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Journal of Genetic Engineering and Biotechnology
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  1. Potato (Solanum tuberosum L.) is one of the most important food crops in the world. Pathogens remain as one of the major constraints limiting potato productivity. Thus, understanding of gene regulation mechanism ...

    Authors: Atnafu Kebede and Mulugeta Kebede
    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:145
    Content type: Research Published on:

  2. Hydrolysis of cellulose-based biomass by cellulases produce fermented sugar for making biofuels, such as bioethanol. Cellulases hydrolyze the β-1,4-glycosidic linkage of cellulose and can be obtained from cult...

    Authors: Rahmat Eko Sanjaya, Kartika Dwi Asni Putri, Anita Kurniati, Ali Rohman and Ni Nyoman Tri Puspaningsih
    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:143
    Content type: Research Published on:

  3. Mung bean is a pulse crop principally grown in the tropic and subtropic parts of the world for its nutrient-rich seeds. Seven mung beans accessions from Eastern Kenya were evaluated using thirteen phenotypic t...

    Authors: Jedidah Wangari Mwangi, Oduor Richard Okoth, Muchemi Peterson Kariuki and Ngugi Mathew Piero
    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:142
    Content type: Research Published on:

  4. Livin/BIRC7 is a member of the inhibitors of apoptosis proteins family which are implicated in development of cancer through the inhibition of apoptosis process. This case-control study was intended to investigat...

    Authors: Basma K. Elmekkawy, Rasha M. S. Shoaib, Amal K. Seleem, Dalia Shaalan and Entsar A. Saad
    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:141
    Content type: Research Published on:

    The Correction to this article has been published in Journal of Genetic Engineering and Biotechnology 2022 20:27

  5. Bacterial biofilms are aggregation or collection of different bacterial cells which are covered by self-produced extracellular matrix and are attached to a substratum. Generally, under stress or in unfavorable...

    Authors: Shivani Singh, Saptashwa Datta, Kannan Badri Narayanan and K. Narayanan Rajnish
    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:140
    Content type: Review Published on:

  6. Cardiovascular disease (CVD) remains the major cause of death worldwide. Most CVD can be prevented by addressing risk factors. Acute myocardial infarction (AMI) is an inflammatory disorder characterized by cha...

    Authors: Ingy M. Hashad, Habiba Nosseir, Gamal M. Shaban, Mohamed F. Abdel Rahman and Mohamed Z. Gad
    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:139
    Content type: Research Published on:

  7. As the body of scientific research focusing on the severe acute respiratory syndrome coronavirus 2 or SARS-CoV-2 continues to grow, several mutations have been reported as very common across the globe. In this...

    Authors: Syeda Tasnim Quayum and Saam Hasan
    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:138
    Content type: Short Communications Published on:

  8. This work investigates the production of citric acid from cashew apple juice, an abundant waste in the processing of cashew, using a local strain of Aspergillus niger and the application of the citric acid as a c...

    Authors: Adekunle Olusegun Adeoye and Agbaje Lateef
    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:137
    Content type: Research Published on:

  9. The present study reports metagenomic sequencing and microbial diversity analysis of the sediment samples of a semi-intensive penaeid shrimp culture system. 16S rRNA gene-based high-throughput sequencing revea...

    Authors: M. S. Chithira, P. V. Aishwarya, Anjali S. Mohan and Swapna P. Antony
    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:136
    Content type: Short Communications Published on:

  10. Protoplasts (i.e., naked plant cells) can be used for in vitro manipulations and genetic improvement in cultivars with economic value. During the last decade, protoplast research in economic brown algae has be...

    Authors: Jose Avila-Peltroche, Boo Yeon Won and Tae Oh Cho
    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:135
    Content type: Research Published on:

  11. The recent recovery of Gyrinops walla as a potential producer of market-quality agarwood in mature damaged woods and branches has led to the intense illicit felling and exportation of G. walla leading to the verg...

    Authors: Sachithri Munasinghe, Seneviratnege Somaratne, Shyama Weerakoon and Chandani Ranasinghe
    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:134
    Content type: Research Published on:

  12. Amoebiasis, being endemic worldwide, is the second leading cause of parasite-associated morbidity and mortality after malaria. The human parasite Entamoeba histolytica is responsible for the disease. Metronidazol...

    Authors: Suchetana Pal, Pinaki Biswas, Raktim Ghosh and Somasri Dam
    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:133
    Content type: Research Published on:

  13. Vitiligo is a common pigmentary disorder in which autoimmunity has been suggested to play an important role. Toll-like receptor (TLR) family are recognized different molecular structures expressed on immune ce...

