rap...

    Authors: Avijit Chakraborty, Sk Moquammel Haque, Diganta Dey, Swapna Mukherjee and Biswajit Ghosh
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:131
    Content type: Research Published on:

  2. Dimocarpus longan is a tropical tree that produces edible fruit. It is a neglected plant species that is listed as near threatened. In spite of its economic value, the propagation of longan cultivar using convent...

    Authors: Manal El-salato Ala El-naby Ahmed
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:130
    Content type: Research Published on:

  3. In the last 2 years, we have been fighting against SARS-CoV-2 viral infection, which continues to claim victims all over the world. The entire scientific community has been mobilized in an attempt to stop and ...

    Authors: Massimiliano Chetta, Marina Tarsitano, Maria Oro, Maria Rivieccio and Nenad Bukvic
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:129
    Content type: Research Published on:

  4. Leprosy is caused by Mycobacterium leprae and Mycobacterium lepromatosis. Most of the affected population lives in low-income countries and may take up to 10 years to show any clinical signs, which is how physic...

    Authors: Marcela Rezende Lemes, Thaís Cristina Vilela Rodrigues, Arun Kumar Jaiswal, Sandeep Tiwari, Helioswilton Sales-Campos, Leonardo Eurípedes Andrade-Silva, Carlo Jose Freire Oliveira, Vasco Azevedo, Virmondes Rodrigues, Siomar C. Soares and Marcos Vinicius da Silva
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:128
    Content type: Research Published on:

  5. Wheat is the most important cereal. One of the environmental stresses is drought that harm the production of many cereals and every year due to low rainfall and frequent droughts, the need to produce plants re...

    Authors: Sahar Shojaee, Rudabeh Ravash, Behrouz Shiran and Esmaeil Ebrahimie
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:127
    Content type: Research Published on:

  6. Primary angle-closure glaucoma (PACG) is one of the major causes of blindness in the Middle East with genetic loci and systemic oxidative stress as potential risk factors. The current case-control study aimed ...

    Authors: Marwa Aswa, Hazem Helmy, Shahira Noweir, Somaia Ismail, AlShaimaa Taha and Azza Atef
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:126
    Content type: Research Published on:

  7. Catalase (EC 1.11.1.6) is a heme-containing tetrameric enzyme that plays a critical role in signaling and hydrogen peroxide metabolism. It was the first enzyme to be crystallized and isolated. Catalase is a we...

    Authors: Takio Nene, Meera Yadav and Hardeo Singh Yadav
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:125
    Content type: Research Published on:

  8. Non-synchronized pods shattering in the Brassicaceae family bring upon huge yield losses around the world. The shattering process was validated to be controlled by eight genes in Arabidopsis, including SHP1, SHP2

    Authors: Mahideen Afridi, Khurshid Ahmad, Shahana Seher Malik, Nazia Rehman, Muhammad Yasin, Shujaul Mulk Khan, Adil Hussain and Muhammad Ramzan Khan
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:124
    Content type: Research Published on:

    The Correction to this article has been published in Journal of Genetic Engineering and Biotechnology 2022 20:139

  9. Human dental pulp-derived mesenchymal stem cells (hDP-MSCs) are a promising source of progenitor cells for bone tissue engineering. Nanocomposites made of calcium phosphate especially hydroxyapatite (HA) offer...

    Authors: Eman E. A. Mohammed, Hanan H. Beherei, Mohamed El-Zawahry, Abdel Razik H. Farrag, Naglaa Kholoussi, Iman Helwa, Mostafa Mabrouk and Alice K. Abdel Aleem
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:123
    Content type: Research Published on:

  10. Genetic factors are implicated in the progression of DR—a global cause of blindness. Hence, the current work investigated the association of HIF-1α rs11549465 and VEGF rs3025039 genetic variants with the differen...

    Authors: Mahmoud K. Mohamed, Azza A. Atef, Leqaa A. Moemen, Amira A. Abdel Azeem, Islam A. Mohalhal and Alshaimaa M. Taha
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:122
    Content type: Research Published on:

  11. The production of industrial enzymes such as xylanase using sufficient cost-effective substrates from potent microorganisms is considered economically feasible. Studies have reported castor cake (Ricinus communis

    Authors: Shaimaa A. Nour, Ghada M. El-Sayed, Hanan A. A. Taie, Maha T. H. Emam, Ahmed F. El-Sayed and Rasha G. Salim
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:121
    Content type: Research Published on:

  12. Intrinsic pathway of apoptosis is generally mediated by BCL-2 (B cell lymphoma 2) family of proteins; they either induce or inhibit the apoptosis. Overexpression of BCL-2 in cancer cell may lead to delay in ap...

