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  1. Serine/threonine kinase 3 (AKT3) is a protein-coding gene that is associated with several cattle immune diseases including different tumors and cancers. The objective of this study was to investigate the differen...

    Authors: Farmanullah Farmanullah, Mostafa Gouda, Zhang Min, Xu Sutong, Mohib Ullah KaKar, Sami Ullah Khan, Muhammad Salim, Momen Khan, Zia ur Rehman, Hira Sajjad Talpur, Faheem Ahmed Khan, Nuruliarizki Shinta Pandupuspitasari and Zhang Shujun
    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:164
  2. Pi-ta is a major blast resistant gene, introgressed from indica rice varieties. In this study, diversity of the Pi-ta gene of 47 Sri Lankan rice accessions was studied by bioinformatics, and the results were vali...

    Authors: Suvanthini Terensan, H. Nishadi S. Fernando, J. Nilanthi Silva, S. A. Chandrika N. Perera, Nisha S. Kottearachchi and O. V. D. S. Jagathpriya Weerasena
    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:163
  3. The ocean is one of the world’s most important sources of bioactive chemicals in the marine environment. Microbiologists, ecologists, agronomists, taxonomists, and evolutionary biologists have been increasingl...

    Authors: Sahar Saleh Mohamed, Sayeda Abdelrazek Abdelhamid and Radwa Hassaan Ali
    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:162
  4. Moscatilin is a bibenzyl derivative (stilbenoid), mainly found in Dendrobium species. This plant-derived chemical is a potential cytotoxic anticancer drug that acts against different cancer types. The present stu...

    Authors: Ipsita Pujari, Ritobrata Sengupta and Vidhu Sankar Babu
    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:161
  5. In silico analysis of transcription start sites, promoter regions, transcription factors and their binding sites, and CpG islands for the Trametes hirsuta strain 072 genome were performed to understand the regula...

    Authors: Dinku Senbeta and Mulugeta Kebede
    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:160
  6. Chronic kidney Failure (CKD), particularly End-Stage Renal Disease (ESRD), may be serious ill-health related to a high death rate. Uremic syndrome leads to increased oxidative stress, inflammation, and dyslipi...

    Authors: Afaf Elsaid, Omnia Samir eid, Samy B. Said and Rasha F. Zahran
    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:158
  7. It remains essential for non-alcoholic fatty liver (NAFLD) patients, to develop a sensitive and specific diagnostic model. Data regarding the use of micro (mi)RNA-34 for NAFLD diagnosis are few. Routine clinic...

    Authors: Amal A. Mohamed, Ahmed El-Demery, Eman Al-Hussain, Shroouk Mousa, Ahmed Abdel Halim, Sahar M. Mostafa, Reda S. Abdelghany, Seham M. Mahmoud, Mohammad A. Elkady, Khaled Raafat, Alshymaa A. Hassnine and Mohamed M. Omran
    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:157
  8. Penicillin G amidase/acylases from microbial sources is a unique enzyme that belongs to the N-terminal nucleophilic hydrolase structural superfamily. It catalyzes the selective hydrolysis of side chain amide/a...

    Authors: Krishika Sambyal and Rahul Vikram Singh
    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:156
  9. Difficult to express peptides are usually produced by co-expression with fusion partners. In this case, a significant mass part of the recombinant product falls on the subsequently removed fusion partner. On t...

    Authors: Murad Mollaev, Artur Zabolotskii, Neonila Gorokhovets, Elena Nikolskaya, Maria Sokol, Andrey Tsedilin, Mariia Mollaeva, Margarita Chirkina, Timofey Kuvaev, Anna Pshenichnikova and Nikita Yabbarov
    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:155
  10. Hepatitis E is a liver disease caused by the pathogen hepatitis E virus (HEV). The largest polyprotein open reading frame 1 (ORF1) contains a nonstructural Y-domain region (YDR) whose activity in HEV adaptatio...

    Authors: Zoya Shafat, Anwar Ahmed, Mohammad K. Parvez and Shama Parveen
    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:154
  11. Mastitis is one of the major diseases causing economic loss to the dairy industry by reducing the quantity and quality of milk. Thus, the objective of this scientific study was to find new biomarkers based on ...

