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Journal of Genetic Engineering and Biotechnology
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  1. Sanger dideoxy sequencing is vital in clinical analysis due to its accuracy, ability to analyze genetic markers like SNPs and STRs, capability to generate reliable DNA profiles, and its role in resolving compl...

    Authors: Mohammed Baqur S. Al-Shuhaib and Hayder O. Hashim
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:115
    Content type: Review Published on:

  2. Asthma is a chronic and complex pulmonary condition that affects the airways. A total of 250,000 asthma-related deaths are recorded annually and several proteins including chymase, spleen tyrosine kinase, and ...

    Authors: Precious Ayorinde Akinnusi, Samuel Olawale Olubode, Ayomide Oluwadarasimi Adebesin, Adebowale Abiodun Alade, Victor Chinedu Nwoke and Sidiqat Adamson Shodehinde
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:113
    Content type: Research Published on:

  3. One of the 11 recognized mucopolysaccharidosis (MPS) diseases is Sanfilippo. It is autosomal recessive in its mode of transmission. There are four subtypes of Sanfilippo (A, B, C, and D). The most worldwide pr...

    Authors: Soha S. Nosier, Seham M. S. El Nakeeb, Mona M. Ibrahim, Mona El-Gammal and Ekram M. Fateen
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:112
    Content type: Research Published on:

  4. The deletions of azoospermic factor regions (AZF) are considered risk factor of spermatogenic failure. AZF duplications or complex copy number variants (CNVs) were rarely studied because STS-PCR could not alwa...

    Authors: Maha M. Eid, Ola M. Eid, Amany H. Abdelrahman, Islam F. S. Abdelrahman, Elshaimaa A. F. Aboelkomsan, Rania M. A. AbdelKader, Mirhane Hassan, Marwa Farid, Alshaymaa A. Ibrahim, Safa N. Abd El-Fattah and Rana Mahrous
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:111
    Content type: Research Published on:

  5. Nitrogen is one of the most important mineral nutrients for plants and is absorbed by the root system mainly in the inorganic form (NH+4 and NO−3). Plants absorb nitrogen as a food source for growth, biomass prod...

    Authors: Zohreh Hajibarat, Abbas Saidi, Habibollah Ghazvini and Zahra Hajibarat
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:110
    Content type: Research Published on:

  6. Obesity is one of the most serious problems over the world. MicroRNAs have developed as main mediators of metabolic processes, playing significant roles in physiological processes. Thus, the present study aime...

    Authors: Weaam Gouda, Amr E. Ahmed, Lamiaa Mageed, Amgad K. Hassan, Mie Afify, W. I. Hamimy, Halla M. Ragab, Nabila Abd El Maksoud, Abdou K. Allayeh and Mohamed D. E. Abdelmaksoud
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:109
    Content type: Research Published on:

  7. Cryptococcus neoformans is a fungal pathogen that can cause serious meningoencephalitis in individuals with compromised immune systems due to HIV/AIDS (human immunodeficiency virus/acquired immunodeficiency syndr...

    Authors: Amir Elalouf and Amit Yaniv-Rosenfeld
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:108
    Content type: Research Published on:

  8. The bleach-boosting capability of xylanases is well-known. The use of xylanase pre-treatment before the application of chemical bleach has multiple advantages including (i) lesser use of polluting chemicals of...

    Authors: Girisha Malhotra and Shilpa S. Chapadgaonkar
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:107
    Content type: Research Published on:

  9. The quick and accurate identification of viruses is essential for plant disease management. Next-generation sequencing (NGS) technology may allow the discovery, detection, and identification of plant pathogens...

    Authors: Esraa A. Elwan, Mona Rabie, Engy E. Abdel Aleem, Faiza A. Fattouh, Meenakshi S. Kagda and Heba A. H. Zaghloul
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:106
    Content type: Research Published on:

  10. Microsatellites are important markers for livestock including ducks. The development of microsatellites is expensive and labor-intensive. Meanwhile, the in silico approach for mining for microsatellites became...

