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Journal of Genetic Engineering and Biotechnology

Table 2 Effect of T. viride l-asparaginase on liver function enzymes in serum of control and DENA-intoxicated

From: Therapeutic impact of purified Trichoderma viride l-asparaginase in murine model of liver cancer and in vitro Hep-G2 cell line

Parameter

Groups

Normal control

(1)

Normal-treated enzyme

(2)

(+ ve) DENA

(3)

DENA-treated enzyme

(4)

AST (U/mL)

116.2 ± 4.5a

117.5 ± 17.6a

173.83 ± 23.1b

117.5 ± 10.7a

ALT (U/mL)

55.2 ± 3.3a

54.7 ± 3.83a

81.33 ± 13.53b

61.33 ± 6.74a

ALP (U/L)

129.7 ± 4.1a

141.85 ± 35.7b

207.1 ± 7.5c

116.18 ± 12.8a

T. bilirubin (mg/dL)

1.34 ± 0.16a

1.48 ± 0.21a

1.69 ± 0.16b

1.53 ± 0.18a

  1. Data are expressed as means ± SD of six mice in each group
  2. Analysis of data is carried out by one-way (ANOVA) (analysis of variance) accompanied by post hoc (LSD, least significant difference) (CoStat, computer program)
  3. Different letters indicate that these groups are significantly correlated at P > 0.05
  4. Different letters are significantly different from each other while similar letters are not significantly different at P < 0.05
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