Table 1 The candidate SARS-CoV-2 epitopes for the Egyptian most frequent alleles of MHC class I molecules
From: Immunoinformatics approach of epitope prediction for SARS-CoV-2
Serial in Supplementary Table 1 | Position | HLA haplotype | Epitope sequence | 4PRP | 5YXN | Antigenicity response | Score | Protein | HLA crystal structure |
|---|---|---|---|---|---|---|---|---|---|
12 | 214 | HLA-B*35:01, HLA-A*02:01 | RDLPQGFSA | − 255.9 | − 185.69 | 0.8947 | 0.286485 | Spike | 4PRP, 5YXN |
28 | 269 | HLA-B*35:01, HLA-A*02:01 | YLQPRTFLL | − 236.05 | − 224.82 | 0.4532 | 0.972695 | Spike | 4PRP, 5YXN |
25 | 691 | HLA-A*02:01 | SIIAYTMSL | − 230.22 | − 220.73 | 0.5234 | 0.575949 | Spike | 5YXN |
7 | 2209 | HLA-A*02:01 | FCLEASFNY | − 314.45 | − 191.75 | 1.5042 | 0.411451 | ORF1ab | 5YXN |
79 | 103 | HLA-B*35:01, HLA-A*02:01 | TLGVLVPHV | − 295.42 | − 211.69 | 0.5583 | 0.713924 | ORF1ab | 4PRP, 5YXN |
241 | 3050 | HLA-B*35:01 | GEYSHVVAF | − 293.81 | − 213.74 | 0.6428 | 0.523635 | ORF1ab | 4PRP |
14 | 487 | HLA-B*35:01 | NCYFPLQSY | − 225 | − 183.06 | 0.8743 | 0.558006 | Spike | 4PRP |