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Journal of Genetic Engineering and Biotechnology
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  1. Phytochromes are the best characterized photoreceptors that perceive Red (R)/Far-Red (FR) signals and mediate key developmental responses in plants. It is well established that photoperiodic control of floweri...

    Authors: Stuti Krishna, Kaushal Modha, Vipulkumar Parekh, Ritesh Patel and Digvijay Chauhan
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:9
    Content type: Research Published on:

  2. Myelin basic protein (MBP) is one of the most important structural components of the myelin sheaths in both central and peripheral nervous systems. MBP has several functions including organization of the myeli...

    Authors: Juan Sebastian Cruz-Méndez, María Paula Herrera-Sánchez, Ángel Enrique Céspedes-Rubio and Iang Schroniltgen Rondón-Barragán
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:8
    Content type: Research Published on:

  3. Tumor necrosis factor alpha (TNFA) is an important cytokine that influences multiple biological processes. It is one of the key mediators of acute and chronic systemic inflammatory reactions and plays a centra...

    Authors: Tamim Ahsan and Abu Ashfaqur Sajib
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:7
    Content type: Research Published on:

  4. An amendment to this paper has been published and can be accessed via the original article.

    Authors: K. H. T. Karunarathna, N. H. K. S. Senathilake, K. M. Mewan, O. V. D. S. J. Weerasena and S. A. C. N. Perera
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:6
    Content type: Correction Published on:

    The original article was published in Journal of Genetic Engineering and Biotechnology 2020 18:32

  5. Silver nanoparticles (AgNPs) are the most widely used nanomaterial in agricultural and environmental applications. In this study, the impact of AgNPs solutions at 20 mg/L, 40 mg/L, 80 mg/L, and 160 mg/L on cel...

    Authors: May Labeeb, Abdelfattah Badr, Soliman A. Haroun, Magdy Z. Mattar and Aziza S. El-kholy
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:5
    Content type: Research Published on:

  6. Hepatocellular carcinoma (HCC) is considered one of the most common cancers related to mortality around the world, and susceptibility is related with genetic, lifestyle, and environmental factors. Copy number ...

    Authors: Eman Abd El Razek Abbas, Ahmed Barakat Barakat, Mohamed Hassany and Samar Samir Youssef
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:4
    Content type: Research Published on:

  7. Guava fruit softening is a crucial process during ripening and this process involves a number of enzymes that modifies the cell wall. Two of the enzymes that regulate this process are (a) the β-1, 4-endoglucan...

    Authors: Mario A. Mejía-Mendoza, Cristina Garcidueñas-Piña, José S. Padilla-Ramírez, Ruth E. Soria-Guerra and José Francisco Morales-Domínguez
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:3
    Content type: Research Published on:

  8. Lignin is a complex polymer of phenyl propanoid units found in the vascular tissues of the plants as one of lignocellulose materials. Many bacteria secrete enzymes to lyse lignin, which can be essential to eas...

    Authors: Subhashree Rath, Manish Paul, Hemanta Kumar Behera and Hrudayanath Thatoi
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:2
    Content type: Research Published on:

  9. In the present study, adaptive laboratory evolution was used to stimulate antibiotic production in a Streptomyces strain JB140 (wild-type) exhibiting very little antimicrobial activity against bacterial pathogens...

    Authors: Dharmesh Harwani, Jyotsna Begani, Sweta Barupal and Jyoti Lakhani
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:1
    Content type: Research Published on:

  10. Autoinflammatory disorders are the group of inherited inflammatory disorders caused due to the genetic defect in the genes that regulates innate immune systems. These have been clinically characterized based o...

    Authors: Abhinav Jain, Rahul C. Bhoyar, Kavita Pandhare, Anushree Mishra, Disha Sharma, Mohamed Imran, Vigneshwar Senthivel, Mohit Kumar Divakar, Mercy Rophina, Bani Jolly, Arushi Batra, Sumit Sharma, Sanjay Siwach, Arun G. Jadhao, Nikhil V. Palande, Ganga Nath Jha…
    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:183
    Content type: Research Published on:

  11. Many species of mushroom contain an assortment of free radical scavengers (Phenolics and Flavonoids compounds) that have made them nutritionally beneficial and a source of expansion of drug production. In this...

