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  1. There is always a need for a safe and efficient vaccine platform, especially when facing a pandemic such as COVID-19. Most of the SARS-CoV-2-based vaccines are based on the full spike protein, which is present...

    Authors: Mohamed A. Wahba, Dina Mofed, Doaa A. Ghareeb, Jihad I. Omran and Tamer Z. Salem
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:16
  2. Flavonoid natural dyes have gained attention because they are nontoxic and eco-friendly. However, they do not work effectively with artificial fibers and require the use of mordants, which are considered as ha...

    Authors: Yasmin M. Elsaba, Heba M. El-Hennawi, Mona M. Ibrahim and Hala R. Wehaidy
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:14
  3. Carbohydrates are known as the main natural products of life activities.

    Authors: Sahar Saleh Mohamed, Mohamed E. El Awady, Sayeda Abdelrazek Abdelhamid, Ahmed Abdelghani Hamed, Abeer A. A. Salama and Manal S. Selim
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:12
  4. Mating elicits significant changes in gene expression and leads to subsequent physiological and behavioural modifications in insects. The reproductive success of both sexes is contributed immensely by the male...

    Authors: R. Mamtha, Tannavi Kiran, Vivek Chandramohan, B. S. Gowrishankar and D. Manjulakumari
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:11
  5. In today’s society, cancer has become a big concern. The most common cancers in women are breast cancer (BC), endometrial cancer (EC), ovarian cancer (OC), and cervical cancer (CC). CC is a type of cervix canc...

    Authors: Md. Tanvir Hasan, Md. Rakibul Islam, Md. Rezwan Islam, Baraa Riyadh Altahan, Kawsar Ahmed, Francis M. Bui, Sami Azam and Mohammad Ali Moni
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:10
  6. Cisplatin resistance is one of the major contributors to the poor survival rate among head and neck cancer (HNC) patients. Focusing on the protein–protein interaction rather than a single protein could provide...

    Authors: Raushan Kumar Chaudhary, Pukar Khanal, Uday Venkat Mateti, C. S. Shastry and Jayarama Shetty
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:9
  7. Cadmium is a non-essential, third largest heavy metal contaminant with long retention time that poses environmental hazards. It emanating majorly from industrial processes and phosphate fertilizers. Cadmium is...

    Authors: Chinreddy Subramanyam Reddy, Min Cho, Tanushri Kaul, Jin Tae Joeng and Kang Min Kim
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:8
  8. Thrombin is the most important enzyme in the hemostatic process by permitting rapid and localized coagulation in case of tissue damage. Camel thrombin is the natural and proper target enzyme for the previously...

    Authors: Mahmoud A. Ibrahim and Hassan M. M. Masoud
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:7
  9. Rg3-ginsenoside, a protopanaxadiol saponin, is a well-known adaptogen used for the prevention of cancer and inflammation. However, despite its distinct biological activity, the concentration of Rg3 in the tota...

    Authors: Zuneera Marium, Muhammad Zubair Siddiqi, Ji-Hye Lee, Wan-Taek Im and Seong-Gu Hwang
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:6
  10. Sucrose non-fermenting-1 (SNF1)-related protein kinase 2 (SnRK2), a plant-specific serine/threonine kinase family, is associated with metabolic responses, including abscisic acid signaling under biotic and abi...

    Authors: Borhan Ahmed, Fakhrul Hasan, Anika Tabassum, Rasel Ahmed, Rajnee Hassan, Md. Ruhul Amin and Mobashwer Alam
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:5
  11. Ziziphus species particularly Ziziphus mauritiana and Ziziphus nummularia constitute an important part of genetic resources in India. They contribute economically as a fruit crop with lots of morphological and po...

    Authors: Amit Sareen, Vikas Sharma and Raghbir Chand Gupta
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:4
  12. CRISPR/Cas9 is the most powerful and versatile genome-editing tool that permits multiplexed-targeted gene modifications for the genetic enhancement of oil palm. Multiplex genome-editing has recently been devel...

    Authors: Bohari Bahariah, Mat Yunus Abdul Masani, Md Piji Mohd Al Akmarul Fizree, Omar Abd Rasid and Ghulam Kadir Ahmad Parveez
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:3
  13. Angina pectoris (AP) occurs when oxygen and other nutrients are insufficient to meet the metabolic needs of the heart muscle. Stable angina is the most common, while the unstable angina is less frequent. Tumor...

