Table 2 Hypothetical proteins with confidently predicted function (= 3 software prediction) and subcellular localization
From: In silico structural and functional characterization of hypothetical proteins from Monkeypox virus
S.NO | Protein name | UniprotKB identifier | Function | Virus-PLoc prediction |
|---|---|---|---|---|
1 | Hypothetical protein MPXVgp016 | Q8V563 | Inhibitor of host NF-kappa-B activation | Endoplasmic reticulum |
2 | Hypothetical protein MPXVgp026 | Q8V554 | Immunosuppressive activities | Endoplasmic reticulum |
3 | Hypothetical protein MPXVgp056 | Q8V524 | Virion assembly | Cytoplasm |
4 | Hypothetical protein MPXVgp066 | Q8V514 | Membrane protein | Endoplasmic reticulum |
5 | Hypothetical protein MPXVgp067 | Q8V513 | Binds to the hairpin form of the viral telomeric sequence | Plasma membrane |
6 | Hypothetical protein MPXVgp074 | Q8V506 | Nuclease | Inner layer |
7 | Hypothetical protein MPXVgp147 | Q8V4U2 | Virulence | Outer capsid |
8 | Hypothetical protein MPXVgp185 | Q8V4Q4 | Prevent host NF-kappa-B activation | Cytoplasm |