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Journal of Genetic Engineering and Biotechnology

Table 2 Effect of intratumoral injection with 109 cells/ml of S. cerevisiae and S. cerevisiae-GNSs on Bcl-2 concentration in the negative, positive, and treatment groups

From: Gold nanoparticles combined baker’s yeast as a successful approach for breast cancer treatment

Parameter

Bcl-2 (ng/ml)

Groups

Mean ± S.E

Significance to normal

Significance to tumor

Significance to yeast group

Negative control (normal)

1.35 ± 0.07

–––––-

##

 + 

Positive control (tumor)

4.73 ± 0.33

**

–––––-

 +  + 

S. cerevisiae 109

(yeast group)

1.04 ± 0.01

*

##

–––––-

S. cerevisiae–GNSs

0.55 ± 0.06

**

##

 +  + 

  1. Significance relative to normal: *P ≤ 0.05 and **P ≤ 0.01; significance relative to tumor: ##P ≤ 0.01; significance relative to yeast: + P ≤ 0.05 and +  + P ≤ 0.01
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