Table 7 AllergenFP score and proteins considered for Tropheryma whipplei
From: Codon usage studies and epitope-based peptide vaccine prediction against Tropheryma whipplei
Proteins/no. of amino acid residues | GenBank-accession no. | Function | Allergen FP score | Inference |
|---|---|---|---|---|
Prolipoprotein diacylglyceryl transferase (Tropheryma whipplei) 272 aa protein | WP_042506957.1 | Catalyzes the transition of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the development of mature lipoproteins | 0.87 | Non-allergen |
Excinuclease ABC subunit UvrC (Tropheryma whipplei) 607 aa protein | WP_042506954.1 | DNA excision repair | 0.82 | Non-allergen |
Holliday junction resolvase RuvX (Tropheryma whipplei) 145 aa protein | WP_042506082.1 | Nuclease activity, rRNA processing | 0.82 | Non-allergen |
Exodeoxyribonuclease VII large subunit (Tropheryma whipplei) 404 aa protein | WP_042506175.1 | Degrades single-stranded DNA bidirectionally, first into massive acid-insoluble oligonucleotides, then into small acid-soluble oligonucleotides | 0.82 | Non-allergen |
Isoprenyl transferase (Tropheryma whipplei) 249 aa protein | WP_042506056.1 | Isopentenyl diphosphate (IPP) condensation with allylic pyrophosphates is catalyzed, resulting in a number of terpenoids. | 0.80 | Non-allergen |
3-oxoacyl-ACP reductase FabG (Tropheryma whipplei) 238 aa protein | WP_011096407.1 | Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis | 0.82 | Non-allergen |
ABC transporter permease subunit (Tropheryma whipplei) 332 aa protein | WP_206536426.1 | Transmembrane transportation of molecules | 0.90 | Non-allergen |