Immunoinformatics-aided rational design of multiepitope-based peptide vaccine (MEBV) targeting human parainfluenza virus 3 (HPIV-3) stable proteins

Journal of Genetic Engineering and Biotechnology

Table 2 The pivotal properties of matrix protein epitopes for vaccine development

Epitopes	Antigenicity	Allergenicity	Toxicity	Human homology	IFN-δ	IL-4	IL-10
MHC-I
LPLDRSIKF	Antigen	Non-allergen	Non-toxic	Non-homolog	Non-inducer	Inducer	Non-inducer
SENGHIEPL	Antigen	Non-allergen	Non-toxic	Non-homolog	Inducer	Inducer	Non-inducer
GSLPIGLAK	Antigen	Non-allergen	Non-toxic	Non-homolog	Inducer	Inducer	Non-inducer
MHC-II
VFLLGFFEMERIKDK	Antigen	Non-allergen	Non-toxic	Non-homolog	Inducer	Inducer	Inducer
GEFRYYPNIIAKGVG	Antigen	Non-allergen	Non-toxic	Non-homolog	Non-inducer	Inducer	Non-inducer
PSLPGEFRYYPNIIA	Antigen	Non-allergen	Non-toxic	Non-homolog	Inducer	Inducer	Non-inducer
EFRYYPNIIAKGVGK	Antigen	Non-allergen	Non-toxic	Non-homolog	Non-inducer	Inducer	Non-inducer