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Journal of Genetic Engineering and Biotechnology
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  1. Periodontitis is a multi-factorial infection with red complex bacteria playing a crucial role in the pathogenesis. As bacteria are tending to develop resistance against conventional antibiotics, new treatment ...

    Authors: Harini Venkata Subbiah, Polani Ramesh Babu and Usha Subbiah
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:59
    Content type: Research Published on:

  2. The recent severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection cause high mortality and there is an emergency need to develop a specific drug to treat the novel coronavirus disease, COVID-19...

    Authors: Ravichandran Veerasamy and Rohini Karunakaran
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:58
    Content type: Research Published on:

  3. The enormous and irresponsible use of antibiotics has led to the emergence of resistant strains of bacteria globally. A new approach to combat this crisis has been nutritional immunity limiting the availabilit...

    Authors: Anil H. Shyam Mohan, Saroja Narsing Rao, Srividya D. and N. Rajeswari
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:57
    Content type: Research Published on:

  4. Hepatitis E virus (HEV) is a positive-sense RNA virus belonging to the family Hepeviridae. The genome of HEV is organized into three open-reading frames (ORFs): ORF1, ORF2, and ORF3. The ORF1 non-structural Y-d...

    Authors: Zoya Shafat, Anwar Ahmed, Mohammad K. Parvez and Shama Parveen
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:56
    Content type: Research Published on:

  5. Mycobacterium tuberculosis has been ravaging humans by inflicting respiratory tuberculosis since centuries. Bacillus Calmette Guerine (BCG) is the only vaccine available for tuberculosis, and it is known to be p...

    Authors: Kaviya Parambath Kootery and Suma Sarojini
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:55
    Content type: Research Published on:

  6. Salmonella enterica serovar Typhimurium (S. Typhimurium) causes gastroenteritis and diarrhea in humans and food-producing animals. The type III secretion system (T3SS) has been known to be a potent virulence mec...

    Authors: Rerngwit Boonyom, Sittiruk Roytrakul and Patipat Thinwang
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:54
    Content type: Research Published on:

  7. Mycobacterium colombiense is an acid-fast, non-motile, rod-shaped mycobacterium confirmed to cause respiratory disease and disseminated infection in immune-compromised patients, and lymphadenopathy in immune-comp...

    Authors: Feyissa Hamde, Hunduma Dinka and Mohammed Naimuddin
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:53
    Content type: Research Published on:

  8. Sphingomonas wittichii RW1 is one out of three strains capable of metabolizing dioxin as a sole source for carbon and energy. Under laboratory conditions the degradation rates for these aromatics are relatively h...

    Authors: Rayan M. Faisal and Aveen H. Rasol
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:52
    Content type: Research Published on:

  9. The nitrile compounds are produced either naturally or synthetically and are highly used in many manufacturing industries such as pharmaceuticals, pesticides, chemicals, and polymers. However, the extensive us...

    Authors: M. Amrutha and K. Madhavan Nampoothiri
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:51
    Content type: Research Published on:

  10. Thermo-alkali stable xylanases were purified from the extracellular broth of newly isolated Bacillus licheniformis strain produced in a 5-L stirred-tank bioreactor with wheat bran as a carbon source.

    Authors: Girisha Malhotra and Shilpa S. Chapadgaonkar
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:50
    Content type: Research Published on:

  11. Increase of antibiotic resistance in pathogenic microbes necessitated novel molecules for curing infection. Antimicrobial peptides (AMPs) are the gene-encoded evolutionarily conserved small molecules with ther...

    Authors: P. P. Athira, V. V. Anooja, M. V. Anju, S Neelima, K. Archana, S. Muhammed Musthafa, Swapna P. Antony, I. S. Bright Singh and Rosamma Philip
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:49
    Content type: Research Published on:

  13. Leukemia inhibitory factor (LIF) is a multifunctional cytokine which plays multiple roles in different biological processes such as implantation, bone remodeling, and hematopoiesis. The buESCs are difficult to...

    Authors: Shradha Jamwal, Shama Ansari, Dhruba Malakar, Jai Kumar Kaushik, Sudarshan Kumar and Ashok Kumar Mohanty
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:47
    Content type: Research Published on:

  14. The Philippines is among the top 10 major exporters of mango worldwide. However, genomic studies of Philippine mangoes remain largely unexplored and lacking. Here, we sequenced the whole genome of the three Ph...