    Authors: Shaimaa Y. Abdulfattah and Farah Thamer Samawi
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:2
  14. Cynopterus brachyotis (Müller 1838) is a generalist and widespread fruit bat species which inhabits different types of habitats in Southeast Asia. This species plays an essential role as a seed disperser and poll...

    Authors: Husni Mubarok, Niken Satuti Nur Handayani, Ibnu Maryanto and Tuty Arisuryanti
    Citation: Journal of Genetic Engineering and Biotechnology 2023 21:1
  15. Low-temperature expression of recombinant proteins may be advantageous to support their proper folding and preserve bioactivity. The generation of expression vectors regulated under cold conditions can improve...

    Authors: Yaneth Bartolo-Aguilar, Cipriano Chávez-Cabrera, Luis Bernardo Flores-Cotera, Jesús Agustín Badillo-Corona, Carmen Oliver-Salvador and Rodolfo Marsch
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:173
  16. The spread of HIV is on the rise and has become a global issue, especially for underdeveloped and developing countries. This is due to the fact that HIV majorly occurs asymptomatically and is implausible for e...

    Authors: Jyotsna Jai, Deborah Shirleen, Christian Hanbali, Pamela Wijaya, Theresia Brigita Anginan, William Husada and Muhammad Yogi Pratama
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:172
  17. Endophytes are a rich source of novel, distinct, and applicable compounds of interest in agricultural, medical, cosmetic, and pharmaceutical industries. In this respect, they have been attracting growing inter...

    Authors: Siphiwe G. Mahlangu and Siew L. Tai
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:171
  18. Mondia whitei root is often used in Africa as a local therapeutic agent for libido enhancement. The fractions of the M. whitei leaves (MWL) lack chemical characterization of their bioactive components and possibl...

    Authors: Hope Onohuean, Fanny Eseohe Onohuean, Sharon Iyobor Igbinoba, Joseph Obiezu Chukwujekwu Ezeonwumelu, Peter Chinedu Agu, Josiah Eseoghene Ifie, Tusubira Deusdedit and Patrick Maduabuchi Aja
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:170
  19. Arylacetamide deacetylase (AADAC) is a lipolytic enzyme involved in xenobiotic metabolism. The characterization in terms of activity and substrate preference has been limited to a few mammalian species. The po...

    Authors: Tania Diaz-Vidal, Christian Berenice Romero-Olivas and Raúl Balam Martínez-Pérez
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:169
  20. Natural dyes are present in living organisms such as animals and plants and microorganisms such as fungi, bacteria, algae, and yeast. Pigments are fast and easy growth by using cheap components and do not effe...

    Authors: Nesma A. Hemeda, Ghada E. Hegazy, Soad A. Abdelgalil, Nadia A. Soliman, Dina I. Abdel-Meguid and Samy A. El-Assar
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:168
  21. Several species in Lactobacillaceae family were recognized as potential probiotic bacteria. In this group of lactic acid bacteria, species are taxonomically closed and usually share similar 16S rRNA gene, thus, i...

    Authors: Nora Laref and Khadidja Belkheir
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:167
  22. A useful technique for growing large amounts of plant material is in vitro propagation of important medicinal plants. The present investigation deals with the enhancement of secondary metabolite production via...

    Authors: Asmaa M. Khalifa, Eman Abd-ElShafy, Rasha Abu-Khudir and Reda M. Gaafar
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:166
  23. Mass propagation of date palm has attracted the interest of commercial producers. However, this technique still faces many obstacles that hinder production. This study investigated the effect of chitosan (CHT)...

    Authors: Ahmed Madi Waheed Al-Mayahi
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:165
  24. Homocystinuria is an inherited, inborn error of homocysteine metabolism, which leads to the abnormal accumulation of homocysteine and its metabolites in blood and urine, resulting in various complications. Var...

    Authors: Nadeesha Samarasinghe, Dinithi Mahaliyanage, Sumadee De Silva, Eresha Jasinge, Nimal Punyasiri and H. W. Dilanthi
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:164
  25. Ryegrass is a promising crop for the development of meadow farming in the world. More than 1000 cultivated varieties widely used in feed production have been developed, based on the main species — perennial ry...

