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  1. Global food supply is highly dependent on field crop production that is currently severely threatened by changing climate, poor soil quality, abiotic, and biotic stresses. For instance, one of the major challe...

    Authors: Simon W. Mburu, Gilbert Koskey, Ezekiel M. Njeru, Omwoyo Ombori, John Maingi and Jacinta M. Kimiti
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:109
  2. COVID-19 has become a pandemic, and any new drug for treating the disease could save millions of lives. Several drugs already in use for other diseases and medical conditions are repurposed for treating COVID-...

    Authors: Sellappan Mohan, Jayagopal Dharani, Ramanathan Natarajan and Arumugam Nagarajan
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:108
  3. The present study was designed to develop an improved in vitro regeneration system for Dioscorea bulbifera using mature nodal explants. Direct organogenesis from nodal segments was achieved by culturing the nodal...

    Authors: Musadiq Hussain Bhat, Mufida Fayaz, Amit Kumar, Alamgir A. Dar and Ashok Kumar Jain
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:107
  4. In recent years, major advance in molecular biology and genomic technologies have led to an exponential growth in biological information. As the deluge of genomic information, there is a parallel growth in the...

    Authors: Yung Cheng Tan, Asqwin Uthaya Kumar, Ying Pei Wong and Anna Pick Kiong Ling
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:106
  5. Citrus species are among the most important and widely consumed fruit trees in the world and are subjected to increasing global cultivation. Sweet orange (Citrus sinensis L. Osbeck) is one of 30 species of citrus...

    Authors: Narineh Shahnazari, Zahra Noormohammadi, Masoud Sheidai and Fahimeh Koohdar
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:105
  6. DNA damage and genome instability in host cells are introduced by many viruses during their life cycles. Severe acute respiratory syndrome coronaviruses (SARS-CoVs) manipulation of DNA damage response (DDR) is...

    Authors: Asmaa S. Mekawy, Zina Alaswad, Aya A. Ibrahim, Ahmed A. Mohamed, Abdelrahman AlOkda and Menattallah Elserafy
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:104
  7. Small RNAs (sRNAs) that do not get untranslated into proteins exhibit a pivotal role in the expression regulation of their cognate gene(s) in almost all eukaryotic lineages, including plants. Hitherto, numerou...

    Authors: Behzad Hajieghrari, Naser Farrokhi and Mojahed Kamalizadeh
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:103
  8. Plants use escape strategies including premature senescence and leaf reduction to cope in response to drought stress, which in turn reduces plant leaves and photosynthesis. This strategy allows the new generat...

    Authors: Zohreh Hajibarat and Abbas Saidi
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:101
  9. Burkholderia pseudomallei is an infectious agent causing severe disease melioidosis resulting in pneumonia, fever, and acute septicemia in humans. B. pseudomallei show resistance to drugs. No such FDA-approved va...

    Authors: Muhammad Shahab, Chandni Hayat, Ramin Sikandar, Guojun Zheng and Shahina Akter
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:100
  10. The freshwater snails Biomphalaria alexandrina (Gastropoda: Planorbidae) has public health importance of being an intermediate host of Schistosoma mansoni, the parasite species that causes intestinal schistosomia...

    Authors: Abdel-Monem Abdalla and Ghada S. A. Abdel Karim
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:99
  11. The baculovirus expression vector system has been developed for expressing a wide range of proteins, including enzymes, glycoproteins, recombinant viruses, and vaccines. The availability of the SARS-CoV-2 geno...

    Authors: Muhammad Azharuddin Azali, Salmah Mohamed, Azian Harun, Faezahtul Arbaeyah Hussain, Shaharum Shamsuddin and Muhammad Farid Johan
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:98
  12. Preferentially expressed antigen of melanoma (PRAME) gene is regularly overexpressed in acute leukemia (AL) and other malignant diseases which are recognized by human leucocyte antigen (HLA-24) located in the ...

    Authors: Nagaraj V. Kulkarni, Reshma A. Shetty, Suchetha Kumari N, Vijith V. Shetty, Rajesh Krishna, Meenakshi Arumugam, Akanksha A. Kalal and Prashanth Shetty
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:97
  13. Gaining insight into crop diversity, both at the genetic and phenotypic levels, is of prime importance for onion breeding with an enhanced yield and quality in combination with improved resistance to biotic an...