    Authors: Cris Q. Cortaga, John Albert P. Lachica, Darlon V. Lantican and Eureka Teresa M. Ocampo
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:46
    Content type: Research Published on:

  15. Tomatoes (Solanum lycopersicon L.) are one of the main daily consumed vegetables in the human diet. Tomato has been classified as moderately sensitive to salinity at most stages of plant development, including se...

    Authors: Ibrahim M. Makhadmeh, Samar G. Thabet, Mohammed Ali, Basmah Alabbadi, Ammar Albalasmeh and Ahmad M. Alqudah
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:45
    Content type: Research Published on:

  16. Methyl CpG binding protein 2 (MeCP2) is essential for the normal function of mature neurons. Mutations in the MECP2 gene are the main cause of Rett syndrome (RTT). Gene mutations have been identified throughou...

    Authors: Wessam E. Sharaf-Eldin, Mahmoud Y. Issa, Maha S. Zaki, Ayman Kilany and Alaaeldin G. Fayez
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:44
    Content type: Research Published on:

  17. The derivatives of quercetin is known for their immune-modulating antiviral, anti-blood clotting, antioxidant, and also for its anti-inflammatory efficacy. The current study was therefore conducted to examine ...

    Authors: Kunal Bhattacharya, Ripunjoy Bordoloi, Nongmaithem Randhoni Chanu, Ramen Kalita, Bhargab Jyoti Sahariah and Atanu Bhattacharjee
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:43
    Content type: Research Published on:

  18. Efforts toward the development of an effective vaccine against Acinetobacter baumannii, one of the most notorious nosocomial pathogens, are still ongoing. In this regard, virulence factors are interesting targets...

    Authors: Saeed Alipouri, Iraj Rasooli, Mohammad Hossein Ghaini, Abolfazl Jahangiri, Shakiba Darvish Alipour Astaneh and Fatemeh Ramezanalizadeh
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:42
    Content type: Research Published on:

  19. The Tropheryma whipplei causes acute gastroenteritis to neuronal damages in Homo sapiens. Genomics and codon adaptation studies would be helpful advancements of disease evolution prediction, prevention, and treat...

    Authors: Amit Joshi, Sunil Krishnan and Vikas Kaushik
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:41
    Content type: Research Published on:

  20. Piper hispidinervum is a species native from the Amazon region with great economic potential, given its scientifically proven insecticidal properties. In this study, an efficient protocol of plant regeneration v...

    Authors: Paulo Cesar Alves de Sousa, Stênio Steferson Silva e Souza, Gabriela Ferreira Nogueira, Inaê Mariê de Araújo Silva-Cardoso and Jonny Everson Scherwinski-Pereira
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:40
    Content type: Research Published on:

  21. Durian of Indonesia, specifically Durio zibethinus, is a potential agricultural commodity for domestic and international markets. However, its quality is still less competitive or significantly lower to fulfill t...

    Authors: Dindin Hidayatul Mursyidin, Muhammad Irfan Makruf, Badruzsaufari and Aidi Noor
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:39
    Content type: Research Published on:

  22. Microalgae have tremendous potential in CO2 sequestration, bioenergy, biofuels, wastewater treatment, and high-value metabolites production. However, large-scale production of microalgae is hampered due to photo-...

    Authors: Jayant Pralhad Rathod, Chaitali Vira, Arvind M. Lali and Gunjan Prakash
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:38
    Content type: Research Published on:

  23. No doubt that the corpus luteum (CL) plays a vital role in the regulation of female cyclicity in mammals. The scenarios among microRNAs (miRNAs) and their target genes and steroid hormones {estradiol (E2) and ...

    Authors: Sally Ibrahim, Mohamed O. Taqi, A. S. A. Sosa, Al-Shimaa Al-H. H. El-Naby, Karima Gh. M. Mahmoud, Hassan R. H. Darwish, Amal R. Abd El Hameed and M. F. Nawito
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:37
    Content type: Research Published on:

  24. α-Galactosidase is widely distributed in plants, microorganisms, and animals, and it is produced by different fungal sources. Many studies have confirmed the valuable applications of α-galactosidase enzymes fo...

    Authors: Ali M. Elshafei, Abdelmageed M. Othman, Maysa A. Elsayed, Gamil E. Ibrahim, Mohamed M. Hassan and Nayra S. Mehanna
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:36
    Content type: Research Published on:

  26. Cellulose is the most prevalent biomass and renewable energy source in nature. The hydrolysis of cellulosic biomass to glucose units is essential for the economic exploitation of this natural resource. Cellula...

