Fig. 9
From: Gold nanoparticles combined baker’s yeast as a successful approach for breast cancer treatment
Liver tissue sections of A, B showing preserved architecture with ordinary hepatocytes (thin black arrows) with small, regular, rounded nuclei disposed in single thick plates, radiating from the central vein (black oval shape). C, D DMBA-injected rats showed disturbed architecture with prominent hydropic degeneration within hepatocytes (green arrows), proliferating bile ducts (thick black arrows), periductal bands of fibrosis (white arrows), and mixed inflammatory cell aggregates (black star). E, F DMBA-injected rats treated with injected yeast showed preserved architecture and numerous ordinary liver cells; with minimal residual hydropic degeneration (green arrows) within scattered hepatocytes. G, H DMBA-injected rats treated with injected nanogold-carrying yeast showed a picture approximating control, with mostly ordinary hepatocytes (thin black arrows) except for minimal microvesicles within a few liver cells (H&E × 200)