    Authors: Amal I. Hassan, Mona A. M. Ghoneim, Manal G. Mahmoud and Mohsen S. Asker
    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:182
    Content type: Research Published on:

  12. The Pehuén or Monkey puzzle tree (Araucaria araucana) is an evergreen coniferous tree, which has been historically used for social, medicinal, and nutritional purposes. We have recently showed the value of A. ara...

    Authors: María C. Gallia, Julieta Echeverri Del Sarto and Guillermina A. Bongiovanni
    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:181
    Content type: Research Published on:

  13. Despite a reduction in global HIV prevalence the development of a pipeline of new therapeutics or pre-exposure prophylaxis to control the HIV/AIDS epidemic are of high priority. Antibody-based therapies offer ...

    Authors: Advaita Acarya Singh, Priyen Pillay, Lusisizwe Kwezi and Tsepo Lebiletsa Tsekoa
    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:180
    Content type: Short Communications Published on:

  14. Various bacteria promote plant root growth in the rhizosphere, as a measure of securing and enlarging their ecological niche. These interactions are mediated by plant growth regulators (PGRs) such as auxin, an...

    Authors: Seunghye Park, A-Leum Kim, Yoon-Kyung Hong, Ji-Hwan Shin and Se-Hwan Joo
    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:179
    Content type: Research Published on:

  15. Finger millet is the most important food grain in the world for its nutritional benefits. Finger millet is genetically and geographically diverse and widely spread in the African and Asian sub-continent. There...

    Authors: Jayalakshmi Venkatesan, Vasuki Ramu, Thilaga Sethuraman, Chandrasekaran Sivagnanam and Ganesh Doss
    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:178
    Content type: Research Published on:

  16. Leaf senescence occurs in an age-dependent manner, but the rate and timing of leaf senescence may be influenced by various biotic and abiotic factors. In the course of stress, the function, composition, and di...

    Authors: Shamsu Ado Zakari, Syed Hassan Raza Zaidi, Mustapha Sunusi and Kabiru Dawaki Dauda
    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:177
    Content type: Research Published on:

  17. Polycystic ovary syndrome (PCOS) is a chronic endocrine disorder prevalent in premenopausal women and is characterized by a range of physiological and biochemical abnormalities which may include reproductive, ...

    Authors: Fehintoluwa Joy Femi-Olabisi, Ahmed Adebayo Ishola, Opeyemi Faokunla, Anthonia Oluyemi Agboola and Benjamin Ayodipupo Babalola
    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:176
    Content type: Research Published on:

  18. Gerbera jamesonii Bolus ex Hooker f. (African daisy) is listed among the top five most important ornamental plants in the global floricultural industry. To satisfy its demand, the floriculture industry relies on...

    Authors: Saikat Gantait and Manisha Mahanta
    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:175
    Content type: Research Published on:

  19. Orthotropic liver transplantation (OLT) offers a therapeutic choice for hepatocellular carcinoma (HCC) patients. The poor outcome of liver transplantation is HCV recurrence. Several genome-wide associated stud...

    Authors: Ghada M. Salum, Mai Abd el Meguid, Tawfeek H. Abelhafez, Eman Medhat, Ashraf O. Abdel Aziz and Reham Dawood
    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:174
    Content type: Research Published on:

  20. The era of first green revolution brought about by the application of chemical fertilizers surely led to the explosion of food grains, but left behind the notable problem of salinity. Continuous application of...

    Authors: Mandeep Singh, Usha Nara, Antul Kumar, Anuj Choudhary, Hardeep Singh and Sittal Thapa
    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:173
    Content type: Review Published on:

  21. Since the index case was reported in China, COVID-19 has led to the death of at least 4 million people globally. Although there are some vaccine cocktails in circulation, the emergence of more virulent variant...