    Authors: Maha Abdelsalam, Sherihan H. Allam, Marwa Zohdy, Hend Magdy and Maged Mostafa
    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:132
    Content type: Research Published on:

  14. The aim of this work was to synthesize copper oxide nanoparticles (CuO NPs) utilizing heartwood aqueous extract of Suaeda maritima (L.) Dumort. The synthesis of CuO NPs using green methodology with small size and...

    Authors: Pavani Peddi, Prasada Rao PTSRK, Nannapaneni Usha Rani and S. Lakshmi Tulasi
    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:131
    Content type: Research Published on:

  15. In resource-limited countries, ABO, HLA, MNS, Kells, and hemoglobin electrophoresis are classic tests for the resolution of paternity disputes due to their affordable cost. The limitations of these tests in ca...

    Authors: Missa Millogo, Serge Theophile Soubeiga, Bapio Valerie Jean Telesphore Bazie, Theodora Mahoukede Zohoncon, Abdoul Karim Ouattara, Albert Theophane Yonli and Jacques Simpore
    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:130
    Content type: Research Published on:

  17. DNA markers improved the productivity and accuracy of classical plant breeding by means of marker-assisted selection (MAS). The enormous number of quantitative trait loci (QTLs) mapping read for different plan...

    Authors: Nazarul Hasan, Sana Choudhary, Neha Naaz, Nidhi Sharma and Rafiul Amin Laskar
    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:128
    Content type: Review Published on:

  18. Tuta absoluta Meyrick 1917 (Lepidoptera: Gelechiidae) is an invasive, pesticide resistant, and a major treat of tomato production in the world. It needs effective management options that naturally infect the inse...

    Authors: Birhan Aynalem, Diriba Muleta, Juan Venegas and Fassil Assefa
    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:127
    Content type: Research Published on:

  19. Nanoparticle synthesis is a very interesting area of research currently due to the wide applications of nanoparticles. The nanoparticles have a diameter ranging between 1 and 100 nm and they are used in differ...

    Authors: Deeksha Chugh, V. S. Viswamalya and Bannhi Das
    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:126
    Content type: Review Published on:

  20. Genome of an organism has always fascinated life scientists. With the discovery of restriction endonucleases, scientists were able to make targeted manipulations (knockouts) in any gene sequence of any organis...

    Authors: Anuradha Bhardwaj and Vikrant Nain
    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:125
    Content type: Review Published on:

  21. Phospholipases hydrolyze glycerophospholipids and generate diverse lipid-derived molecules with secondary messenger activity. Out of these, phospholipase C (PLC) specifically cleaves the phospholipids at ester...

    Authors: Madhvi Kanchan, Thakku R. Ramkumar, Himani and Jaspreet K. Sembi
    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:124
    Content type: Research Published on:

  22. γ-Aminobutyric acid sub-type A receptors (GABAARs) are the most prominent inhibitory neurotransmitter receptors in the CNS. They are a family of ligand-gated ion channel with significant physiological and therape...

    Authors: Amr Ghit, Dina Assal, Ahmed S. Al-Shami and Diaa Eldin E. Hussein
    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:123
    Content type: Review Published on:

  23. Terrestrial orchids belonging to the Orchis genus are difficult to propagate and are under great pressure in their natural habitats. Studies regarding the influence of photoperiod and temperature regimes on Orchi...

    Authors: Aleksandra Yurievna Nabieva
    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:122
    Content type: Research Published on:

  24. Canine circovirus is a deadly pathogen of dogs and causes vasculitis and hemorrhagic enteritis. It causes lethal gastroenteritis in pigs, fox, and dogs. Canine circovirus genome contains two main (and opposite) t...

    Authors: Pankaj Jain, Amit Joshi, Nahid Akhtar, Sunil Krishnan and Vikas Kaushik
    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:121
    Content type: Research Published on:

  25. The present study dealt with the screening of soil bacteria with antibacterial activity from different locations in Bangalore, India. Antibiotics play the role of self-defense mechanism for the bacteria and ar...

    Authors: R. Prashanthi, Shreevatsa G.K., Krupalini S. and Manoj L.
    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:120
    Content type: Research Published on:

  26. Sandwich ELISA is an ideal antigen detection and quantification assay. Recently, it was used as the basic concept for high technology diagnostics. The specificity of the assay depends on the exclusion of detec...

    Authors: Rola Nadeem, Ahmed B. Barakat and Mahmoud M. Bahgat
    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:119
    Content type: Research Published on:

  27. Illicium griffithii is an aromatic medicinal tree species that has been listed in the IUCN Red List as an endangered species. Dried seed pods of I. griffithii have a good market potential in the spices and pharma...

