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Journal of Genetic Engineering and Biotechnology
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  1. Cellulose is the most prevalent biomass and renewable energy source in nature. The hydrolysis of cellulosic biomass to glucose units is essential for the economic exploitation of this natural resource. Cellula...

    Authors: Zainab E. Elsababty, Samir H. Abdel-Aziz, Atef M. Ibrahim, Adel A. Guirgis and Ghada E. Dawwam
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:34
    Content type: Research Published on:

  2. Cerium-containing materials have wide applications in the biomedical field, because of the mimetic catalytic activities of cerium. The study aims to deeply estimate the biocompatibility of different scaffolds ...

    Authors: Hanan F. Hammouda, Mohammad M. Farag, Mervat M. F. El Deftar, M. Abdel-Gabbar and Basant M. Mohamed
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:33
    Content type: Research Published on:

  3. The increased demand for oil and fats to satisfy the ever-increasing human needs has enhanced the research in this field. Single-cell oils or microbial lipids produced by oleaginous microorganisms are being ut...

    Authors: Mohamed E. Osman, Asharf Bakery Abdel-Razik, Khaled I. Zaki, Nesma Mamdouh and Heba El-Sayed
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:32
    Content type: Research Published on:

  4. The B30.2 variants lead to most relevant severity forms of familial Mediterranean fever (FMF) manifestations. The B30.2 domain plays a key role in protein-protein interaction (PPI) of pyrin with other apoptosi...

    Authors: Alaaeldin G. Fayez, Ghada Nour Eldeen, Waheba A. Zarouk, Khaled Hamed, Abeer Ramadan, Bardees M. Foda, Maha M. Kobesiy, Mai E. Zekrie, Randa S. Lotfy, Mona F. Sokkar and Hala T. El-Bassyouni
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:31
    Content type: Research Published on:

  5. The role of atrial natriuretic peptide (ANP) in edema formation in idiopathic nephrotic syndrome (INS) was studied before with conflicting results reported; however, the possible contribution of genes regulati...

    Authors: Hanan El-Halaby, Ashraf Bakr, Riham Eid, Hussein Abdelaziz Abdalla, Nashwa Hamdy, Nora Shamekh, Amira Adel and Ahmed El-Husseiny
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:30
    Content type: Research Published on:

  6. Durian (Durio zibethinus L.) is a tropical fruit crop which is popular in Southeast Asia but recently gaining popularity in other parts of the world. In this study, we analyzed the resistance gene analogs (RGAs) ...

    Authors: Cris Q. Cortaga, Romnick A. Latina, Rosteo R. Habunal and Darlon V. Lantican
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:29
    Content type: Short Communications Published on:

  7. Plant grows in nature facing various types of abiotic stresses for their normal growth and development. During abiotic stress, plants evolve different types of mechanisms to survive in a hostile environment. P...

    Authors: Md. Abu Sadat, Md. Wali Ullah, Md. Sabbir Hossain, Borhan Ahmed and Kazi Khayrul Bashar
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:28
    Content type: Research Published on:

  9. Lactic acid bacteria (LAB) could be used for bio-production of lactic acid (LA) from wastes of dairy industries. This study aimed to produce LA using isolated and identified LAB capable of withstanding high sa...

    Authors: Atiat Sayed Dosuky, Tarek Ragab Elsayed, Eman Tawfik Yousef, Olfat Sayed Barakat and Nasr Fawzy Nasr
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:26
    Content type: Research Published on:

  10. The Plant U-box (PUB), ubiquitin ligase gene, has a highly conserved domain in potato. However, little information is available about U-box genes in potato (Solanum tuberosum). In this study, 62 U-box genes were ...

    Authors: Zahra Hajibarat, Abbas Saidi, Mehrshad Zeinalabedini, Ahmad Mosuapour Gorji, Mohammad Reza Ghaffari, Vahid Shariati and Rahim Ahmadvand
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:25
    Content type: Research Published on:

  11. The present study focuses on the isolation of Bacillus thuringiensis bacterium from the gut of fresh water fish, Systomus sarana, the innovative optimization of culture parameters to produce maximum protease enzy...

    Authors: Arul Dhayalan, Balasubramanian Velramar, Balasubramani Govindasamy, Karthik Raja Ramalingam, Aiswarya Dilipkumar and Perumal Pachiappan
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:24
    Content type: Research Published on:

  12. Amylase is used commercially in food, textiles, sugar syrup, paper, and detergent industries. Bacteria and fungi remain a significant source of industrial enzymes. Pleurotus tuberregium is a macro-fungi that can ...