    Authors: Farmanullah Farmanullah, Xianwei Liang, Faheem Ahmed Khan, Mohammad Salim, Zia ur Rehman, Momen Khan, Hira Sajjad Talpur, N. M. Schreurs, Mostafa Gouda, Sami Ullah Khan and Zhang Shujun
    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:153
  12. Mining for precious metals is detrimental to the composition of soil structure and microbial diversity distribution and is a health risk to human communities around the affected communities. This study was aim...

    Authors: U. B. Ibrahim, A. H. Kawo, I. Yusuf and S. Yahaya
    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:152
  13. To develop new breeding technology to improve the breeding ability of bovine, it is the development trend to find the main reason for the occurrence of atresia in these organisms. Transcriptomes of small (100–...

    Authors: Khairy Mohamed Zoheir, Ahmed Mohamed Darwish, Yang Liguo and Abdelkader E. Ashour
    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:151
  14. Impact of interleukin 28B (IL28B) rs12979860 polymorphism on response to direct-acting antivirals agents in HCV genotype 4-infected patients is under investigation. Zinc may have an advantage in improvement of li...

    Authors: Abdelfattah M. Attallah, Dalia Omran, Mohamed A. Abdelrazek, Mohamed Hassany, Sameh Saif, Aza Farid, Riham El Essawey, Muhammad Abdel Ghaffar, Marwa Aabdelghany and Ayman Yosry
    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:150
  15. Soil pollution by heavy metals increases the bioavailability of metals like hexavalent chromium (Cr (VI)), subsequently limiting plant growth and reducing the efficiency of phytoremediation. Plant growth-promo...

    Authors: Nabil Tirry, Aziza Kouchou, Bouchra El Omari, Mohamed Ferioun and Naïma El Ghachtouli
    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:149
  16. Metabolic syndrome is defined as a group of interrelated biochemical, clinical, and metabolic factors that directly increase the risk of cardiovascular disease, obesity, and type 2 diabetes mellitus. MicroRNA-...

    Authors: Miral M. Refeat, Naglaa Abu-Mandil Hassan, Inass Hassan Ahmad, Eman Roshdy Mohamed Mostafa and Khalda S. Amr
    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:147
  17. Chromobacterium species, through their bioactive molecules, help in combating biotic and abiotic stresses in plants and humans. The present study was aimed to identify, characterize and preserve in natural gums t...

    Authors: Sushil K. Sharma, Rakhi Dhyani, Ees Ahmad, Pankaj K. Maurya, Madhu Yadav, Ramesh Chandra Yadav, Vinod Kumar Yadav, Pawan K. Sharma, Mahaveer P. Sharma, Aketi Ramesh and Anil K. Saxena
    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:146
  18. Potato (Solanum tuberosum L.) is one of the most important food crops in the world. Pathogens remain as one of the major constraints limiting potato productivity. Thus, understanding of gene regulation mechanism ...

    Authors: Atnafu Kebede and Mulugeta Kebede
    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:145
  19. Rosa damascena Mill is a well-known species of the rose family. It is famous for its essential oil content. The aim of the present study was to assess the genetic diversity and population structure of a mini core...

    Authors: Atefeh Sadat Mostafavi, Mansour Omidi, Reza Azizinezhad, Alireza Etminan and Hassanali Naghdi Badi
    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:144
  20. Hydrolysis of cellulose-based biomass by cellulases produce fermented sugar for making biofuels, such as bioethanol. Cellulases hydrolyze the β-1,4-glycosidic linkage of cellulose and can be obtained from cult...

    Authors: Rahmat Eko Sanjaya, Kartika Dwi Asni Putri, Anita Kurniati, Ali Rohman and Ni Nyoman Tri Puspaningsih
    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:143
  21. Mung bean is a pulse crop principally grown in the tropic and subtropic parts of the world for its nutrient-rich seeds. Seven mung beans accessions from Eastern Kenya were evaluated using thirteen phenotypic t...

    Authors: Jedidah Wangari Mwangi, Oduor Richard Okoth, Muchemi Peterson Kariuki and Ngugi Mathew Piero
    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:142
  22. Livin/BIRC7 is a member of the inhibitors of apoptosis proteins family which are implicated in development of cancer through the inhibition of apoptosis process. This case-control study was intended to investigat...

