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Table 7 AllergenFP score and proteins considered for Tropheryma whipplei

From: Codon usage studies and epitope-based peptide vaccine prediction against Tropheryma whipplei

Proteins/no. of amino acid residues GenBank-accession no. Function Allergen FP score Inference
Prolipoprotein diacylglyceryl transferase (Tropheryma whipplei)
272 aa protein
WP_042506957.1 Catalyzes the transition of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the development of mature lipoproteins 0.87 Non-allergen
Excinuclease ABC subunit UvrC (Tropheryma whipplei)
607 aa protein
WP_042506954.1 DNA excision repair 0.82 Non-allergen
Holliday junction resolvase RuvX (Tropheryma whipplei)
145 aa protein
WP_042506082.1 Nuclease activity, rRNA processing 0.82 Non-allergen
Exodeoxyribonuclease VII large subunit (Tropheryma whipplei)
404 aa protein
WP_042506175.1 Degrades single-stranded DNA bidirectionally, first into massive acid-insoluble oligonucleotides, then into small acid-soluble oligonucleotides 0.82 Non-allergen
Isoprenyl transferase (Tropheryma whipplei)
249 aa protein
WP_042506056.1 Isopentenyl diphosphate (IPP) condensation with allylic pyrophosphates is catalyzed, resulting in a number of terpenoids. 0.80 Non-allergen
3-oxoacyl-ACP reductase FabG (Tropheryma whipplei)
238 aa protein
WP_011096407.1 Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis 0.82 Non-allergen
ABC transporter permease subunit (Tropheryma whipplei)
332 aa protein
WP_206536426.1 Transmembrane transportation of molecules 0.90 Non-allergen