Journal of Genetic Engineering and Biotechnology

Table 3 In vitro screening of the antiproliferative activities of tested extracts against different carcinoma cell lines

From: Targeting apoptotic anticancer response with natural glucosinolates from cell suspension culture of Lepidium sativum

Extracts	Cytotoxicity % at 100 ug/ml
Extracts	A-375	MCF-7	HCT-116	PC3	A-549	caco2	HepG 2	BJ-1
GR	0.0 ± 0.03	0.0 ± 0.1	8.2 ± 0.7	2.0 ± 0.3	19.2 ± 0.7	25.5 ± 0.5	38.9 ± 0.8	0.0 ± 0.2
GRM	0.0 ± 0.01	6.0 ± 0.3	0.0 ± 0.4	7.8 ± 0.6	17.5 ± 0.4	20.1 ± 0.7	46.3 ± 1.3	0.0 ± 0.04
GRT	0.0 ± 0.02	0.0 ± 0.2	0.0 ± 0.2	73.9 ± 1.3	58.9 ± 1.4	58.0 ± 1.4	89.4 ± 1.1	0.0 ± 0.1
GL	18.9 ± 0.7	18.3 ± 0.4	18.5 ± 0.4	83.4 ± 0.9	71.7 ± 1.5	74.2 ± 0.9	94.4 ± 1.4	9.5 ± 0.4
GLM	25.8 ± 0.5	44.8 ± 0.7	33.5 ± 1.2	92.6 ± 2.2	59.4 ± 2.2	87.9 ± 2.1	98.2 ± 2.1	23.3 ± 0.3
GLT	0.0 ± 0.02	58.6 ± 1.1	0.0 ± 0.3	86.8 ± 0.9	35.2 ± 0.7	80.9 ± 2.1	99.8 ± 0.7	0..0 ± 0.1
OR	8.8 ± 0.6	96.6 ± 2.1	49.3 ± 0.6	97.2 ± 1.1	97.2 ± 1.4	79.3 ± 0.7	71.1 ± 2.3	68.2 ± 1.4
OL	0.0 ± 0.4	77.5 ± 1.7	46.7 ± 1.4	91.2 ± 1.7	94.6 ± 2.4	92.0 ± 1.5	60.3 ± 2.4	98.0 ± 2.3
Doxorubicin	99.9 ± 2.1	88.7 ± 1.9	72.0 ± 2.4	84.4 ± 1.8	70.0 ± 1.7	99.0 ± 2.6	90.0 ± 2.7	89.1 ± 2.2

Values = average ± standard deviation for the tested extracts; GR glucosinolates of root cell suspension, GRM glucosinolates of root cell suspension treated with L-methionine, GRT glucosinolates of root cell suspension treated with L-tyrosine, GL glucosinolates of leaf cell suspension, GLM glucosinolates of leaf cell suspension treated with L-methionine, GLT glucosinolates of leaf cell suspension treated with L-tyrosine, OR petroleum ether extract of root cell suspension, OL petroleum ether extract of leaf cell suspension

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