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Journal of Genetic Engineering and Biotechnology
Fig. 7 | Journal of Genetic Engineering and Biotechnology

Fig. 7

From: Acetaminophen-traces bioremediation with novel phenotypically and genotypically characterized 2 Streptomyces strains using chemo-informatics, in vivo, and in vitro experiments for cytotoxicity and biological activity

Fig. 7

Photo-micrographs of mice liver sections stained by H&E from A normal control group 1, demonstrated normal histological structure of organized hepatocytes and lobules (black arrow) (100 ×). B DMSO negative control group 2, showed hepatocyte parenchymal features comparable to the normal control (A) (200 ×). C Mice treated with acetaminophen/paracetamol as positive control group 3, showing mid-zonal coagulative necrosis of hepatocytes and hyperplasia of Kupffer cells, leukocytic infiltration with intracellular fat droplets arrow (100 ×). D mice treated with M33 extract 1b group 4, showed no inflammatory cell infiltrates (100 ×). E Mice group treated with M33 extract 1a group 5, demonstrated the normal histological structure of hepatic lobules with mild hepatic sinusoid dilatation (200 ×) [100 × or 200 × magnification]

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