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Journal of Genetic Engineering and Biotechnology
Fig. 2 | Journal of Genetic Engineering and Biotechnology

Fig. 2

From: The potential role of the KFG and KITLG proteins in preventing granulosa cell apoptosis in Bubalus bubalis

Fig. 2

Bcl-2, Bcl-xL and BAX genes expression in granulosa cells with KGF and KITLG. A, B A significant increase in Bcl-2 and Bcl-xL expression was observed and Bax was down-regulated in bovine granulosa cells with KGF and KITLG treatment. C Treatment of granulosa cells with combination of KGF and KITLG increased the expression levels of anti-apoptotic proteins (Bcl-2 and Bcl-xL) and decreased significantly (**P < 0.01) the pro-apoptotic protein Bax at 10 ng/ml. K represents the KGF, KITLG is denoted by KL and A is KGF+KITLG. The dose concentration are defined as 10, 20, and 50 ng/ml for both KGF and KITLG. Values are expressed as the mean ± SD of three experiments; *P < 0.05, **P < 0.01, ***P < 0.001 vs. the control (non-treated)

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