An immunoinformatics approach to epitope-based vaccine design against PspA in Streptococcus pneumoniae

Journal of Genetic Engineering and Biotechnology

Table 2 Predicted three HTL with their antigenic score and allergenic and toxic properties

Epitopes	Interacting alleles	Antigenicity	Allergenicity	Toxicity	IFN-γ (score)
TWYYLEASGAMKASQ	HLA-DQA105:01/DQB103:01, HLA-DQA101:02/DQB106:02, HLA-DRB107:01, HLA-DRB113:02, HLA-DRB101:01, HLA-DRB501:01, HLA-DRB104:05, HLA-DRB111:01, HLA-DRB109:01, HLA-DRB104:01, HLA-DRB3*01:01	0.7340	Negative	Negative	Positive 0.69662678
SWYYLNANGAMATGW	HLA-DRB302:02, HLA-DQA101:02/DQB106:02, HLA-DRB113:02, HLA-DQA105:01/DQB103:01, HLA-DRB501:01, HLA-DRB101:01, HLA-DRB111:01, HLA-DRB104:05, HLA-DRB104:01, HLA-DRB109:01, HLA-DRB301:01, HLA-DRB107:01	0.6068	Negative	Negative	Positive 1.3611371
GSWYYLNANGAMATG	HLA-DRB113:02, HLA-DQA101:02/DQB106:02, HLA-DQA105:01/DQB103:01, HLA-DRB104:05, HLA-DRB501:01, HLA-DRB115:01, HLA-DRB101:01, HLA-DRB111:01, HLA-DRB302:02, HLA-DRB104:01, HLA-DRB109:01, HLA-DRB301:01, HLA-DRB1*07:01	0.6041	Negative	Negative	Positive 0.29956413