    Authors: Comfort Olukemi Bamigboye, Raphael E. Okonji, Iyanu Oluwalonimi Oluremi and Victoria James
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:23
    Content type: Research Published on:

  13. This study targets the enhanced production of l-asparaginase, an antitumor enzyme by Acinetobacter baumannii ZAS1. This organism is an endophyte isolated from the medicinal plant Annona muricata. Plackett–Burman ...

    Authors: K. N. Abhini, Akhila B. Rajan, K. Fathimathu Zuhara and Denoj Sebastian
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:22
    Content type: Research Published on:

  14. Oxidative stress is among the most common risk factors in the pathogenesis of acute myocardial infarction (AMI). Glutathione peroxidase 1 enzyme coded by the GPX1 gene plays an essential role in reducing oxidativ...

    Authors: Lamia K. Ismail, Mohamed F. Abdel Rahman, Ingy M. Hashad and Sahar M. Abdel-Maksoud
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:21
    Content type: Research Published on:

  15. Wadi El Natrun microorganisms have been considered as a new resource for natural products due to its extreme condition of salinity and alkalinity. Therefore, this study was devoted to generate metagemic librar...

    Authors: Safaa M. Ali, Nadia A. Soliman, Samia Abd Allah Abdal-Aziz and Yasser R. Abdel-Fattah
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:20
    Content type: Research Published on:

  16. A major discovery in human etiology recognized that cervical cancer is a consequence of an infection caused by some mucosatropic types of human papillomavirus (HPV). Since L1 protein of HPV is able to induce t...

    Authors: Apon Zaenal Mustopa, Lita Meilina, Shasmita Irawan, Nurlaili Ekawati, Alfi Taufik Fathurahman, Lita Triratna, Arizah Kusumawati, Anika Prastyowati, Maritsa Nurfatwa, Ai Hertati and Rikno Harmoko
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:19
    Content type: Research Published on:

  17. The primary amino acid sequence of a protein is a translated version from its gene sequence which carries important messages and information concealed therein. The present study unveils the structure-function ...

    Authors: Krishnendu Pramanik and Narayan Chandra Mandal
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:18
    Content type: Research Published on:

  18. Diabetic retinopathy (DR) is a common microvascular complication of diabetes. There is strong evidence suggesting that DR has an inheritable component. The interaction between advanced glycation end products (...

    Authors: Pragya Ahuja, Abdul Waris, Sheelu Shafiq Siddiqui and Amit Mukherjee
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:17
    Content type: Review Published on:

  19. Castor bean (Ricinus communis L.) is an important cultivated oilseed. Seeds contain ricinoleic acid, a valuable product for a variety of industries. Castor cake is a residue of ricinoleic manufacture and could be...

    Authors: Natália L. de Sousa, Glaucia B. Cabral and Francisco J. L. Aragão
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:16
    Content type: Short Communications Published on:

  20. Mitochondrial complex ΙΙ has a unique biological role owing to its participation in both the citric acid cycle and the electron transport chain. Our goal was to evaluate the succinate dehydrogenase and ubiquin...

    Authors: Eman M. Ragab, Doaa M. El Gamal, Tarek M. Mohamed and Abeer A. Khamis
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:15
    Content type: Research Published on:

  21. The marine environment hosts a wide variety of species that have evolved to live in harsh and challenging conditions. Marine organisms are the focus of interest due to their capacity to produce biotechnologica...

    Authors: Akash Karthikeyan, Abey Joseph and Baiju G. Nair
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:14
    Content type: Review Published on:

  22. Association between Helicobacter pylori (H. pylori) and chronic hepatitis C (CHC) still remains controversial. This work is concerned with assessing the potential role of H. pylori in the progression of hepatitis...

    Authors: Abdelfattah M. Attallah, Mohamed S. Albannan, Mohamed F. Ghaly, Sally E. Sallam, Mahmoud M. Amer and Attia A. Attia
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:13
    Content type: Research Published on:

  23. Although microbial fuel cells (MFCs) represent a promising technology for capturing renewable energy from wastewater, their scaling-up is significantly limited by a slow-rate cathodic oxygen reduction reaction...

    Authors: Dena Z. Khater, R. S. Amin, M. O. Zhran, Zeinab K. Abd El-Aziz, Mohamed Mahmoud, Helmy M. Hassan and K. M. El-Khatib
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:12
    Content type: Research Published on:

  24. Essential hypertension (EH) is an important risk factor for various cardiovascular, cerebral and renal disorders. It is a multi-factorial trait which occurs through complex interplay between genetic, epigeneti...

    Authors: Mayank Chaudhary
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:11
    Content type: Review Published on:

  26. Phytochromes are the best characterized photoreceptors that perceive Red (R)/Far-Red (FR) signals and mediate key developmental responses in plants. It is well established that photoperiodic control of floweri...