    Authors: Poonam Kumari and Rashmi Rameshwari
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:120
    Content type: Research Published on:

  13. Arthrogryposis is a medical term used to describe congenital contractures which often affect multiple limbs. Distal arthrogryposis (DA) is one of the major categories of arthrogryposis that primarily affects t...

    Authors: Anik Biswas, Sudipta Deb Nath, Tamim Ahsan, M. Monir Hossain, Sharif Akhteruzzaman and Abu Ashfaqur Sajib
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:119
    Content type: Research Published on:

  14. Aeromonas veronii is one of the most common pathogens of freshwater fishes that cause sepsis and ulcers. There are increasing numbers of cases showing that it is a significant zoonotic and aquatic agent. Epidemi...

    Authors: Sk Injamamul Islam, Moslema Jahan Mou and Saloa Sanjida
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:118
    Content type: Research Published on:

  15. Interstitial lung disease (ILD) is a broad heterogeneous group of lung disorders that is characterized by inflammation of the lungs. Surfactant dysfunction disorders are a rare form of ILD diseases that result...

    Authors: Azza K. Abdel Megeid, Miral M. Refeat, Engy A. Ashaat, Ghada El-Kamah, Sonia A. El-Saiedi, Mona M. Elfalaki, Mona O. El Ruby and Khalda S. Amr
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:117
    Content type: Research Published on:

    The Correction to this article has been published in Journal of Genetic Engineering and Biotechnology 2022 20:137

  16. Capsicum or chilli is an important crop in India which exhibits immense structural and genetic variations reflecting their intra- and inter-specific relationships. The aim of this study was to establish relations...

    Authors: Shamshadul Haq, Shikha Dubey, Prerna Dhingra, Kumar Sambhav Verma, Deepa Kumari, S. L. Kothari and Sumita Kachhwaha
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:116
    Content type: Research Published on:

  17. Nowadays, the conventional plastic wastes are very challenging to environments and its production cost also creates an economic crisis due to petrochemical-based plastic. In order to solve this problem, the cu...

    Authors: Seid Mohammed and Lopamudra Ray
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:115
    Content type: Research Published on:

    The Correction to this article has been published in Journal of Genetic Engineering and Biotechnology 2022 20:138

  18. The X-chromosome short tandem repeat (STR) polymorphisms are a particular tool in the fields of human population genetics and personal identification. It was necessary in investigating complex kinship or defic...

    Authors: Salwa J. Al-Awadi, Hayder A. Khaleefah and Shaimaa Y. Abdulfattah
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:114
    Content type: Research Published on:

  19. Endophytic bacteria overlay significant role in plant growth promotion, eliminating phyto-pathogens and combating stress-conditions. In the present study, we aimed to screen high salt tolerant bacteria and stu...

    Authors: Namita Bhutani, Rajat Maheshwari, Nidhi Sharma, Pradeep Kumar, Amita Suneja Dang and Pooja Suneja
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:113
    Content type: Research Published on:

  20. The prenatal diagnosis of syndromes caused by chromosomal abnormality is a long-established part of obstetric care. Several DNA-based molecular approaches have provided rapid prenatal diagnosis of of cytogenom...

    Authors: Ola M. Eid, Maha M. Eid, Marwa Farid, Rania M. A. Abdel Kader, Rana Mahrous and Sara H. El-Dessouky
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:112
    Content type: Research Published on:

  21. The production of monoclonal antibodies for immunoglobulin detection is not cost-effective, while polyclonal antibody production depends on laboratory animals, raising concerns on animal welfare. The widesprea...

    Authors: Anelize Felicio Ramos, Leonardo Antônio Fernandes, Franciane Batista, Bianca de Souza Vieira, Mayerson Thompson, Jacó Joaquim Mattos, Maria Risoleta Freire Marques, Maria de Lourdes Borba Magalhães and Gustavo Felippe da Silva
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:111
    Content type: Research Published on:

  22. This study aimed to explore the association between polymorphisms in three genes: leptin (LEP), leptin receptor (LEPR), and BMP4, and incidence of repeat breeding in Egyptian buffaloes.

    Authors: Karima F. Mahrous, Heba A. M. Abd El -Kader, Mohamad A. Abdelhafez, Mohamad M. Aboelenin, Esraa A. Balabel, Dalia M. Mabrouk, Osama M. EL Malky and Mohamed S. Hassanane
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:110
    Content type: Research Published on:

  23. Global food supply is highly dependent on field crop production that is currently severely threatened by changing climate, poor soil quality, abiotic, and biotic stresses. For instance, one of the major challe...

    Authors: Simon W. Mburu, Gilbert Koskey, Ezekiel M. Njeru, Omwoyo Ombori, John Maingi and Jacinta M. Kimiti
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:109
    Content type: Research Published on:

  24. COVID-19 has become a pandemic, and any new drug for treating the disease could save millions of lives. Several drugs already in use for other diseases and medical conditions are repurposed for treating COVID-...

