Non-diarrhoeal | Diarrhoel rats (1 mL of magnesium sulphate) | |||||
---|---|---|---|---|---|---|
Normal saline | Normal saline | Loperamide | Q3G-RF from S. mombin leaves (mg/kg body weight) | |||
1 mL | 1 mL | 3 mg/kg body weight | 100 | 200 | 400 | |
Onset time (minutes) | 50.67 ± 1.04 | 55.98 ± 1.04b | 120.55 ± 1.15# | 74.65 ± 1.07# | 120.59 ± 1.19# | > longest time the experiment lasted |
Total number of faeces | 1.00 ± 1.01 | 6.60 ± 1.02b | 2.00± 0.05# | 3.00 ± 0.07# | 2.60 ± 0.06# | 1.90 ± 0.01# |
Number of wet faeces | 0.10 ± 0.02 | 4.40 ± 0.03b | 0.60 ± 0.03# | 1.50 ± 0.02# | 0.60 ± 0.04# | - |
Fresh weight of faeces (g) | 0.15 ± 0.10 | 3.98 ± 0.07b | 0.55 ± 0.01# | 0.90 ± 0.02# | 0.67 ± 0.95# | - |
Water content of aces (mL | 0.01 ± 0.00 | 1.59 ± 0.01b | 0.33 ± 0.04# | 0.99 ± 0.08# | 0.47 ± 0.11# | - |
Inhibition of defecation (%) | - | 0 | 85 | 64 | 86 | 100 |