    Authors: Zainab E. Elsababty, Samir H. Abdel-Aziz, Atef M. Ibrahim, Adel A. Guirgis and Ghada E. Dawwam
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:34
    Content type: Research Published on:

  27. Cerium-containing materials have wide applications in the biomedical field, because of the mimetic catalytic activities of cerium. The study aims to deeply estimate the biocompatibility of different scaffolds ...

    Authors: Hanan F. Hammouda, Mohammad M. Farag, Mervat M. F. El Deftar, M. Abdel-Gabbar and Basant M. Mohamed
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:33
    Content type: Research Published on:

  28. The increased demand for oil and fats to satisfy the ever-increasing human needs has enhanced the research in this field. Single-cell oils or microbial lipids produced by oleaginous microorganisms are being ut...

    Authors: Mohamed E. Osman, Asharf Bakery Abdel-Razik, Khaled I. Zaki, Nesma Mamdouh and Heba El-Sayed
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:32
    Content type: Research Published on:

  29. The B30.2 variants lead to most relevant severity forms of familial Mediterranean fever (FMF) manifestations. The B30.2 domain plays a key role in protein-protein interaction (PPI) of pyrin with other apoptosi...

    Authors: Alaaeldin G. Fayez, Ghada Nour Eldeen, Waheba A. Zarouk, Khaled Hamed, Abeer Ramadan, Bardees M. Foda, Maha M. Kobesiy, Mai E. Zekrie, Randa S. Lotfy, Mona F. Sokkar and Hala T. El-Bassyouni
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:31
    Content type: Research Published on:

  30. The role of atrial natriuretic peptide (ANP) in edema formation in idiopathic nephrotic syndrome (INS) was studied before with conflicting results reported; however, the possible contribution of genes regulati...

    Authors: Hanan El-Halaby, Ashraf Bakr, Riham Eid, Hussein Abdelaziz Abdalla, Nashwa Hamdy, Nora Shamekh, Amira Adel and Ahmed El-Husseiny
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:30
    Content type: Research Published on:

  31. Durian (Durio zibethinus L.) is a tropical fruit crop which is popular in Southeast Asia but recently gaining popularity in other parts of the world. In this study, we analyzed the resistance gene analogs (RGAs) ...

    Authors: Cris Q. Cortaga, Romnick A. Latina, Rosteo R. Habunal and Darlon V. Lantican
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:29
    Content type: Short Communications Published on:

  32. Plant grows in nature facing various types of abiotic stresses for their normal growth and development. During abiotic stress, plants evolve different types of mechanisms to survive in a hostile environment. P...

    Authors: Md. Abu Sadat, Md. Wali Ullah, Md. Sabbir Hossain, Borhan Ahmed and Kazi Khayrul Bashar
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:28
    Content type: Research Published on:

  34. Lactic acid bacteria (LAB) could be used for bio-production of lactic acid (LA) from wastes of dairy industries. This study aimed to produce LA using isolated and identified LAB capable of withstanding high sa...

    Authors: Atiat Sayed Dosuky, Tarek Ragab Elsayed, Eman Tawfik Yousef, Olfat Sayed Barakat and Nasr Fawzy Nasr
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:26
    Content type: Research Published on:

  35. The Plant U-box (PUB), ubiquitin ligase gene, has a highly conserved domain in potato. However, little information is available about U-box genes in potato (Solanum tuberosum). In this study, 62 U-box genes were ...

    Authors: Zahra Hajibarat, Abbas Saidi, Mehrshad Zeinalabedini, Ahmad Mosuapour Gorji, Mohammad Reza Ghaffari, Vahid Shariati and Rahim Ahmadvand
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:25
    Content type: Research Published on:

  36. The present study focuses on the isolation of Bacillus thuringiensis bacterium from the gut of fresh water fish, Systomus sarana, the innovative optimization of culture parameters to produce maximum protease enzy...

    Authors: Arul Dhayalan, Balasubramanian Velramar, Balasubramani Govindasamy, Karthik Raja Ramalingam, Aiswarya Dilipkumar and Perumal Pachiappan
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:24
    Content type: Research Published on:

  37. Amylase is used commercially in food, textiles, sugar syrup, paper, and detergent industries. Bacteria and fungi remain a significant source of industrial enzymes. Pleurotus tuberregium is a macro-fungi that can ...

    Authors: Comfort Olukemi Bamigboye, Raphael E. Okonji, Iyanu Oluwalonimi Oluremi and Victoria James
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:23
    Content type: Research Published on:

  38. This study targets the enhanced production of l-asparaginase, an antitumor enzyme by Acinetobacter baumannii ZAS1. This organism is an endophyte isolated from the medicinal plant Annona muricata. Plackett–Burman ...