    Authors: Sellappan Mohan, Jayagopal Dharani, Ramanathan Natarajan and Arumugam Nagarajan
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:108
    Content type: Research Published on:

  25. The present study was designed to develop an improved in vitro regeneration system for Dioscorea bulbifera using mature nodal explants. Direct organogenesis from nodal segments was achieved by culturing the nodal...

    Authors: Musadiq Hussain Bhat, Mufida Fayaz, Amit Kumar, Alamgir A. Dar and Ashok Kumar Jain
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:107
    Content type: Research Published on:

  26. In recent years, major advance in molecular biology and genomic technologies have led to an exponential growth in biological information. As the deluge of genomic information, there is a parallel growth in the...

    Authors: Yung Cheng Tan, Asqwin Uthaya Kumar, Ying Pei Wong and Anna Pick Kiong Ling
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:106
    Content type: Review Published on:

  27. Citrus species are among the most important and widely consumed fruit trees in the world and are subjected to increasing global cultivation. Sweet orange (Citrus sinensis L. Osbeck) is one of 30 species of citrus...

    Authors: Narineh Shahnazari, Zahra Noormohammadi, Masoud Sheidai and Fahimeh Koohdar
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:105
    Content type: Research Published on:

  28. DNA damage and genome instability in host cells are introduced by many viruses during their life cycles. Severe acute respiratory syndrome coronaviruses (SARS-CoVs) manipulation of DNA damage response (DDR) is...

    Authors: Asmaa S. Mekawy, Zina Alaswad, Aya A. Ibrahim, Ahmed A. Mohamed, Abdelrahman AlOkda and Menattallah Elserafy
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:104
    Content type: Review Published on:

  29. Small RNAs (sRNAs) that do not get untranslated into proteins exhibit a pivotal role in the expression regulation of their cognate gene(s) in almost all eukaryotic lineages, including plants. Hitherto, numerou...

    Authors: Behzad Hajieghrari, Naser Farrokhi and Mojahed Kamalizadeh
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:103
    Content type: Research Published on:

  31. Plants use escape strategies including premature senescence and leaf reduction to cope in response to drought stress, which in turn reduces plant leaves and photosynthesis. This strategy allows the new generat...

    Authors: Zohreh Hajibarat and Abbas Saidi
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:101
    Content type: Review Published on:

  32. Burkholderia pseudomallei is an infectious agent causing severe disease melioidosis resulting in pneumonia, fever, and acute septicemia in humans. B. pseudomallei show resistance to drugs. No such FDA-approved va...

    Authors: Muhammad Shahab, Chandni Hayat, Ramin Sikandar, Guojun Zheng and Shahina Akter
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:100
    Content type: Research Published on:

  33. The freshwater snails Biomphalaria alexandrina (Gastropoda: Planorbidae) has public health importance of being an intermediate host of Schistosoma mansoni, the parasite species that causes intestinal schistosomia...

    Authors: Abdel-Monem Abdalla and Ghada S. A. Abdel Karim
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:99
    Content type: Research Published on:

  34. The baculovirus expression vector system has been developed for expressing a wide range of proteins, including enzymes, glycoproteins, recombinant viruses, and vaccines. The availability of the SARS-CoV-2 geno...

    Authors: Muhammad Azharuddin Azali, Salmah Mohamed, Azian Harun, Faezahtul Arbaeyah Hussain, Shaharum Shamsuddin and Muhammad Farid Johan
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:98
    Content type: Review Published on:

  35. Preferentially expressed antigen of melanoma (PRAME) gene is regularly overexpressed in acute leukemia (AL) and other malignant diseases which are recognized by human leucocyte antigen (HLA-24) located in the ...

    Authors: Nagaraj V. Kulkarni, Reshma A. Shetty, Suchetha Kumari N, Vijith V. Shetty, Rajesh Krishna, Meenakshi Arumugam, Akanksha A. Kalal and Prashanth Shetty
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:97
    Content type: Research Published on:

  36. Gaining insight into crop diversity, both at the genetic and phenotypic levels, is of prime importance for onion breeding with an enhanced yield and quality in combination with improved resistance to biotic an...

    Authors: Amal Brahimi, Sofie Landschoot, Boris Bekaert, Lhoussain Hajji, Hassan Hajjaj, Kris Audenaert, Geert Haesaert and Hamid Mazouz
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:96
    Content type: Research Published on:

  37. Mastitis is an inflammation of the mammary glands caused by a microbial infection. The common bacteria causing this infection in dairy farms are Staphylococcus aureus, Streptococcus agalactiae, and Escherichia co...