    Authors: Tolulope Peter Saliu, Haruna I. Umar, Olawale Johnson Ogunsile, Micheal O. Okpara, Noriyuki Yanaka and Olusola Olalekan Elekofehinti
    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:172
    Content type: Research Published on:

  22. Biotechnological breeding of elite sugarcane cultivars is currently limited because of the difficulty of regenerating plants by tissue culture. Here, we report that commercially elite sugarcane genotypes, whic...

    Authors: Valentina Di Pauli, Paola Daniela Fontana, Dalia Marcela Lewi, Arturo Felipe and Luis Ernesto Erazzú
    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:171
    Content type: Research Published on:

  23. Insulin-like growth factor 2 (IGF2) is one of three hormones that share high structural similarity to insulin. It is involved in several insulin-like growth-regulating and mitogenic activities. This study was con...

    Authors: Dhafer A. Ali, Mohammed Baqur S. Al-Shuhaib, Golzar Farhadi, Fadhil R. Al-Kafajy, Tahreer M. Al-Thuwaini and Ali Esmailizadeh
    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:170
    Content type: Research Published on:

  24. Genetic variants in the transcription factor 7-like 2 (TCF7L2) gene are related with type 2 diabetes (T2D) and gestational diabetes mellitus (GDM) in various populations, but there are not enough statistics regar...

    Authors: Taghreed A. Shalabi, Khalda S. Amr and Mai M. Shaker
    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:169
    Content type: Research Published on:

  25. The coexistence of cirrhosis complicates the early detection of hepatocellular carcinoma (HCC). Thus, novel biomarkers for HCC early detection are needed urgently. Traditionally, HCC detection is carried out b...

    Authors: Mohamed M. Omran, Sara Mosaad, Tarek M. Emran, Fathy M. Eltaweel and Khaled Farid
    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:168
    Content type: Research Published on:

  26. Nitrogen and potassium are crucial supplements for plant development and growth. Plants can detect potassium and nitrate ions in soils and in like way, they modify root-to-shoot transport of these ions to adju...

    Authors: Md. Qamrul Islam, Md. Nazmul Hasan, Hammadul Hoque, Nurnabi Azad Jewel, Md. Fahmid Hossain Bhuiyan and Shamsul H. Prodhan
    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:167
    Content type: Research Published on:

  27. Wild medicinal plants are suffering natural environmental stresses and habitat destruction. The genetic diversity evaluation of wild accessions and their in vitro raised genotypes using molecular markers, as w...

    Authors: Abdelfattah Badr, Hanaa H. El-Shazly, Mahmoud Sakr, Mai M. Farid, Marwa Hamouda, Eman Elkhateeb and Hanan Syed Ahmad
    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:166
    Content type: Research Published on:

  28. Several vaccines have been fast-tracked in an attempt to decrease the morbidity and mortality of COVID-19. However, post-exposure prophylaxis has been overlooked in battling COVID-19.

    Authors: Antoine AbdelMassih, Rafeef Hozaien, Meryam El Shershaby, Aya Kamel, Habiba-Allah Ismail, Mariem Arsanyous, Nadine El-Husseiny, Noha Khalil, Youstina Naeem and Raghda Fouda
    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:165
    Content type: Short Communications Published on:

  29. Serine/threonine kinase 3 (AKT3) is a protein-coding gene that is associated with several cattle immune diseases including different tumors and cancers. The objective of this study was to investigate the differen...

    Authors: Farmanullah Farmanullah, Mostafa Gouda, Zhang Min, Xu Sutong, Mohib Ullah KaKar, Sami Ullah Khan, Muhammad Salim, Momen Khan, Zia ur Rehman, Hira Sajjad Talpur, Faheem Ahmed Khan, Nuruliarizki Shinta Pandupuspitasari and Zhang Shujun
    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:164
    Content type: Research Published on:

  30. Pi-ta is a major blast resistant gene, introgressed from indica rice varieties. In this study, diversity of the Pi-ta gene of 47 Sri Lankan rice accessions was studied by bioinformatics, and the results were vali...