    Authors: Stuti Krishna, Kaushal Modha, Vipulkumar Parekh, Ritesh Patel and Digvijay Chauhan
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:9
    Content type: Research Published on:

  27. Myelin basic protein (MBP) is one of the most important structural components of the myelin sheaths in both central and peripheral nervous systems. MBP has several functions including organization of the myeli...

    Authors: Juan Sebastian Cruz-Méndez, María Paula Herrera-Sánchez, Ángel Enrique Céspedes-Rubio and Iang Schroniltgen Rondón-Barragán
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:8
    Content type: Research Published on:

  28. Tumor necrosis factor alpha (TNFA) is an important cytokine that influences multiple biological processes. It is one of the key mediators of acute and chronic systemic inflammatory reactions and plays a centra...

    Authors: Tamim Ahsan and Abu Ashfaqur Sajib
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:7
    Content type: Research Published on:

  29. An amendment to this paper has been published and can be accessed via the original article.

    Authors: K. H. T. Karunarathna, N. H. K. S. Senathilake, K. M. Mewan, O. V. D. S. J. Weerasena and S. A. C. N. Perera
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:6
    Content type: Correction Published on:

    The original article was published in Journal of Genetic Engineering and Biotechnology 2020 18:32

  30. Silver nanoparticles (AgNPs) are the most widely used nanomaterial in agricultural and environmental applications. In this study, the impact of AgNPs solutions at 20 mg/L, 40 mg/L, 80 mg/L, and 160 mg/L on cel...

    Authors: May Labeeb, Abdelfattah Badr, Soliman A. Haroun, Magdy Z. Mattar and Aziza S. El-kholy
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:5
    Content type: Research Published on:

  31. Hepatocellular carcinoma (HCC) is considered one of the most common cancers related to mortality around the world, and susceptibility is related with genetic, lifestyle, and environmental factors. Copy number ...

    Authors: Eman Abd El Razek Abbas, Ahmed Barakat Barakat, Mohamed Hassany and Samar Samir Youssef
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:4
    Content type: Research Published on:

  32. Guava fruit softening is a crucial process during ripening and this process involves a number of enzymes that modifies the cell wall. Two of the enzymes that regulate this process are (a) the β-1, 4-endoglucan...

    Authors: Mario A. Mejía-Mendoza, Cristina Garcidueñas-Piña, José S. Padilla-Ramírez, Ruth E. Soria-Guerra and José Francisco Morales-Domínguez
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:3
    Content type: Research Published on:

  33. Lignin is a complex polymer of phenyl propanoid units found in the vascular tissues of the plants as one of lignocellulose materials. Many bacteria secrete enzymes to lyse lignin, which can be essential to eas...

    Authors: Subhashree Rath, Manish Paul, Hemanta Kumar Behera and Hrudayanath Thatoi
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:2
    Content type: Research Published on:

  34. In the present study, adaptive laboratory evolution was used to stimulate antibiotic production in a Streptomyces strain JB140 (wild-type) exhibiting very little antimicrobial activity against bacterial pathogens...

    Authors: Dharmesh Harwani, Jyotsna Begani, Sweta Barupal and Jyoti Lakhani
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:1
    Content type: Research Published on:

  35. Autoinflammatory disorders are the group of inherited inflammatory disorders caused due to the genetic defect in the genes that regulates innate immune systems. These have been clinically characterized based o...

    Authors: Abhinav Jain, Rahul C. Bhoyar, Kavita Pandhare, Anushree Mishra, Disha Sharma, Mohamed Imran, Vigneshwar Senthivel, Mohit Kumar Divakar, Mercy Rophina, Bani Jolly, Arushi Batra, Sumit Sharma, Sanjay Siwach, Arun G. Jadhao, Nikhil V. Palande, Ganga Nath Jha…
    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:183
    Content type: Research Published on:

  36. Many species of mushroom contain an assortment of free radical scavengers (Phenolics and Flavonoids compounds) that have made them nutritionally beneficial and a source of expansion of drug production. In this...

    Authors: Amal I. Hassan, Mona A. M. Ghoneim, Manal G. Mahmoud and Mohsen S. Asker
    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:182
    Content type: Research Published on:

  37. The Pehuén or Monkey puzzle tree (Araucaria araucana) is an evergreen coniferous tree, which has been historically used for social, medicinal, and nutritional purposes. We have recently showed the value of A. ara...

    Authors: María C. Gallia, Julieta Echeverri Del Sarto and Guillermina A. Bongiovanni
    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:181
    Content type: Research Published on:

  38. Despite a reduction in global HIV prevalence the development of a pipeline of new therapeutics or pre-exposure prophylaxis to control the HIV/AIDS epidemic are of high priority. Antibody-based therapies offer ...