    Authors: Basma K. Elmekkawy, Rasha M. S. Shoaib, Amal K. Seleem, Dalia Shaalan and Entsar A. Saad
    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:141

    The Correction to this article has been published in Journal of Genetic Engineering and Biotechnology 2022 20:27

  23. Bacterial biofilms are aggregation or collection of different bacterial cells which are covered by self-produced extracellular matrix and are attached to a substratum. Generally, under stress or in unfavorable...

    Authors: Shivani Singh, Saptashwa Datta, Kannan Badri Narayanan and K. Narayanan Rajnish
    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:140
  24. Cardiovascular disease (CVD) remains the major cause of death worldwide. Most CVD can be prevented by addressing risk factors. Acute myocardial infarction (AMI) is an inflammatory disorder characterized by cha...

    Authors: Ingy M. Hashad, Habiba Nosseir, Gamal M. Shaban, Mohamed F. Abdel Rahman and Mohamed Z. Gad
    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:139
  25. As the body of scientific research focusing on the severe acute respiratory syndrome coronavirus 2 or SARS-CoV-2 continues to grow, several mutations have been reported as very common across the globe. In this...

    Authors: Syeda Tasnim Quayum and Saam Hasan
    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:138
  26. This work investigates the production of citric acid from cashew apple juice, an abundant waste in the processing of cashew, using a local strain of Aspergillus niger and the application of the citric acid as a c...

    Authors: Adekunle Olusegun Adeoye and Agbaje Lateef
    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:137
  27. The present study reports metagenomic sequencing and microbial diversity analysis of the sediment samples of a semi-intensive penaeid shrimp culture system. 16S rRNA gene-based high-throughput sequencing revea...

    Authors: M. S. Chithira, P. V. Aishwarya, Anjali S. Mohan and Swapna P. Antony
    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:136
  28. Protoplasts (i.e., naked plant cells) can be used for in vitro manipulations and genetic improvement in cultivars with economic value. During the last decade, protoplast research in economic brown algae has be...

    Authors: Jose Avila-Peltroche, Boo Yeon Won and Tae Oh Cho
    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:135
  29. The recent recovery of Gyrinops walla as a potential producer of market-quality agarwood in mature damaged woods and branches has led to the intense illicit felling and exportation of G. walla leading to the verg...

    Authors: Sachithri Munasinghe, Seneviratnege Somaratne, Shyama Weerakoon and Chandani Ranasinghe
    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:134
  30. Amoebiasis, being endemic worldwide, is the second leading cause of parasite-associated morbidity and mortality after malaria. The human parasite Entamoeba histolytica is responsible for the disease. Metronidazol...

    Authors: Suchetana Pal, Pinaki Biswas, Raktim Ghosh and Somasri Dam
    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:133
  31. Vitiligo is a common pigmentary disorder in which autoimmunity has been suggested to play an important role. Toll-like receptor (TLR) family are recognized different molecular structures expressed on immune ce...

    Authors: Maha Abdelsalam, Sherihan H. Allam, Marwa Zohdy, Hend Magdy and Maged Mostafa
    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:132
  32. The aim of this work was to synthesize copper oxide nanoparticles (CuO NPs) utilizing heartwood aqueous extract of Suaeda maritima (L.) Dumort. The synthesis of CuO NPs using green methodology with small size and...

    Authors: Pavani Peddi, Prasada Rao PTSRK, Nannapaneni Usha Rani and S. Lakshmi Tulasi
    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:131
  33. In resource-limited countries, ABO, HLA, MNS, Kells, and hemoglobin electrophoresis are classic tests for the resolution of paternity disputes due to their affordable cost. The limitations of these tests in ca...

    Authors: Missa Millogo, Serge Theophile Soubeiga, Bapio Valerie Jean Telesphore Bazie, Theodora Mahoukede Zohoncon, Abdoul Karim Ouattara, Albert Theophane Yonli and Jacques Simpore
    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:130
  34. DNA markers improved the productivity and accuracy of classical plant breeding by means of marker-assisted selection (MAS). The enormous number of quantitative trait loci (QTLs) mapping read for different plan...

    Authors: Nazarul Hasan, Sana Choudhary, Neha Naaz, Nidhi Sharma and Rafiul Amin Laskar
    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:128
  35. Tuta absoluta Meyrick 1917 (Lepidoptera: Gelechiidae) is an invasive, pesticide resistant, and a major treat of tomato production in the world. It needs effective management options that naturally infect the inse...