    Authors: Amal Brahimi, Sofie Landschoot, Boris Bekaert, Lhoussain Hajji, Hassan Hajjaj, Kris Audenaert, Geert Haesaert and Hamid Mazouz
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:96
  14. Mastitis is an inflammation of the mammary glands caused by a microbial infection. The common bacteria causing this infection in dairy farms are Staphylococcus aureus, Streptococcus agalactiae, and Escherichia co...

    Authors: Arizah Kusumawati, Apon Zaenal Mustopa, I. Wayan Teguh Wibawan, Agus Setiyono and Mirnawati Bachrum Sudarwanto
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:95
  15. Synthesized gallium nanoparticles synthesized by grape seed extract were characterized with spherical shape and size range less than100 nm, possessing the functional groups of the biological material. The purp...

    Authors: Mohga S. Abdalla, El-Sayed M. El-Mahdy, Somaya Z. Mansour, Sawsan M. Elsonbaty and Menna H. Amin
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:93
  16. Single-nucleotide polymorphisms (SNPs) have a crucial function in affecting the susceptibility of individuals to diseases and also determine how an individual responds to different treatment options. The prese...

    Authors: Harini Venkata Subbiah, Polani Ramesh Babu and Usha Subbiah
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:92
  17. The utilization of bioluminescent bacteria in environmental monitoring of water contaminates considers being a vital and powerful approach. This study aimed to isolate, optimize, and apply luminescent bacteria...

    Authors: Howaida Hassan, Marwa Eltarahony, Gadallah Abu-Elreesh, Hanan M. Abd-Elnaby, Soraya Sabry and Hanan Ghozlan
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:91
  18. Owing to its remarkable mechanical properties that surpass the plant-based cellulose, bacterial cellulose production has been targeted for commercialization during the last few years. However, the large-scale ...

    Authors: Saif S. Al-Janabi, Heba Shawky, Amr A. El-Waseif, Ayman A. Farrag, Tarek M. Abdelghany and Dina E. El-Ghwas
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:90
  19. Bunyumwera virus can cause 82% mortality in humans currently with no vaccine or drugs for treatment. We described an in silico multi-epitope vaccine targeting Bunyumwera virus nucleocapsid N-protein and predic...

    Authors: Kanaka Durga Devi Nelluri, Manne Anupama Ammulu, M. Lakshmi Durga, Melika Sravani, Vemuri Praveen Kumar and Sudhakar Poda
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:89
  20. In seek of potent and non-toxic iminoguanidine derivatives formerly assessed as active Pseudomonas aeruginosa inhibitors, a combined mathematical approach of quantitative structure-activity relationship (QSAR)...

    Authors: Emmanuel Israel Edache, Adamu Uzairu, Paul Andrew Mamza and Gideon Adamu Shallangwa
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:88
  21. Lignocellulosic biomasses produced from agriculture and forest-based industries are the cheapest or negative-cost biomass with a great potential for biotransformation to value-added bioproducts. Paper mill slu...

    Authors: Tuhin Das, Ferdausi Ali and Md. Shafiqur Rahman
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:87
  22. Aegilops tauschii Coss. as a donor of wheat D genome has an important role in wheat breeding programs. Genetic and phylogeographic diversity of 79 Ae. tauschii accessions collected from north and northwest of Ira...

    Authors: Sona Minaei, Seyyed Abolghasem Mohammadi, Atefeh Sabouri and Ahmad Reza Dadras
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:86
  23. This study was designed to generate functional insulin-producing cells (IPCs) from dental-derived mesenchymal stem cells (MSCs) and further explore their therapeutic potential against diabetes mellitus in vivo...

    Authors: Riham M. Aly, Hadeer A. Aglan, Ghada Nour Eldeen, Nadia S. Mahmoud, Eman H. Aboul-Ezz and Hanaa H. Ahmed
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:85
  24. Fibroblast growth factor 21 (FGF-21), alpha-amylase, and alpha-glucosidase are key proteins implicated in metabolic dysregulations. Bisphenol A (BPA) is an environmental toxicant known to cause endocrine dysre...

