Skip to main content

Table 1 Genome annotation pipelines

From: Recent advances in genome annotation and synthetic biology for the development of microbial chassis

Pipeline name

Details

Source

URL

PGAP

An automatic prokaryotic genome annotation pipeline, which is a set of computational tools and algorithms that are used to predict the presence and location of genes in the genome of a prokaryotic organism

 [63]

https://www.ncbi.nlm.nih.gov/genome/annotation_prok/

Prokka v1.14.6

A software tool for rapidly annotating genomes, which uses external feature prediction tools like RNAmmer and Prodigal to identify the coordinates of genomic features within contigs

[61]

https://github.com/tseemann/prokka

RAST

A fully automated pipeline for annotating bacterial and archaeal genomes

[10]

https://rast.nmpdr.org/

MicrobeAnnotator

A tool that predicts all types of prokaryotic genes from a single or a set of anonymous genomic sequences of varying lengths. This tool is commonly used in the analysis of prokaryotic genomes

[58]

https://github.com/cruizperez/MicrobeAnnotator

EggNOG-mapper v2.1.9

A tool for automatically annotating the function of genes based on precomputed orthology assignments

[13]

http://eggnog-mapper.embl.de/

DRAM

A tool that uses databases like KEGG and PFAM to organize microbial genomic information into a catalog of microbial traits

[62]

https://github.com/WrightonLabCSU/DRAM

DFAST

A pipeline that supports genome submission to the public database DNA Data Bank of Japan (DDBJ) using the GHOSTX algorithm

[67]

https://dfast.ddbj.nig.ac.jp/

GenSAS

An online pipeline that provides structural and functional annotations of genomic sequences

[28]

https://www.gensas.org/

BlastKOALA

A tool that carries out automated annotation of fully sequenced genomes by using KEGG's internal annotation tool, KOALA, to assign K numbers to KEGG genes using SSEARCH computation

[33]

https://www.kegg.jp/blastkoala/