    Authors: Hosam Safaa, Rawan Khaled, Suzy Isaac, Rofida Mostafa, Mohamed Ragab, Dalia A. A. Elsayed and Mostafa Helal
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:105
    Content type: Research Published on:

  11. Phylogenetic inference is an important approach that allows the recovery of the evolutionary history and the origin of the Chlorellaceae species. Despite the species’ potential for biofuel feedstock production...

    Authors: Ee Bhei Wong, Nurhaida Kamaruddin, Marina Mokhtar, Norjan Yusof and Raja Farhana R. Khairuddin
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:104
    Content type: Short Communications Published on:

  12. Factor C (FC) is widely used as a standard material for endotoxin testing. It functions as a zymogenic serine protease and serve as a biosensor that detects lipopolysaccharides. Prior investigations involving ...

    Authors: Zubaidi Bachtiar, Apon Zaenal Mustopa, Rika Indri Astuti, Fauziyah Fauziyah, Fatimah Fatimah, Rozirwan Rozirwan, Tuah Nanda Merlia Wulandari, Dina Permata Wijaya, Fitri Agustriani, Arwansyah Arwansyah, Herman Irawan and Jendri Mamangkey
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:103
    Content type: Research Published on:

  13. Soybean mosaic virus (SMV) is a devastating disease that threatens soybean plants worldwide. The different soybean genotypes displayed different responses to SMV strains. This study aimed to investigate the re...

    Authors: Mohammed A. Eid, Gehan N. Momeh, Abd El-Raheem R. El-Shanshoury, Nanis G. Allam and Reda M. Gaafar
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:102
    Content type: Research Published on:

  15. Staphylococcus aureus spreads its infections through biofilms. This usually happens in the stationary phase of S. aureus growth where it utilizes accumulated acetate as a carbon source via the phosphotrans-acetyl...

    Authors: Subbarayudu Suthi, A. Mounika and Venkata Gurunadha Krishna Sarma Potukuchi
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:100
    Content type: Research Published on:

  16. Bovine Tuberculosis is a respiratory disease caused by the pathogen Mycobacterium bovis (M. bovis) that infects cattle. Though rare, this disease can also affect humans, as well as domestic and wild animals, maki...

    Authors: Zhandos Abay, Sandugash Sadikalieva, Kamshat Shorayeva, Bolat Yespembetov, Makpal Sarmykova, Kuanish Jekebekov, Gaukhar Tokkarina, Zharkinay Absatova, Elina Kalimolda, Yeraly Shayakhmetov, Sabina Moldagulova, Aisha Issabek, Syrym Kopeyev, Alisher Omurtay, Kainar Barakbayev, Markhabat Kassenov…
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:99
    Content type: Short Communications Published on:

  18. Multidrug-resistant (MDR) bacteria are acknowledged as one of the main factors contributing to chronic illnesses and fatalities globally. Numerous diseases, including bloodstream infections, pneumonia, urinary...

    Authors: Mohamad Abdelrazik, Hassan H. Elkotaby, Abdullah Yousef, Ahmed F. El-Sayed and Mohamed Khedr
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:97
    Content type: Research Published on:

  19. Indonesian local rabbit (Oryctolagus cuniculus) is a local breed in Indonesia. We reveal the mitochondrial genome sequence of the Indonesian local Rabbit for the first time. A better understanding of the mechanis...

    Authors: Asep Setiaji, Dela Ayu Lestari, Nuruliarizki Shinta Pandupuspitasari, Ikania Agusetyaningsih and Faheem Ahmed Khan
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:96
    Content type: Research Published on:

  20. Tuftelin 1 (TUFT1) gene is important in the development and mineralization of dental enamel. The study aimed to identify potential functionally deleterious non-synonymous SNPs (nsSNPs) in the TUFT1 gene by using ...

    Authors: Athira Ajith and Usha Subbiah
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:95
    Content type: Research Published on:

  21. Vibrio species are among the autochthonous bacterial  populations found in surface waters and associated with various life-threatening extraintestinal diseases, especially in human populations with underlying ill...

