Fig. 2

Kidney section from a control rat group showed normal histology kidney cells before (A) and after (B) l-asparaginase treatment (non-significant change with respect to control); b treated rat (C&C*) given diethyl nitrosamine DENA (chemotoxic agent) showed the appearance of the corpuscles with high cellularity and obliterated capsular space, proximal convoluted tubules with destructed epithelial lining of distal convoluted tubules, shrunken glomeruli indicating degeneration of nuclei and increased Bowman’s space; c treated l-asparaginase (D&D*) showed a reduction of congestion of the blood vessels, the renal cortex of the renal corpuscle with nearly normal glomerulus which restored shrunken glomeruli and Bowman’s space