    Authors: Birhan Aynalem, Diriba Muleta, Juan Venegas and Fassil Assefa
    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:127
  36. Nanoparticle synthesis is a very interesting area of research currently due to the wide applications of nanoparticles. The nanoparticles have a diameter ranging between 1 and 100 nm and they are used in differ...

    Authors: Deeksha Chugh, V. S. Viswamalya and Bannhi Das
    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:126
  37. Genome of an organism has always fascinated life scientists. With the discovery of restriction endonucleases, scientists were able to make targeted manipulations (knockouts) in any gene sequence of any organis...

    Authors: Anuradha Bhardwaj and Vikrant Nain
    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:125
  38. Phospholipases hydrolyze glycerophospholipids and generate diverse lipid-derived molecules with secondary messenger activity. Out of these, phospholipase C (PLC) specifically cleaves the phospholipids at ester...

    Authors: Madhvi Kanchan, Thakku R. Ramkumar, Himani and Jaspreet K. Sembi
    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:124
  39. γ-Aminobutyric acid sub-type A receptors (GABAARs) are the most prominent inhibitory neurotransmitter receptors in the CNS. They are a family of ligand-gated ion channel with significant physiological and therape...

    Authors: Amr Ghit, Dina Assal, Ahmed S. Al-Shami and Diaa Eldin E. Hussein
    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:123
  40. Terrestrial orchids belonging to the Orchis genus are difficult to propagate and are under great pressure in their natural habitats. Studies regarding the influence of photoperiod and temperature regimes on Orchi...

    Authors: Aleksandra Yurievna Nabieva
    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:122
  41. Canine circovirus is a deadly pathogen of dogs and causes vasculitis and hemorrhagic enteritis. It causes lethal gastroenteritis in pigs, fox, and dogs. Canine circovirus genome contains two main (and opposite) t...

    Authors: Pankaj Jain, Amit Joshi, Nahid Akhtar, Sunil Krishnan and Vikas Kaushik
    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:121
  42. The present study dealt with the screening of soil bacteria with antibacterial activity from different locations in Bangalore, India. Antibiotics play the role of self-defense mechanism for the bacteria and ar...

    Authors: R. Prashanthi, Shreevatsa G.K., Krupalini S. and Manoj L.
    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:120
  43. Sandwich ELISA is an ideal antigen detection and quantification assay. Recently, it was used as the basic concept for high technology diagnostics. The specificity of the assay depends on the exclusion of detec...

    Authors: Rola Nadeem, Ahmed B. Barakat and Mahmoud M. Bahgat
    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:119
  44. Illicium griffithii is an aromatic medicinal tree species that has been listed in the IUCN Red List as an endangered species. Dried seed pods of I. griffithii have a good market potential in the spices and pharma...

    Authors: Rajib Borah, Atanu Bhattacharjee, Satyawada Rama Rao, Vineet Kumar, Pradeep Sharma, Krishna Upadhaya and Hiranjit Choudhury
    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:118
  45. Oleuropein, the main bitter phenolic glucoside responsible for green olive bitterness, may be degraded by the β-glucosidase enzyme to release glucose and phenolic compounds.

    Authors: Yahya Rokni, Houssam Abouloifa, Reda Bellaouchi, Ismail Hasnaoui, Sara Gaamouche, Zahra Lamzira, Riadh B. E. N. Salah, Ennouamane Saalaoui, Nabil Ghabbour and Abdeslam Asehraou
    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:117
  46. Ovarian cancer causes more deaths than any other cancer of the female reproductive system because there is no effective screening and most women are diagnosed at advanced stages. The probability of survival at...

    Authors: J. N. Nikhitha, K. S. Swathy and R. Pratap Chandran
    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:116
  47. Vitamin D receptor (VDR) is known as one of the cellular regulators for several metabolic pathways indicating its pivotal role in the pathological pathway of numerous diseases. Considering the high frequency o...

    Authors: Nayera E. Hassan, Sahar A. El-Masry, Waheba Ahmed Zarouk, Ghada Nour Eldeen, Rehab M. Mosaad, Mahmoud A. S. Afify, Manal M. Aly and Aya Khalil
    Citation: Journal of Genetic Engineering and Biotechnology 2021 19:115

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