    Authors: Hope Onohuean and Uchechukwu U. Nwodo
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:94
    Content type: Research Published on:

  22. Since effective antiviral drugs for COVID-19 are still limited in number, the exploration of compounds that have antiviral activity against SARS-CoV-2 is in high demand. Porphyrin is potentially developed as a...

    Authors: Azzania Fibriani, Audrey Angelina Putri Taharuddin, Nicholas Yamahoki, Rebecca Stephanie, Jessica Laurelia, Dian Fitria Agustiyanti, Popi Hadi Wisnuwardhani, Marissa Angelina, Yana Rubiyana, Ratih Asmana Ningrum, Andri Wardiana, Desriani Desriani, Ferry Iskandar, Fitri Aulia Permatasari and Ernawati Arifin Giri-Rachman
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:93
    Content type: Research Published on:

  23. Tecothane (medical grade of polyurethane) is strongly involved in the fabrication of metallic and polymeric-based medical devices (e.g., catheters and stents) as they can withstand cardiac cycle-related forces...

    Authors: Reham G. Elfarargy, Mohamed Sedki, Farag A. Samhan, Rabeay Y. A. Hassan and Ibrahim M. El-Sherbiny
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:92
    Content type: Research Published on:

  24. Euphorbia resinifera is a melliferous, medicinal, and endemic plant to Morocco. Nevertheless, its ecological and genetic diversity still unknown. The objective of this study is to analyze the diversity and geneti...

    Authors: Hassane Abd-dada, Said Bouda, Youssef Khachtib, Youssef Ait Bella and Abdelmajid Haddioui
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:91
    Content type: Research Published on:

  25. Drug-resistant  Tuberculosis (DR-TB) is a global health burden with high morbidity and mortality in developing countries including Egypt. The susceptibility to infection with DR-TB strains may be genetically d...

    Authors: Asmaa A. Elmadbouly, Abeer Mohammed Abdul-Mohymen, Heba H. Eltrawy, Hanaa A. Abou Elhasan, Azza Ali Althoqapy and Doaa R. Amin
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:90
    Content type: Research Published on:

  26. Predictors of chronic HCV response to oral antiviral therapy (OAT) are related to host genetic variations. Single nucleotide polymorphisms (SNP) and alleles variations of host genes in association with hepatic...

    Authors: Al-Shazly Gaber Mohamed Galal, Reham M. Dawood, Mostafa K. El Awady, Yasser Mohamed Mohamed El-Dessouky, Mohamed Mahmoud Abdel-Halim Mahmoud and Mohamed Darwish Ahmed Abd Alla
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:89
    Content type: Research Published on:

  27. New-generation sequencing (NGS) techniques have brought the opportunity for genomic monitoring of several microorganisms potentially relevant to public health. The establishment of different methods with diffe...

    Authors: Leandro Menezes de Souza, Isabelle Dias de Oliveira, Flávia Cristina Silva Sales, Antonio Charlys da Costa, Karoline Rodrigues Campos, Adriano Abbud, Juliana Mariotti Guerra, Cinthya dos Santos Cirqueira Borges, Carlos Pires Fernandes Júnior Takahashi and Leonardo José Tadeu de Araújo
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:88
    Content type: Research Published on:

  28. Polycystic ovary syndrome is a common multifactorial endocrinopathy disorder affecting 5–15% of reproductive women worldwide. The CYP19 gene encodes key enzyme aromatase involved in androgen-to-estrogen conver...

    Authors: Pravesh Hegde, Shilpa S. Shetty, Prasanna Kumar Shetty, Lakshmi Manjeera, D. Prashanth Shetty and Suchetha Kumari
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:87
    Content type: Research Published on:

  29. It is important to comprehend how the molecular mechanisms shift when gastric cancer in its early stages (GC). We employed integrative bioinformatics approaches to locate various biological signalling pathways...

    Authors: Tamizh G. Selvan, Pavan Gollapalli, Santosh H. S. Kumar and Sudeep D. Ghate
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:86
    Content type: Research Published on:

  30. Up to date, a well-defined microRNAs (miRNAs) profile involved in hepatocellular carcinoma (HCC) pathogenesis remains indecisive. Thus, employing miRNAs for HCC diagnosis is demanded for early therapeutic inte...

