Fig. 1

In vivo antibacterial activity of Q3G-RF from S. mombin leaves on S. flexneri-induced diarrhoea over 14 days of treatment. Number of Shigella flexneri in stool (A) and variation of the relative body weight (B) of male Wistar rats treated with normal saline, inoculum (2 mL) + normal saline (1 mL), inoculum (2 mL) + ciprofloxacin (2.5 mg/kg body weight), inoculum (2 mL) + Q3G-RF (100 mg/kg body weight), inoculum (2 mL) + Q3G-RF (200 mg/kg body weight), and inoculum (2 mL) + Q3G-RF (400 mg/kg body weight). Values are expressed as mean ± standard error of mean (n = 6). Significant differences from the sham control group are indicated by † and from negative control by #, p < 0.05