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Table 4 Effect of intratumoral injection with 109 cells/ml of S. cerevisiae and S. cerevisiae-GNSs on Bax concentration in the negative, positive, and treatment groups

From: Gold nanoparticles combined baker’s yeast as a successful approach for breast cancer treatment

Parameter

Bax (ng/ml)

Groups

Mean ± S.E

Significance to normal

Significance to tumor

Significance to yeast group

Negative control (normal)

250.00 ± 5.77

–––––-

#

 +  + 

Positive control (tumor)

143.43 ± 12.09

*

–––––-

 +  +  + 

S. cerevisiae 109 (yeast group)

370.00 ± 5.77

**

###

–––––-

S. cerevisiae–GNSs

546.67 ± 24.04

**

###

 +  + 

  1. Significance relative to normal: *P ≤ 0.05 and **P ≤ 0.01; significance relative to tumor: #P ≤ 0.05 and ###P ≤ 0.001; significance relative to yeast: ++P ≤ 0.01 and +++P ≤ 0.001