    Authors: P. M. Aja, J. N. Awoke, P. C. Agu, A. E. Adegboyega, E. M. Ezeh, I. O. Igwenyi, O. U. Orji, O. G. Ani, B. A. Ale and U. A. Ibiam
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:84
  25. Schizophrenia is a chronic mental disorder with different symptoms. The environmental and genetic factors are suggested to be the etiology of schizophrenia. However, the exact cause and pathogenesis of schizop...

    Authors: Maged Mostafa, Aya Ahmed Fathy, Mohamed Elwasify and Maha Abdelsalam
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:83
  26. Protease is one of the most important industrial enzymes. The importance of protease bioproduction comes from meeting the increasing demand for this enzyme especially in the cheese industry. Rhizomucor miehei pro...

    Authors: Houthail Alahmad Aljammas, Sabah Yazji and Abdulhakim Azizieh
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:82
  27. Antarctica is one of the harshest environments in the world. Despite this fact, it has been colonized by microorganisms, which had to develop different adaptations in order to survive. By studying their enzyme...

    Authors: P. Rios, B. Bezus, S. Cavalitto and I. Cavello
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:81
  28. Sugarcane hemicellulosic material is a compelling source of usually neglected xylose that could figure as feedstock to produce chemical building blocks of high economic value, such as xylitol. In this context, Sa...

    Authors: Fellipe da Silveira Bezerra de Mello, Carla Maneira, Frank Uriel Lizarazo Suarez, Sheila Nagamatsu, Beatriz Vargas, Carla Vieira, Thais Secches, Alessando L. V. Coradini, Maria Augusta de Carvalho Silvello, Rosana Goldbeck, Gonçalo Amarante Guimarães Pereira and Gleidson Silva Teixeira
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:80
  29. Successful rhizosphere colonization by plant growth promoting rhizobacteria (PGPR) is of crucial importance to perform the desired plant growth promoting activities. Since rhizocompetence is a dynamic process ...

    Authors: Donia S. Helal, Hussein El-khawas and Tarek R. Elsayed
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:79
  30. COVID-19 is an illness caused by severe acute respiratory syndrome coronavirus 2. Due to its rapid spread, in March 2020 the World Health Organization (WHO) declared pandemic. Since the outbreak of pandemic ma...

    Authors: Abas Sezer, Mervisa Halilović-Alihodžić, Annissa Rachel Vanwieren, Adna Smajkan, Amina Karić, Husein Djedović and Jasmin Šutković
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:78
  31. Newcastle disease virus (NDV) belongs to the genus Avaluvirus and Paramyxoviridae family, and it can cause acute, highly contagious Newcastle disease in poultry. The two proteins, haemagglutinin neuraminidase (HN...

    Authors: Mohammadreza Shafaati, Masoud Ghorbani, Minoo Mahmoodi, Mostafa Ebadi and Reza Jalalirad
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:77
  32. Many active peptides have been found in frog skin secretions. In this paper, our research focused on Pelophylax nigromaculatus and found a broad-spectrum antimicrobial peptide Nigrocin-PN based on the molecular c...

    Authors: Chengyu Lu, Lingling Liu, Chengbang Ma, Liuqing Di and Tianbao Chen
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:76
  33. Metabolic syndrome (MetS) is a combination of many health complications, such as obesity, high blood pressure, hyperlipidemia, hyperglycemia, and insulin resistance, with an increasing threat of type 2 diabete...

    Authors: Amira Mohamed Abd El-Jawad, Iman Hassan Ibrahim, Moushira Erfan Zaki, Tahany Ramzy Elias, Wafaa Ibrahim Rasheed and Khalda Said Amr
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:75
  34. Gongronella butleri is a fungus with many industrial applications including the composting of solid biowaste. Kerala Agricultural University, India, has developed a microbial consortium of which GbKAU strain of G...

    Authors: Ravisankar Valsalan, Deepu Mathew and Girija Devaki
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:74
  35. Among the most common causes of invasive aspergillosis and acute bronchopulmonary aspergillosis is Aspergillus fumigatus. Transmission with A. fumigatus produces aggressive aspergillosis in allogeneic haematopoie...

    Authors: Darakshan Jabin and Ajay Kumar
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:72
  36. In the past, simple sequence repeat (SSR) marker development in coconut is achieved through microsatellite probing in bacterial artificial chromosome (BAC) clones or using previously developed SSR markers from...