    Authors: Arizah Kusumawati, Apon Zaenal Mustopa, I. Wayan Teguh Wibawan, Agus Setiyono and Mirnawati Bachrum Sudarwanto
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:95
    Content type: Research Published on:

  39. Synthesized gallium nanoparticles synthesized by grape seed extract were characterized with spherical shape and size range less than100 nm, possessing the functional groups of the biological material. The purp...

    Authors: Mohga S. Abdalla, El-Sayed M. El-Mahdy, Somaya Z. Mansour, Sawsan M. Elsonbaty and Menna H. Amin
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:93
    Content type: Research Published on:

  40. Single-nucleotide polymorphisms (SNPs) have a crucial function in affecting the susceptibility of individuals to diseases and also determine how an individual responds to different treatment options. The prese...

    Authors: Harini Venkata Subbiah, Polani Ramesh Babu and Usha Subbiah
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:92
    Content type: Research Published on:

  41. The utilization of bioluminescent bacteria in environmental monitoring of water contaminates considers being a vital and powerful approach. This study aimed to isolate, optimize, and apply luminescent bacteria...

    Authors: Howaida Hassan, Marwa Eltarahony, Gadallah Abu-Elreesh, Hanan M. Abd-Elnaby, Soraya Sabry and Hanan Ghozlan
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:91
    Content type: Research Published on:

  42. Owing to its remarkable mechanical properties that surpass the plant-based cellulose, bacterial cellulose production has been targeted for commercialization during the last few years. However, the large-scale ...

    Authors: Saif S. Al-Janabi, Heba Shawky, Amr A. El-Waseif, Ayman A. Farrag, Tarek M. Abdelghany and Dina E. El-Ghwas
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:90
    Content type: Research Published on:

  43. Bunyumwera virus can cause 82% mortality in humans currently with no vaccine or drugs for treatment. We described an in silico multi-epitope vaccine targeting Bunyumwera virus nucleocapsid N-protein and predic...

    Authors: Kanaka Durga Devi Nelluri, Manne Anupama Ammulu, M. Lakshmi Durga, Melika Sravani, Vemuri Praveen Kumar and Sudhakar Poda
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:89
    Content type: Research Published on:

  44. In seek of potent and non-toxic iminoguanidine derivatives formerly assessed as active Pseudomonas aeruginosa inhibitors, a combined mathematical approach of quantitative structure-activity relationship (QSAR)...

    Authors: Emmanuel Israel Edache, Adamu Uzairu, Paul Andrew Mamza and Gideon Adamu Shallangwa
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:88
    Content type: Research Published on:

  45. Lignocellulosic biomasses produced from agriculture and forest-based industries are the cheapest or negative-cost biomass with a great potential for biotransformation to value-added bioproducts. Paper mill slu...

    Authors: Tuhin Das, Ferdausi Ali and Md. Shafiqur Rahman
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:87
    Content type: Research Published on:

  46. Aegilops tauschii Coss. as a donor of wheat D genome has an important role in wheat breeding programs. Genetic and phylogeographic diversity of 79 Ae. tauschii accessions collected from north and northwest of Ira...

    Authors: Sona Minaei, Seyyed Abolghasem Mohammadi, Atefeh Sabouri and Ahmad Reza Dadras
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:86
    Content type: Research Published on:

  47. This study was designed to generate functional insulin-producing cells (IPCs) from dental-derived mesenchymal stem cells (MSCs) and further explore their therapeutic potential against diabetes mellitus in vivo...

    Authors: Riham M. Aly, Hadeer A. Aglan, Ghada Nour Eldeen, Nadia S. Mahmoud, Eman H. Aboul-Ezz and Hanaa H. Ahmed
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:85
    Content type: Research Published on:

  48. Fibroblast growth factor 21 (FGF-21), alpha-amylase, and alpha-glucosidase are key proteins implicated in metabolic dysregulations. Bisphenol A (BPA) is an environmental toxicant known to cause endocrine dysre...

    Authors: P. M. Aja, J. N. Awoke, P. C. Agu, A. E. Adegboyega, E. M. Ezeh, I. O. Igwenyi, O. U. Orji, O. G. Ani, B. A. Ale and U. A. Ibiam
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:84
    Content type: Research Published on:

  49. Schizophrenia is a chronic mental disorder with different symptoms. The environmental and genetic factors are suggested to be the etiology of schizophrenia. However, the exact cause and pathogenesis of schizop...

    Authors: Maged Mostafa, Aya Ahmed Fathy, Mohamed Elwasify and Maha Abdelsalam
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:83
    Content type: Research Published on:

  50. Protease is one of the most important industrial enzymes. The importance of protease bioproduction comes from meeting the increasing demand for this enzyme especially in the cheese industry. Rhizomucor miehei pro...

    Authors: Houthail Alahmad Aljammas, Sabah Yazji and Abdulhakim Azizieh
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:82
    Content type: Research Published on:
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  • ISSN: 2090-5920 (electronic)