    Authors: Yulian Mavlyutov, Sergey Kostenko, Anastasia Shamustakimova and Irina Klimenko
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:163
  26. The Himalayas have always been an enigma and, being biodiversity hotspots, are considered extremely important from an ecological point of view. Recent advances in studies regarding high-altitude lakes have gar...

    Authors: Aditi Rai, Shyama Prasad Saha, Toral Manvar and Arindam Bhattacharjee
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:162
  27. Monocyte-macrophage lineage cells are committed towards osteoclast differentiation in vitro by the downregulation of microphthalmia-induced transcription factor (MITF) by miRNA-155. Therefore, we aimed to eval...

    Authors: Sowmya Reddy Nandipati, Devapriya Appukuttan, Sangeetha Subramanian and P. S. G. Prakash
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:161
  28. Mycoplasma gallisepticum is the primary agent of chronic respiratory disease in chickens creating important economic losses in poultry industry. pMGA and pvpA genes encode major surface proteins in M. galliseptic...

    Authors: Farzaneh pourkarimi Fatideh, Majid Esmaelizad, Mohammad Kargar, Majid Tebianian and Farshid Kafilzadeh
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:160
  29. Pyrazines are used in food industry to impart the foods nutty-roasted flavor. However, their extraction from natural sources is difficult and expensive. At the same time, there is awareness against the chemica...

    Authors: Hoda Hanem Mohamed Fadel, Mohsen Mohamed Selim Asker, Manal Gomaa Mahmoud, Shimaa Ragab Hamed and Shereen Nazeh Lotfy
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:159
  30. Acyrthosiphon pisum or pea aphid is an insect of the Aphididae family, which attacks various species of legumes such as beans and peas. This pest causes economically heavy crop losses around the world. The use of...

    Authors: Ouided Benslama
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:158
  31. Single-domain antibodies or nanobodies have recently attracted much attention in research and applications because of their great potential and advantage over conventional antibodies. However, isolation of can...

    Authors: Tuom Thi Tinh Truong, Viet Quoc Huynh, Nam Tri Vo and Hoang Duc Nguyen
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:157
  32. Cholesterol oxidases (CHOs) have attracted enormous attention because of their wide biotechnological potential. The present study explores the production of CHOs by Streptomyces sp. AN. Evaluation of culture cond...

    Authors: Amany A. Alam, Doaa A. Goda, Nadia A. Soliman, Dina I. Abdel-Meguid, Ebaa E. El-Sharouny and Soraya A. Sabry
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:156
  33. Recent studies and reports have documented the ability of the co-circulating seasonal influenza A/H1N1 (ancestor: 2009 pandemic H1N1) and A/H3N2 to exchange their genetic segments, generating a novel H1N2 stra...

    Authors: Mina Nabil Kamel, Sara H. Mahmoud, Yassmin Moatasim, Ahmed El Taweel, Mahmoud Shehata, Mohamed Refaat Shehata, Elsayed Tarek AbdElSalam, Mohamed A. Ali and Ahmed Mostafa
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:155
  34. Molecular genetics has been extremely useful in determining the relation between animal populations and documenting the degrees of genetic variation found within them. The present study was undertaken to evalu...

    Authors: Sekena H. Abdel-Aziem, Dalia M. Mabrouk, Heba A. Abd El-Kader, Sally S. Alam and Othman E. Othman
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:154
  35. This research work included bioinformatics modeling of the dipotassium-trioxohydroxytetrafluorotriborate-halogenated boroxine molecule, as well as simulation and prediction of structural interactions between t...

    Authors: Tarik Corbo, Abdurahim Kalajdzic, Dzelila Delic, Sumaia Suleiman and Naris Pojskic
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:153
  36. Andrographis producta (C. B. Clarke) Gamble is a valuable medicinal plant that yields several therapeutic compounds. In addition, this species is endemic to the Western Ghats regions of South India. Natural popul...

    Authors: Sathish Shekhappa Kadapatti and Hosakatte Niranjana Murthy
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:152
  37. Exopolysaccharides (EPSs) from microorganisms are essential harmless natural biopolymers used in applications including medications, nutraceuticals and functional foods, cosmetics, and insecticides. Several mi...

