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Journal of Genetic Engineering and Biotechnology

Table 1 The top 10 hub genes and their degree of interactions in the network

From: Computer-aided analysis of quercetin mechanism of overcoming docetaxel resistance in docetaxel-resistant prostate cancer

Rank

Gene symbol

Degree of interactions

1.

EGFR

102

2.

SRC

95

3.

VEGFA

81

4.

CD44

58

5.

BRCA1

52

6.

STAT1

50

7.

PPARG

46

8.

GSK3B

41

9.

CDK1

40

10.

SMAD4

40

  1. EGFR Epidermal growth factor receptor, SRC Proto-oncogene tyrosine-protein kinase Src, VEGFA Vascular endothelial growth factor A, CD44 CD44 antigen, BRCA1 Breast cancer type 1 susceptibility protein, STAT1 Signal transducer and activator of transcription 1, PPARG Peroxisome proliferator-activated receptor gamma, GSK3B Glycogen synthase kinase-3 beta, CDK1 Cyclin-dependent kinase 1, SMAD4 Mothers against decapentaplegic homolog 4
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