    Authors: K. N. Abhini, Akhila B. Rajan, K. Fathimathu Zuhara and Denoj Sebastian
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:22
    Content type: Research Published on:

  39. Oxidative stress is among the most common risk factors in the pathogenesis of acute myocardial infarction (AMI). Glutathione peroxidase 1 enzyme coded by the GPX1 gene plays an essential role in reducing oxidativ...

    Authors: Lamia K. Ismail, Mohamed F. Abdel Rahman, Ingy M. Hashad and Sahar M. Abdel-Maksoud
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:21
    Content type: Research Published on:

  40. Wadi El Natrun microorganisms have been considered as a new resource for natural products due to its extreme condition of salinity and alkalinity. Therefore, this study was devoted to generate metagemic librar...

    Authors: Safaa M. Ali, Nadia A. Soliman, Samia Abd Allah Abdal-Aziz and Yasser R. Abdel-Fattah
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:20
    Content type: Research Published on:

  41. A major discovery in human etiology recognized that cervical cancer is a consequence of an infection caused by some mucosatropic types of human papillomavirus (HPV). Since L1 protein of HPV is able to induce t...

    Authors: Apon Zaenal Mustopa, Lita Meilina, Shasmita Irawan, Nurlaili Ekawati, Alfi Taufik Fathurahman, Lita Triratna, Arizah Kusumawati, Anika Prastyowati, Maritsa Nurfatwa, Ai Hertati and Rikno Harmoko
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:19
    Content type: Research Published on:

  42. The primary amino acid sequence of a protein is a translated version from its gene sequence which carries important messages and information concealed therein. The present study unveils the structure-function ...

    Authors: Krishnendu Pramanik and Narayan Chandra Mandal
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:18
    Content type: Research Published on:

  43. Diabetic retinopathy (DR) is a common microvascular complication of diabetes. There is strong evidence suggesting that DR has an inheritable component. The interaction between advanced glycation end products (...

    Authors: Pragya Ahuja, Abdul Waris, Sheelu Shafiq Siddiqui and Amit Mukherjee
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:17
    Content type: Review Published on:

  44. Castor bean (Ricinus communis L.) is an important cultivated oilseed. Seeds contain ricinoleic acid, a valuable product for a variety of industries. Castor cake is a residue of ricinoleic manufacture and could be...

    Authors: Natália L. de Sousa, Glaucia B. Cabral and Francisco J. L. Aragão
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:16
    Content type: Short Communications Published on:

  45. Mitochondrial complex ΙΙ has a unique biological role owing to its participation in both the citric acid cycle and the electron transport chain. Our goal was to evaluate the succinate dehydrogenase and ubiquin...

    Authors: Eman M. Ragab, Doaa M. El Gamal, Tarek M. Mohamed and Abeer A. Khamis
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:15
    Content type: Research Published on:

  46. The marine environment hosts a wide variety of species that have evolved to live in harsh and challenging conditions. Marine organisms are the focus of interest due to their capacity to produce biotechnologica...

    Authors: Akash Karthikeyan, Abey Joseph and Baiju G. Nair
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:14
    Content type: Review Published on:

  47. Association between Helicobacter pylori (H. pylori) and chronic hepatitis C (CHC) still remains controversial. This work is concerned with assessing the potential role of H. pylori in the progression of hepatitis...

    Authors: Abdelfattah M. Attallah, Mohamed S. Albannan, Mohamed F. Ghaly, Sally E. Sallam, Mahmoud M. Amer and Attia A. Attia
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:13
    Content type: Research Published on:

  48. Although microbial fuel cells (MFCs) represent a promising technology for capturing renewable energy from wastewater, their scaling-up is significantly limited by a slow-rate cathodic oxygen reduction reaction...

    Authors: Dena Z. Khater, R. S. Amin, M. O. Zhran, Zeinab K. Abd El-Aziz, Mohamed Mahmoud, Helmy M. Hassan and K. M. El-Khatib
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:12
    Content type: Research Published on:

  49. Essential hypertension (EH) is an important risk factor for various cardiovascular, cerebral and renal disorders. It is a multi-factorial trait which occurs through complex interplay between genetic, epigeneti...

    Authors: Mayank Chaudhary
    Citation: Journal of Genetic Engineering and Biotechnology 2022 20:11
    Content type: Review Published on:
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  • ISSN: 2090-5920 (electronic)