    Authors: Hassan A. H. Ibrahim, Hala E. Abou Elhassayeb and Waleed M. M. El-Sayed
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:151
  38. Morocco is considered one of the main biodiversity hotspots in the Mediterranean region and contains various plant species including wild and domestic Rosa. This genus is the most important among cultivated or...

    Authors: Karim Saghir, Rabha Abdelwahd, Driss Iraqi, Nezha Lebkiri, Fatima Gaboun, Younes El Goumi, Maha Ibrahimi, Younes Abbas and Ghizlane Diria
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:150
  39. COVID-19 is a disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Rigorous detection and treatment strategies against SARS-CoV-2 have become very challenging due to continuous evolu...

    Authors: Afzal Sheikh, He Huang, Sultana Parvin, Mohammad Badruzzaman, Tofayel Ahamed, Ekhtear Hossain, Iri Sato Baran and Zahangir Alam Saud
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:149
  40. Kidney disease (KD) is a public health problem worldwide and is an important factor in peripheral vascular disease, arrhythmias, heart failure, acute myocardial infarction, stroke, and angina. Obesity has been...

    Authors: Ahmed M. Darwish, Dalia M. Mabrouk, Hassan M. Desouky and Abd El-Nasser Khattab
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:148
  41. Methotrexate (MX), a competitive inhibitor of dihydrofolate reductase, can inhibit DNA and RNA production and is a powerful anticancer agent widely utilized in clinical practice for treating nonneoplastic mala...

    Authors: Mai O. Kadry, Naglaa M. Ammar, Heba A. Hassan and Rehab M. Abdel Megeed
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:147
  42. Chlamydia trachomatis is an obligate intracellular gram-negative pathogen, responsible for diverse affections, mainly trachoma and sexually transmitted diseases. Antibiotics are the commonly used drugs to tackle ...

    Authors: Ichrak Benamri, Maryame Azzouzi, Ahmed Moussa and Fouzia Radouani
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:146
  43. Artocarpus heterophyllus is an important tropical agroforestry species that bears multiple applications. However, the population of this species is reduced due to various anthropogenic activities. For this reaso...

    Authors: Abdul Kader, Sankar Narayan Sinha and Parthadeb Ghosh
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:145
  44. The toxicity profile of lactobacilli may be strain dependent, so it should be considered for safe utilization of probiotics. Further, in vivo studies are necessary to evaluate their safety.

    Authors: Mostafa G. Fadl and Zenat Kamel
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:144
  45. Skeletal muscle mishaps are the most well-known incidents in society, especially among athletes and the military population. From the various urgency, this accident needs to be cured more quickly. However, the...

    Authors: Muhamad Azhar, Bantari Wisynu Kusuma Wardhani and Editha Renesteen
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:143
  46. Acetaminophen (APAP) overdose is a common cause of hepatotoxicity. Antioxidants like N-acetyl cysteine are recommended as a therapeutic option; nevertheless, it has limitations. The search for efficient altern...

    Authors: Hend M. Ahmed, Hanan H. Shehata, Gamila S. M. El-Saeed, Hoda H. Abou Gabal and Sherien M. El-Daly
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:142
  47. Recombinant therapeutic anti-CD20 monoclonal antibody (mAb) is used for the treatment of non-Hodgkin’s lymphoma, a common B cell lymphoma constituting 80% of all lymphomas. Anti-CD20 mAb contains an Fc-linked ...

    Authors: Bala Reddy Bheemareddy, Prakash Narayana Reddy, Kranthi Vemparala and Vijaya R. Dirisala
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:141
  48. Candida tropicalis causes tropical invasive fungal infections, with a high mortality. This fungus has been found to be resistant to antifungal classes such as azoles, echinocandins, and polyenes in several studie...

    Authors: Nahid Akhtar, Arshwinder Singh, Atul Kumar Upadhyay and M. Amin-ul Mannan
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:140
  49. Authors: Mahideen Afridi, Khurshid Ahmad, Shahana Seher Malik, Nazia Rehman, Muhammad Yasin, Shujaul Mulk Khan, Adil Hussain and Muhammad Ramzan Khan
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:139

    The original article was published in Journal of Genetic Engineering and Biotechnology 2022 20:124

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