Table 2 S. xylosus NM36 genome analysis for antibiotics resistance. The annotation was based on the protein domain database [38,39,40,41]

1.

JARUHN010000001.1

83,305

84,474

 + 

1170

Multidrug resistance protein B-efflux pumps. MFS family multiresistance [17, 46]

2.

JARUHN010000001.1

223,144

224,019

 + 

876

LytH protein, involved in methicillin resistance/N-acetylmuramoyl-L-alanine amidase (EC 3.5.1.28) domain [23]

3.

JARUHN010000002.1

27,376

25,487

-

1890

Membrane component of multidrug resistance system—conserved domains: drug resistance transporter, EmrB/QacA subfamily; SmvA family efflux MFS transporter [17]

4.

JARUHN010000002.1

28,165

28,713

 + 

549

TetR family regulatory protein of MDR cluster. Multidrug resistance, 2-protein version found in gram-positive bacteria [38]

5.

JARUHN010000002.1

65,241

65,846

 + 

606

Transcriptional regulator, TetR family

6.

JARUHN010000002.1

137,322

136,774

-

549

7.

JARUHN010000004.1

102,889

103,473

 + 

585

8.

JARUHN010000005.1

115,390

114,833

-

558

9.

JARUHN010000024.1

3420

3983

 + 

564

TetR family regulatory protein

10.

JARUHN010000027.1

12,167

12,718

 + 

552

11.

JARUHN010000002.1

30,005

28,797

-

1209

Teicoplanin resistance, associated membrane protein TcaB [10]

12.

JARUHN010000002.1

31,832

30,447

-

1386

Teicoplanin resistance, associated membrane protein TcaA [10]

13.

JARUHN010000002.1

32,591

32,127

-

465

Teicoplanin resistance, associated HTH-type transcriptional regulator TcaR, teicoplanin resistance in Staphylococcus [10]

14.

JARUHN010000002.1

111,486

112,688

 + 

1203

Bicyclomycin resistance protein, TcaB2 [10]

15.

JARUHN010000002.1

142,698

141,520

-

1179

Chloramphenicol resistance protein

16.

JARUHN010000003.1

100,532

101,692

 + 

1161

Quinolone resistance protein, norA [18]

17.

JARUHN010000006.1

57,874

54,734

-

3141

RND multidrug efflux transporter; Acriflavin resistance protein [44]

18.

JARUHN010000007.1

27,204

28,379

 + 

1176

FmtA protein, involved in methicillin resistance [65]

19.

JARUHN010000008.1

5175

4807

-

369

FemC, factor involved in methicillin resistance/glutamine synthetase repressor [26]

20.

JARUHN010000008.1

106,860

106,627

-

234

Acyl carrier protein/HmrB protein involved in methicillin resistance [30]

21.

JARUHN010000012.1

19,897

21,081

 + 

1185

HmrA protein, involved in methicillin resistance/amidohydrolase of M40 family [30]

22.

JARUHN010000022.1

24,055

26,580

 + 

2526

FmtC (MrpF) protein, involved in methicillin resistance/L-lysine modification of phosphatidylglycerol [65]

23.

JARUHN010000036.1

2573

2992

 + 

420

Fosfomycin resistance protein, FosB-BlaZ family, FosB [58]