    Authors: Rajib Borah, Atanu Bhattacharjee, Satyawada Rama Rao, Vineet Kumar, Pradeep Sharma, Krishna Upadhaya and Hiranjit Choudhury
    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:118
    Content type: Research Published on:

  28. Oleuropein, the main bitter phenolic glucoside responsible for green olive bitterness, may be degraded by the β-glucosidase enzyme to release glucose and phenolic compounds.

    Authors: Yahya Rokni, Houssam Abouloifa, Reda Bellaouchi, Ismail Hasnaoui, Sara Gaamouche, Zahra Lamzira, Riadh B. E. N. Salah, Ennouamane Saalaoui, Nabil Ghabbour and Abdeslam Asehraou
    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:117
    Content type: Research Published on:

  29. Ovarian cancer causes more deaths than any other cancer of the female reproductive system because there is no effective screening and most women are diagnosed at advanced stages. The probability of survival at...

    Authors: J. N. Nikhitha, K. S. Swathy and R. Pratap Chandran
    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:116
    Content type: Research Published on:

  30. Vitamin D receptor (VDR) is known as one of the cellular regulators for several metabolic pathways indicating its pivotal role in the pathological pathway of numerous diseases. Considering the high frequency o...

    Authors: Nayera E. Hassan, Sahar A. El-Masry, Waheba Ahmed Zarouk, Ghada Nour Eldeen, Rehab M. Mosaad, Mahmoud A. S. Afify, Manal M. Aly and Aya Khalil
    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:115
    Content type: Research Published on:

  31. The health-promoting effects along with global economic importance of consuming food products supplemented with probiotic microorganisms encouraged the researchers to discover new probiotics.

    Authors: Al-Shimaa Ibrahim Ahmed, Gihan Mohamed El Moghazy, Tarek Ragab Elsayed, Hanan Abdel Latif Goda and Galal Mahmoud Khalafalla
    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:114
    Content type: Research Published on:

  32. Targeting viral cell entry proteins is an emerging therapeutic strategy for inhibiting the first stage of SARS-CoV-2 infection. In this study, 106 bioactive terpenoids from African medicinal plants were screen...

    Authors: Gideon A. Gyebi, Oludare M. Ogunyemi, Ibrahim M. Ibrahim, Olalekan B. Ogunro, Adegbenro P. Adegunloye and Saheed O. Afolabi
    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:113
    Content type: Research Published on:

  33. Variants in the signal transducer and activator of transcription 4 (STAT4) gene have an important role in the incident of multiple autoimmune diseases including type 1 diabetes mellitus (T1D). It is a genetica...

    Authors: Samar Samir Abdelmajed, Mohamed A. El-Dessouky, Doaa S. SalahElDin, Naglaa Abu-Mandil Hassan, Moushira Erfan Zaki and Somaia Ismail
    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:112
    Content type: Research Published on:

  34. Mucolipidosis II (ML II α/β) is an inherited lysosomal storage disorder caused by deficiency of GlcNAc-phosphotransferase enzyme and results in mis-targeting of multiple lysosomal enzymes. Affected patients ar...

    Authors: Mona L. Essawi, Ekram M. Fateen, Hanan A. Atia, Noura R. Eissa, Eman H. Aboul-Ezz, Mona M. Ibrahim, Heba A. Hassan and Samia A. Temtamy
    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:111
    Content type: Research Published on:

  35. Pullulanases are the significant industrial group in the 13 glycosyl hydrolases category, known as the α-amylases family. There are very few reports on pullulanase from fungal sources. Based on the above resea...

    Authors: Bindu Naik, S. K. Goyal, Abhishek Dutt Tripathi and Vijay Kumar
    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:110
    Content type: Research Published on:

  36. Insulin-like growth factor-1 (IGF-1) is required for normal intrauterine and postnatal growth, and this action is mediated through IGF1 receptor (IGF1R). IGF1R copy number variants (CNVs) can cause pre- and postn...

    Authors: Islam M. Fadel, Moustafa H. Ragab, Ola M. Eid, Nivine A. Helmy, Hala T. El-Bassyouni and Inas Mazen
    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:109
    Content type: Research Published on:

  37. Anarrhinum pubescens Fresen. (Plantaginaceae) is a rare plant, endemic to the Saint Catherine area, of South Sinai, Egypt. Earlier studies have reported the isolation of cytotoxic and anti-cholinesterase iridoid ...

    Authors: Asmaa Abdelsalam, Ehab Mahran, Kamal Chowdhury and Arezue Boroujerdi
    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:108
    Content type: Research Published on:

  38. Argentina’s geothermal areas are niches of a rich microbial diversity. In 2020, species of Bacillus cytotoxicus were isolated for the first time from these types of pristine natural areas. Bacillus cytotoxicus st...

    Authors: Ivana Cavello, Brenda Bezus and Sebastián Cavalitto
    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:107
    Content type: Research Published on:

  39. The discovery of potential, new cost-effective drug resources in the form of bioactive compounds from mushrooms is one way to control the resistant pathogens. In the present research, the fruiting bodies of fi...

