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Table 2 Effect of C. equisetifolia extract incorporated with gold nanoparticles (Au-NPs) against toxicity induced by chlorpyrifos (CPF) on the biochemical measurements related to the integrity of liver and brain tissues of rats

From: The hepato- and neuroprotective effect of gold Casuarina equisetifolia bark nano-extract against Chlorpyrifos-induced toxicity in rats

 

C

Au-C. equisetifolia nano-extract

CPF

CPF + Au-C. equisetifolia nano-extract

Pre-treated

Post-treated

Liver

 TNF-α (pg/g tissue)

344.00 ± 0.95

343.20 ± 0.58

726.40 ± 1.50a

427.40 ± 1.03ab

591.60 ± 1.17ab

 IL-6 (pg/g tissue)

415.40 ± 1.29

415.60 ± 1.50

877.17 ± 1.67a

516.11 ± 1.66ab

714.40 ± 2.12ab

 Hydroxyproline (kg/mg tissue)

0.32 ± 0.00

0.33 ± 0.01

0.68 ± 0.01a

0.40 ± 0.01ab

0.55 ± 0.01ab

 AChE (ng/g tissue)

0.50 ± 0.02

0.48 ± 0.02

0.31 ± 0.02a

0.30 ± 0.02a

0.29 ± 0.02a

Brain

 TNF-α (pg/g tissue)

133.00 ± 0.55

134.00 ± 0.63

280.86 ± 1.65a

165.26 ± 1.27ab

228.73 ± 1.06ab

 IL-6 (pg/g tissue)

224.80 ± 1.32

225.60 ± 0.60

474.68 ± 2.21a

279.30 ± 1.73ab

386.61 ± 2.37ab

 β-Amyloid (pg/g tissue)

6.19 ± 0.01

6.19 ± 0.01

13.08 ± 0.04a

7.69 ± 0.03ab

10.65 ± 0.01ab

 AChE (ng/g tissue)

9.37 ± 0.45

10.93 ± 0.79

7.63 ± 0.46a

10.76 ± 0.44b

9.60 ± 0.35b

  1. Data were calculated from five replicates and expressed as mean ± SE
  2. aSignificant versus control group at P ≤ 0.05
  3. bSignificant versus toxic (CPF) group at P ≤ 0.05