    Authors: Reina Esther S. Caro, Jesmar Cagayan, Roanne R. Gardoce, Anand Noel C. Manohar, Alma O. Canama-Salinas, Ramon L. Rivera, Darlon V. Lantican, Hayde F. Galvez and Consorcia E. Reaño
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:71
  37. Several SARS-CoV-2 variants with increased transmissibility and/or potential immune escape have emerged and rapidly spread worldwide. Ongoing surveillance analyses are performed worldwide to designate new vari...

    Authors: Ghada Ismail, Hossam Abdelghaffar, Mohamed G. Seadawy, Mostafa F. El-Hosseny, Ahmed F. Gad, Amr Ageez, Ahmed ElShafei, Shereen Saeed Mohammed, Marym Saied Ali and Marwa abd El-Rasoul El-Ashry
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:70
  38. Nonalcoholic fatty liver disease (NAFLD) showed significant association with PNPLA3 rs738409 polymorphism in unrelated individuals. However, it is still unknown whether the relationship of NAFLD with PNPLA3 varia...

    Authors: Muhammad Adnan, Abdul Wajid, Wasif Noor, Andleeb Batool, Muhammad Aasim, Kamran Abbas and Quratul Ain
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:68
  39. The green peach aphid, Myzus persicae Sulzer, and the bean aphid, Aphis fabae Scopoli (both Hemiptera: Aphididae), are serious pests of greenhouse vegetable crops in Iraq and other regions of the globe. In this s...

    Authors: Akram A. Mohammed, Firas A. Ahmed, Amal S. Younus, Ali A. Kareem and Ali M. Salman
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:67
  40. Tamoxifen resistance in estrogen receptor positive (ER+) breast cancer therapy increases, which is the leading cause of cancer treatment failure, as it can impair patients’ prognoses, cause cancer recurrence, ...

    Authors: Wilfan Ibadurrahman, Naufa Hanif and Adam Hermawan
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:66
  41. The global COVID-19 pandemic caused by SARS-CoV2 infected millions of people and resulted in more than 4 million deaths worldwide. Apart from vaccines and drugs, RNA silencing is a novel approach for treating ...

    Authors: Vijaya Sai Ayyagari
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:65
  42. Cancer is a group of diseases involving abnormal cell growth with the potential to invade or spread to other parts of the body. It is unlikely that there will ever be a single cure for cancer, but the developm...

    Authors: Lingling Liu, Xunan Wang, Yue Li, Chengyao Ma, Yeye Shi, Xiang Li and Jianwei Chen
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:64
  43. DNA barcoding is a powerful method for phylogenetic mapping and species identification. However, recent research has come to a consistent conclusion about the universality of DNA barcoding. We used matK and rbcL ...

    Authors: Ravi Prakash Srivastava, Gauri Saxena, Lav Singh, Arpit Singh, Praveen C. Verma and Gurminder Kaur
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:63
  44. During the last decade, enormous research efforts have been directed at identifying potent microorganisms as sustainable green cell factories for eco-friendly pigments. Talaromyces atroroseus has recently been sh...

    Authors: Rasha G. Salim, Mohamed Fadel, Yehya A. Youssef, Hanan A. A. Taie, Nivien A. Abosereh, Ghada M. El-Sayed and Mohamed Marzouk
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:62
  45. Salicornia is a halophyte plant capable of being irrigated with seawater, which can be used as an alternative food. Given this, it is necessary to study the potentials of this plant’s morphological diversity in ...

    Authors: Mohammad Aghaei, Abbas Hassani, Hosein Nazemiyeh, Babak Abdollahi Mandoulkani and Mohammad Saadatian
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:61
  46. The novel coronavirus (SARS-CoV-2) caused lethal infections worldwide during an unprecedented pandemic. Identification of the candidate viral epitopes is the first step in the design of vaccines against the vi...

    Authors: Nourelislam Awad, Rania Hassan Mohamed, Nehal I. Ghoneim, Ahmed O. Elmehrath and Nagwa El-Badri
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:60

    The Correction to this article has been published in Journal of Genetic Engineering and Biotechnology 2022 20:69

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