    Authors: Suvanthini Terensan, H. Nishadi S. Fernando, J. Nilanthi Silva, S. A. Chandrika N. Perera, Nisha S. Kottearachchi and O. V. D. S. Jagathpriya Weerasena
    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:163
    Content type: Research Published on:

  31. The ocean is one of the world’s most important sources of bioactive chemicals in the marine environment. Microbiologists, ecologists, agronomists, taxonomists, and evolutionary biologists have been increasingl...

    Authors: Sahar Saleh Mohamed, Sayeda Abdelrazek Abdelhamid and Radwa Hassaan Ali
    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:162
    Content type: Review Published on:

  32. Moscatilin is a bibenzyl derivative (stilbenoid), mainly found in Dendrobium species. This plant-derived chemical is a potential cytotoxic anticancer drug that acts against different cancer types. The present stu...

    Authors: Ipsita Pujari, Ritobrata Sengupta and Vidhu Sankar Babu
    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:161
    Content type: Research Published on:

  33. In silico analysis of transcription start sites, promoter regions, transcription factors and their binding sites, and CpG islands for the Trametes hirsuta strain 072 genome were performed to understand the regula...

    Authors: Dinku Senbeta and Mulugeta Kebede
    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:160
    Content type: Research Published on:

  35. Chronic kidney Failure (CKD), particularly End-Stage Renal Disease (ESRD), may be serious ill-health related to a high death rate. Uremic syndrome leads to increased oxidative stress, inflammation, and dyslipi...

    Authors: Afaf Elsaid, Omnia Samir eid, Samy B. Said and Rasha F. Zahran
    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:158
    Content type: Research Published on:

  36. It remains essential for non-alcoholic fatty liver (NAFLD) patients, to develop a sensitive and specific diagnostic model. Data regarding the use of micro (mi)RNA-34 for NAFLD diagnosis are few. Routine clinic...

    Authors: Amal A. Mohamed, Ahmed El-Demery, Eman Al-Hussain, Shroouk Mousa, Ahmed Abdel Halim, Sahar M. Mostafa, Reda S. Abdelghany, Seham M. Mahmoud, Mohammad A. Elkady, Khaled Raafat, Alshymaa A. Hassnine and Mohamed M. Omran
    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:157
    Content type: Research Published on:

  37. Penicillin G amidase/acylases from microbial sources is a unique enzyme that belongs to the N-terminal nucleophilic hydrolase structural superfamily. It catalyzes the selective hydrolysis of side chain amide/a...

    Authors: Krishika Sambyal and Rahul Vikram Singh
    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:156
    Content type: Review Published on:

  38. Difficult to express peptides are usually produced by co-expression with fusion partners. In this case, a significant mass part of the recombinant product falls on the subsequently removed fusion partner. On t...

    Authors: Murad Mollaev, Artur Zabolotskii, Neonila Gorokhovets, Elena Nikolskaya, Maria Sokol, Andrey Tsedilin, Mariia Mollaeva, Margarita Chirkina, Timofey Kuvaev, Anna Pshenichnikova and Nikita Yabbarov
    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:155
    Content type: Research Published on:

  39. Hepatitis E is a liver disease caused by the pathogen hepatitis E virus (HEV). The largest polyprotein open reading frame 1 (ORF1) contains a nonstructural Y-domain region (YDR) whose activity in HEV adaptatio...

    Authors: Zoya Shafat, Anwar Ahmed, Mohammad K. Parvez and Shama Parveen
    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:154
    Content type: Research Published on:

  40. Mastitis is one of the major diseases causing economic loss to the dairy industry by reducing the quantity and quality of milk. Thus, the objective of this scientific study was to find new biomarkers based on ...