    Authors: Elham R. S. Soliman and Heba El-Sayed
    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:106
    Content type: Research Published on:

  40. Cardiovascular diseases (CVDs) are the leading cause of mortality in India. Residual risk exists in patients receiving optimal guideline-directed medical therapy. Possession of certain somatic mutations, at a ...

    Authors: Nagendra Boopathy Senguttuvan, Vinodhini Subramanian, Vettriselvi Venkatesan, T. R. Muralidharan and Kavitha Sankaranarayanan
    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:105
    Content type: Review Published on:

  41. Accessing COVID-19 vaccines is a challenge despite successful clinical trials. This burdens the COVID-19 treatment gap, thereby requiring accelerated discovery of anti-SARS-CoV-2 agents. This study explored th...

    Authors: Von Novi O. de Leon, Joe Anthony H. Manzano, Delfin Yñigo H. Pilapil IV, Rey Arturo T. Fernandez, James Kyle Anthony R. Ching, Mark Tristan J. Quimque, Jay Carl M. Agbay, Kin Israel R. Notarte and Allan Patrick G. Macabeo
    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:104
    Content type: Research Published on:

  42. Plasmodium falciparum is the most deadly and leading cause of morbidity and mortality in Africa. About 90% of all malaria deaths in the world today occur in Sub-Saharan Africa especially in children aged < 5 year...

    Authors: Claire Aguttu, Brenda Apio Okech, Ambrose Mukisa and George William Lubega
    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:103
    Content type: Research Published on:

  43. Actinomycetes associated with marine sponge represent a promising source of bioactive compounds. Herein, we report the isolation, identification, and bioactivity evaluation of Streptomyces sp. NMF6 associated wit...

    Authors: Nayer Mohamed Fahmy and Asmaa Mohamed Abdel-Tawab
    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:102
    Content type: Research Published on:

  44. The SARS-CoV-2 belongs to Coronaviridae family infects host cells by the interaction of its spike glycoprotein and angiotensin-converting enzyme 2 (ACE 2) of host cells. Upon entry, the virus uses its RNA depe...

    Authors: Lokanathan Srikanth and Potukuchi Venkata Gurunadha Krishna Sarma
    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:101
    Content type: Short Communications Published on:

  45. Hypoxia refers to the condition of low oxygen pressure in the atmosphere and characterization of response to hypoxia as a biological complex puzzle, is challenging. Previously, we carried out a comparative gen...

    Authors: Hamed Kharrati-Koopaee, Esmaeil Ebrahimie, Mohammad Dadpasand, Ali Niazi, Rugang Tian and Ali Esmailizadeh
    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:100
    Content type: Research Published on:

  46. Soil salinity has been one of the biggest hurdles in achieving better crop yield and quality. Plant growth-promoting rhizobacteria (PGPR) are the symbiotic heterogeneous bacteria that play an important role in...

    Authors: Arti Sharma, Kamal Dev, Anuradha Sourirajan and Madhu Choudhary
    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:99
    Content type: Research Published on:

  47. Chronic lymphocytic leukemia (CLL) is the most common form of adult leukemia. This disease is genetically heterogeneous, and approximately 85% of patients with CLL harbor chromosomal aberrations that are consi...

    Authors: Ola M. Eid, Rania M. A. Abdel Kader, Lamiaa A. Fathalla, Amany H. Abdelrahman, Ahmed Rabea, Rana Mahrous and Maha M. Eid
    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:98
    Content type: Research Published on:

  48. Plant-associated microbes (endophytes) have a significant relationship to enhance plant growth and crop productivity by producing proficient bioactive metabolites. Since endophytes promoted plant growth either...

    Authors: Mustafa Elsayed Abd Elsallam, Shahira Hussainy EL-Moslamy, Ahmed Abd El-Al and Hoda Farouk Zahran
    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:97
    Content type: Research Published on:

  49. In crop plants, to cope up with the demand of food for rising population, revolutionary crop improvement programmes are being implemented for higher and higher yields. Abiotic stress, especially at flowering s...

    Authors: Sridevi Muppala, Pavan Kumar Gudlavalleti, Kodandarami Reddy Malireddy, Sateesh Kumar Puligundla and Premalatha Dasari
    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:96
    Content type: Research Published on:

  50. Drug response is below genetic influence, proven by the genetic variants. Pharmacogenetics trials are performed in many diseases, including coronary artery disease. This study was designed to determine the gen...

    Authors: Shaimaa Y. Abdulfattah and Salwa J. Al-Awadi
    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:95
    Content type: Research Published on:
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  • ISSN: 2090-5920 (electronic)