Non-diarrhoeal | Diarrhoel rats (1 mL of castor oil) | |||||
---|---|---|---|---|---|---|
Normal saline | Normal saline | Loperamide | Q3G-RF from S. mombin leaves (mg/kg body weight) | |||
1 mL | 1 mL | 3 mg/kg body weight | 100 | 200 | 400 | |
Onset time (minutes) | 54.45 ± 1.01 | 58.15 ± 1.05b | 121.78 ± 1.80# | 75.68 ± 1.17# | 92.19 ± 1.19# | 128.77 ± 1.82# |
Total number of faeces | 1.10 ± 0.11 | 5.80 ± 0.15b | 2.00± 0.12# | 3.90 ± 0.17# | 2.80 ± 0.16# | 2.00 ± 1.10# |
Number of wet faeces | 0.10 ± 0.03 | 5.10 ± 0.13b | 0.70 ± 0.03# | 1.60 ± 0.02# | 0.90 ± 0.04# | 0.70 ± 0.02# |
Fresh weight of faeces (g) | 0.19 ± 0.10 | 3.59 ± 0.11b | 0.51 ± 0.07# | 2.11 ± 0.10# | 0.90 ± 0.05# | 0.58 ± 0.05# |
Water content of faeces (mL) | 0.02 ± 0.00 | 1.88 ± 0.01b | 0.41 ± 0.04# | 1.01 ± 0.08# | 0.67 ± 0.11# | 0.45 ± 0.03# |
Inhibition of defecation (%) | - | 0 | 85 | 67 | 80 | 86 |