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Table 5 Effect of intratumoral injection with 109cells/ml of S. cerevisiae and S. cerevisiae-GNSs on Cytochrome c concentration in the negative, positive, and treatment groups

From: Gold nanoparticles combined baker’s yeast as a successful approach for breast cancer treatment

Parameter

Cytochrome c (pg/ml)

Groups

Mean ± S.E

Significance to normal

Significance to tumor

Significance to yeast group

Negative control (normal)

7.68 ± 0.38

–––––-

##

 + 

Positive control (tumor)

4.73 ± 0.33

**

–––––-

 +  + 

S. cerevisiae 109 (yeast group)

15.75 ± 1.58

*

##

–––––-

S. cerevisiae–GNSs

24.13 ± 1.26

**

###

 + 

  1. Significance relative to normal: *P ≤ 0.05 and**P ≤ 0.01; significance relative to tumor: ##P ≤ 0.01 and ###P ≤ 0.001; significance relative to yeast: +P ≤ 0.05 and ++P ≤ 0.01