    Authors: Farmanullah Farmanullah, Xianwei Liang, Faheem Ahmed Khan, Mohammad Salim, Zia ur Rehman, Momen Khan, Hira Sajjad Talpur, N. M. Schreurs, Mostafa Gouda, Sami Ullah Khan and Zhang Shujun
    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:153
    Content type: Research Published on:

  41. Mining for precious metals is detrimental to the composition of soil structure and microbial diversity distribution and is a health risk to human communities around the affected communities. This study was aim...

    Authors: U. B. Ibrahim, A. H. Kawo, I. Yusuf and S. Yahaya
    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:152
    Content type: Research Published on:

  42. To develop new breeding technology to improve the breeding ability of bovine, it is the development trend to find the main reason for the occurrence of atresia in these organisms. Transcriptomes of small (100–...

    Authors: Khairy Mohamed Zoheir, Ahmed Mohamed Darwish, Yang Liguo and Abdelkader E. Ashour
    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:151
    Content type: Research Published on:

  43. Impact of interleukin 28B (IL28B) rs12979860 polymorphism on response to direct-acting antivirals agents in HCV genotype 4-infected patients is under investigation. Zinc may have an advantage in improvement of li...

    Authors: Abdelfattah M. Attallah, Dalia Omran, Mohamed A. Abdelrazek, Mohamed Hassany, Sameh Saif, Aza Farid, Riham El Essawey, Muhammad Abdel Ghaffar, Marwa Aabdelghany and Ayman Yosry
    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:150
    Content type: Research Published on:

  44. Soil pollution by heavy metals increases the bioavailability of metals like hexavalent chromium (Cr (VI)), subsequently limiting plant growth and reducing the efficiency of phytoremediation. Plant growth-promo...

    Authors: Nabil Tirry, Aziza Kouchou, Bouchra El Omari, Mohamed Ferioun and Naïma El Ghachtouli
    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:149
    Content type: Research Published on:

  46. Metabolic syndrome is defined as a group of interrelated biochemical, clinical, and metabolic factors that directly increase the risk of cardiovascular disease, obesity, and type 2 diabetes mellitus. MicroRNA-...

    Authors: Miral M. Refeat, Naglaa Abu-Mandil Hassan, Inass Hassan Ahmad, Eman Roshdy Mohamed Mostafa and Khalda S. Amr
    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:147
    Content type: Research Published on:

  47. Chromobacterium species, through their bioactive molecules, help in combating biotic and abiotic stresses in plants and humans. The present study was aimed to identify, characterize and preserve in natural gums t...

    Authors: Sushil K. Sharma, Rakhi Dhyani, Ees Ahmad, Pankaj K. Maurya, Madhu Yadav, Ramesh Chandra Yadav, Vinod Kumar Yadav, Pawan K. Sharma, Mahaveer P. Sharma, Aketi Ramesh and Anil K. Saxena
    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:146
    Content type: Research Published on:

  48. Potato (Solanum tuberosum L.) is one of the most important food crops in the world. Pathogens remain as one of the major constraints limiting potato productivity. Thus, understanding of gene regulation mechanism ...

    Authors: Atnafu Kebede and Mulugeta Kebede
    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:145
    Content type: Research Published on:

  49. Rosa damascena Mill is a well-known species of the rose family. It is famous for its essential oil content. The aim of the present study was to assess the genetic diversity and population structure of a mini core...

    Authors: Atefeh Sadat Mostafavi, Mansour Omidi, Reza Azizinezhad, Alireza Etminan and Hassanali Naghdi Badi
    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:144
    Content type: Research Published on:

  50. Hydrolysis of cellulose-based biomass by cellulases produce fermented sugar for making biofuels, such as bioethanol. Cellulases hydrolyze the β-1,4-glycosidic linkage of cellulose and can be obtained from cult...

    Authors: Rahmat Eko Sanjaya, Kartika Dwi Asni Putri, Anita Kurniati, Ali Rohman and Ni Nyoman Tri Puspaningsih
    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:143
    Content type: Research Published on:
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  • ISSN: 2090-5920 (electronic)