    Authors: Sara M. Abdo, Wafaa Gh. Shousha, Amal Ahmed Mohamed, Mohamed Elshobaky, Mohamed Saleh and Mostafa Mohamed Abdelhamid Ali
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:85
    Content type: Research Published on:

  31. Soil metagenomics is a cultivation-independent molecular strategy for investigating and exploiting the diversity of soil microbial communities. Soil microbial diversity is essential because it is critical to s...

    Authors: Usha Chouhan, Umesh Gamad and Jyoti Kant Choudhari
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:84
    Content type: Research Published on:

  32. Myogenic enhancer transcription factor 2A (MEF2A) is a transcription factor known for its role in controlling skeletal muscle regeneration and metabolic processes, while activating transcription factor 3 (ATF3...

    Authors: Alfan Kurniawan, Muhammad Halim Natsir, Suyadi Suyadi, Osfar Sjofjan, Yuli Frita Nuningtyas, Ari Ardiantoro, Ahmad Furqon and Suci Puji Lestari
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:83
    Content type: Research Published on:

  33. Human nucleotide triphosphate diphosphatase (NUDT15) is one of the essential proteins involved in the hydrolysis of anti-cancer drugs against leukemia. Polymorphisms in NUDT15 significantly affect the hydrolys...

    Authors: Janakiraman V., Sudhan M., Khalaf F. Alsharif, Ibrahim F. Halawani, Shiek S. S. J. Ahmed and Shankargouda Patil
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:82
    Content type: Research Published on:

  34. About one-third of patients with estrogen receptor alpha (ERα)-positive breast cancer have tumors which are progesterone receptor (PR) negative. PR is an important prognostic factor in breast cancer. Patients ...

    Authors: Mariana Bustamante Eduardo, Irene Keller, Nathalie Schuster, Stefan Aebi and Rolf Jaggi
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:81
    Content type: Research Published on:

  35. The Pavo cristatus population, native to the Indian subcontinent, is thriving well in India. However, the Pavo muticus population, native to the tropical forests of Southeast Asia, has reduced drastically and has...

    Authors: Shahla Yasmin, Sushant Kumar and Gajendra Kumar Azad
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:80
    Content type: Research Published on:

  36. Colorectal Cancer (CRC) is the third most common cancer type and the second leading cause of cancer-related deaths worldwide. However, the existing treatment, as well as prognosis strategies for CRC patients, ...

    Authors: Mutebi John Kenneth, Tushar Ahmed Shishir and Fahim Kabir Monjurul Haque
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:79
    Content type: Research Published on:

  37. Tubulins are highly conserved globular proteins involved in stabilization of cellular cytoskeletal microtubules during cell cycle. Different isoforms of tubulins are differentially expressed in various cell ty...

    Authors: Polani B. Ramesh Babu
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:78
    Content type: Research Published on:

  38. Sheep is one of the commodities of livestock which has been known widely in Indonesia for supporting the national food security. Improvement in genetic quality by selection based on genetic markers for growth ...

    Authors: Puruhita, Ronny Rachman Noor, Endang Tri Margawati and Herman W. Raadsma
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:77
    Content type: Research Published on:

  39. Exopolysaccharides are extremely powerful molecules with a wide range of uses in pharmaceuticals due to their structural and compositional complexity. Marine microorganisms often produce bioactive substances w...

    Authors: Manal G. Mahmoud, Mohamed E. El Awady, Manal S. Selim, Abeer Y. Ibrahim, Faten M. Ibrahim and Sahar S. Mohamed
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:76
    Content type: Research Published on:

  40. Cancer is a major issue in medical science with increasing death cases every year worldwide. Therefore, searching for alternatives and nonorthodox methods of treatments with high efficiency, selectivity and le...

    Authors: Saja A. Ahmed, Ahmed F. Al-Shanon, Ali Z. Al-Saffar, Alene Tawang and Jameel R. Al-Obaidi
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:75
    Content type: Research Published on:

  41. The MYB family is one of the most significant groups of transcription factors in plants. However, several MYBs have been linked to secondary metabolism and are important for determining the color of fruit’s pe...