    Authors: Advaita Acarya Singh, Priyen Pillay, Lusisizwe Kwezi and Tsepo Lebiletsa Tsekoa
    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:180
    Content type: Short Communications Published on:

  39. Various bacteria promote plant root growth in the rhizosphere, as a measure of securing and enlarging their ecological niche. These interactions are mediated by plant growth regulators (PGRs) such as auxin, an...

    Authors: Seunghye Park, A-Leum Kim, Yoon-Kyung Hong, Ji-Hwan Shin and Se-Hwan Joo
    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:179
    Content type: Research Published on:

  40. Finger millet is the most important food grain in the world for its nutritional benefits. Finger millet is genetically and geographically diverse and widely spread in the African and Asian sub-continent. There...

    Authors: Jayalakshmi Venkatesan, Vasuki Ramu, Thilaga Sethuraman, Chandrasekaran Sivagnanam and Ganesh Doss
    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:178
    Content type: Research Published on:

  41. Leaf senescence occurs in an age-dependent manner, but the rate and timing of leaf senescence may be influenced by various biotic and abiotic factors. In the course of stress, the function, composition, and di...

    Authors: Shamsu Ado Zakari, Syed Hassan Raza Zaidi, Mustapha Sunusi and Kabiru Dawaki Dauda
    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:177
    Content type: Research Published on:

  42. Polycystic ovary syndrome (PCOS) is a chronic endocrine disorder prevalent in premenopausal women and is characterized by a range of physiological and biochemical abnormalities which may include reproductive, ...

    Authors: Fehintoluwa Joy Femi-Olabisi, Ahmed Adebayo Ishola, Opeyemi Faokunla, Anthonia Oluyemi Agboola and Benjamin Ayodipupo Babalola
    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:176
    Content type: Research Published on:

  43. Gerbera jamesonii Bolus ex Hooker f. (African daisy) is listed among the top five most important ornamental plants in the global floricultural industry. To satisfy its demand, the floriculture industry relies on...

    Authors: Saikat Gantait and Manisha Mahanta
    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:175
    Content type: Research Published on:

  44. Orthotropic liver transplantation (OLT) offers a therapeutic choice for hepatocellular carcinoma (HCC) patients. The poor outcome of liver transplantation is HCV recurrence. Several genome-wide associated stud...

    Authors: Ghada M. Salum, Mai Abd el Meguid, Tawfeek H. Abelhafez, Eman Medhat, Ashraf O. Abdel Aziz and Reham Dawood
    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:174
    Content type: Research Published on:

  45. The era of first green revolution brought about by the application of chemical fertilizers surely led to the explosion of food grains, but left behind the notable problem of salinity. Continuous application of...

    Authors: Mandeep Singh, Usha Nara, Antul Kumar, Anuj Choudhary, Hardeep Singh and Sittal Thapa
    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:173
    Content type: Review Published on:

  46. Since the index case was reported in China, COVID-19 has led to the death of at least 4 million people globally. Although there are some vaccine cocktails in circulation, the emergence of more virulent variant...

    Authors: Tolulope Peter Saliu, Haruna I. Umar, Olawale Johnson Ogunsile, Micheal O. Okpara, Noriyuki Yanaka and Olusola Olalekan Elekofehinti
    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:172
    Content type: Research Published on:

  47. Biotechnological breeding of elite sugarcane cultivars is currently limited because of the difficulty of regenerating plants by tissue culture. Here, we report that commercially elite sugarcane genotypes, whic...

    Authors: Valentina Di Pauli, Paola Daniela Fontana, Dalia Marcela Lewi, Arturo Felipe and Luis Ernesto Erazzú
    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:171
    Content type: Research Published on:

  48. Insulin-like growth factor 2 (IGF2) is one of three hormones that share high structural similarity to insulin. It is involved in several insulin-like growth-regulating and mitogenic activities. This study was con...

    Authors: Dhafer A. Ali, Mohammed Baqur S. Al-Shuhaib, Golzar Farhadi, Fadhil R. Al-Kafajy, Tahreer M. Al-Thuwaini and Ali Esmailizadeh
    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:170
    Content type: Research Published on:

  49. Genetic variants in the transcription factor 7-like 2 (TCF7L2) gene are related with type 2 diabetes (T2D) and gestational diabetes mellitus (GDM) in various populations, but there are not enough statistics regar...

    Authors: Taghreed A. Shalabi, Khalda S. Amr and Mai M. Shaker
    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:169
    Content type: Research Published on:

  50. The coexistence of cirrhosis complicates the early detection of hepatocellular carcinoma (HCC). Thus, novel biomarkers for HCC early detection are needed urgently. Traditionally, HCC detection is carried out b...

    Authors: Mohamed M. Omran, Sara Mosaad, Tarek M. Emran, Fathy M. Eltaweel and Khaled Farid
    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:168
    Content type: Research Published on:
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  • ISSN: 2090-5920 (electronic)