    Authors: Israr Ahmad, Sumit K. Soni, Muthukumar M. and Devendra Pandey
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:74
    Content type: Research Published on:

  42. Wild relatives of wheat are one of the most important genetic resources to use in wheat breeding programs. Therefore, identifying wild relatives of wheat and being aware of their diversity, is undeniably effec...

    Authors: Maryam Jabari, Ahmadreza Golparvar, Behzad Sorkhilalehloo and Majid Shams
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:73
    Content type: Research Published on:

  43. Due to the advantages of molecular methods over biochemical methods, the use of molecular methods for diagnosing nosocomial infections such as Pseudomonas can be an appropriate and rapid way to choose the right d...

    Authors: Zahra Mousivand, Fatemeh Haddadi and Hossein Kamaladini
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:72
    Content type: Research Published on:

  44. The forming, blending, and characterization of materials at a size of one billionth of a meter or less is referred to as nanotechnology. The objective of the current study was to synthesize ecologically friend...

    Authors: Krishnakumari N. Patel, Pooja G. Trivedi, Milan S. Thakar, Kush V. Prajapati, Dhruv K. Prajapati and Gaurang M. Sindhav
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:71
    Content type: Research Published on:

  45. Thottea siliquosa (Lamk.) Ding Hou., an important medicinal shrub, is widely used in both ayurvedic and indigenous systems of medicine. Root being the most useful part, the plant is constantly uprooted and thus p...

    Authors: Chandran Padikkal Krishna Vrundha and Thuruthiyil Dennis Thomas
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:70
    Content type: Research Published on:

  46. The root system is vital to plant growth and survival. Therefore, genetic improvement of the root system is beneficial for developing stress-tolerant and improved plant varieties. This requires the identificat...

    Authors: Samadhi S. Wimalagunasekara, Janith W. J. K. Weeraman, Shamala Tirimanne and Pasan C. Fernando
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:69
    Content type: Research Published on:

  47. Vaccination is the one of the agendas of many countries to reduce cervical cancer caused by the Human papillomavirus. Currently, VLP-based vaccine is the most potent vaccine against HPV, which could be produce...

    Authors: Moh Egy Rahman Firdaus, Apon Zaenal Mustopa, Nurlaili Ekawati, Sheila Chairunnisa, Rosyida Khusniatul Arifah, Ai Hertati, Shasmita Irawan, Anika Prastyowati, Arizah Kusumawati and Maritsa Nurfatwa
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:68
    Content type: Research Published on:

  48. Date palm, oasis pivot, plays a vital socio-economic part in the southern area of Morocco. However, with climate change and drought intensity and frequency increasing, the Moroccan palm grove is threatened wit...

    Authors: Maha Ibrahimi, Najiba Brhadda, Rabea Ziri, Mohamed Fokar, Driss Iraqi, Fatima Gaboun, Mustapha Labhilili, Aicha Habach, Reda Meziani, Jamal Elfadile, Rabha Abdelwahd and Ghizlane Diria
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:66
    Content type: Research Published on:

  49. Human insulin was the first FDA-approved biopharmaceutical drug produced through recombinant DNA technology. The previous studies successfully expressed recombinant human insulin precursors (HIP) in Pichia pastor...

    Authors: Nuruliawaty Utami, Dini Nurdiani, Hariyatun Hariyatun, Eko Wahyu Putro, Fadillah Putri Patria and Wien Kusharyoto
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:67
    Content type: Research Published on:

  50. SARS-CoV-2 infection involves disturbing multiple molecular pathways related to immunity and cellular functions. PIM1 is a serine/threonine-protein kinase found to be involved in the pathogenesis of several vi...

    Authors: Magda M. F. Ismail, Rehab R. El-Awady, Amal M. Farrag, Sara H. Mahmoud, Noura M. Abo Shama, Ahmed Mostafa, Mohamed A. Ali, Mohammed H. Rashed and Iman H. Ibrahim
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:65
    Content type: Research Published on:

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2022 Citation Impact
3.5 - 2-year Impact Factor
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  • ISSN: 2090-5920 (electronic)