Table 4 Identified MoRF regions in HEV ORF2 proteins
PROTEIN | DISOPRED3 (cutoff = ≥ 0.5) | IUPRED3 ANCHOR (cutoff = ≥ 0.5) | IUPRED2A ANCHOR (cutoff = ≥ 0.5) |
|---|---|---|---|
JF443720 | [1-11] MRPRPILLLFL [25-34] PSGRRRGRRS [70-71] GA [89-100] QAQRPAAASRRR [218-219] PT [448-455] QDRPTPSP [457-458] PS [603-618] HSALALLEDTLDYPAR [647-659] QRLKMKVGKTREL | [1-21] MRPRPILLLFLMFLPMLPAPP [30-136] RGRRSGGSGGGFWGDRVDSQPFAPYIHPTNPFAPDVTAAAGAGPRVRQPVRPLGSAWRDQAQRPAAASRRRPTTAGAAPLTAVAPAHDTPPVPDVDSRGAILRRQYN [425-439] AIPHDIDLGESRVVI | [1-21] MRPRPILLLFLMFLPMLPAPP [30-136] RGRRSGGSGGGFWGDRVDSQPFAPYIHPTNPFAPDVTAAAGAGPRVRQPVRPLGSAWRDQAQRPAAASRRRPTTAGAAPLTAVAPAHDTPPVPDVDSRGAILRRQYN [425-439] AIPHDIDLGESRVVI |
M74506 | [1-11] MRPRPLLLLFLLFL [21-35] PTGQPSGRRRGRRSG [45-49] SAASR [121-123] PVP [134] R [603-618] RSALALLEDTFDYPGR [647-659] QRLKVKVGKTREL | [2-20] RPRPLLLLFLLFLPMLPAP [35-138] GGTGGGFWGDRVDSQPFAIPYIHPTNPFAPDVAAASGSGPRLRQPARPLGSTWRDQAQRPSAASRRRPATAGAAALTAVAPAHDTSPVPDVDSRGAILRRQYNL [424-441] VAIPHDIDLGDSRVVIQD | [2-20] RPRPLLLLFLLFLPMLPAP [35-138] GGTGGGFWGDRVDSQPFAIPYIHPTNPFAPDVAAASGSGPRLRQPARPLGSTWRDQAQRPSAASRRRPATAGAAALTAVAPAHDTSPVPDVDSRGAILRRQYNL [424-441] VAIPHDIDLGDSRVVIQD |
AB222182 | [1-11] MRPGAVLLLLL [22-35] AGQPSGRRRGRRSG [95-96] SA [449-454] QDRPTP [456-458] PAP [605-618] SALAVLEDTADYPA [647-660] LQRLKMKVGKTRES | [4-18] GAVLLLLLVFLPMLP [37-138] AGGGFWGDRVDSQPFALPYIHPTNPFVADVVSQSGAGARPRQPPRPLGSAWRDQSQRPSAPPRRRSTPAGAAPLTAISPAPDTAPVPDVDSRGAILRRQYNL [425-442] ITIPHDIDLGDSRVVIQDYDNQHEQD | [4-18] GAVLLLLLVFLPMLP [37-138] AGGGFWGDRVDSQPFALPYIHPTNPFVADVVSQSGAGARPRQPPRPLGSAWRDQSQRPSAPPRRRSTPAGAAPLTAISPAPDTAPVPDVDSRGAILRRQYNL [425-442] ITIPHDIDLGDSRVVIQDYDNQHEQD |
GU119961 | [1-5] MNNMF [19-24] ALLFLL [42] R [44-45] RG [106-115] QRPAASSRRR [463-468] QDRPTP [470-472] PAP [619-633] SVLAALEDTVDYPAR [661-674] LQRLKMKVGKTREY | [22-29] FLLLVLLP [53-146] GGFWGDRVDSQPFALPYIHPTNPFASDISTAAGAGARPRQPARPLGSAWRDQSQRPAASSRRRSAPAGASPLTAVAPAPDTAPVPDIDSRGAIL [439-455] IAIPHDIDLGESRVVIQ | [22-29] FLLLVLLP [53-146] GGFWGDRVDSQPFALPYIHPTNPFASDISTAAGAGARPRQPARPLGSAWRDQSQRPAASSRRRSAPAGASPLTAVAPAPDTAPVPDIDSRGAIL [439-455] IAIPHDIDLGESRVVIQ |
AB573435 | [1-5] MNNMF [21-24] LLLL [85-86] GT [462-472] EQDRPTPSPAP [618-633] HAALAVLEDTVDYPAR [662-674] QRLKMRVGKTREF | [56-153] WGDRVDSQPFALPYIHPTNPFASDTIAATGTGARSRQSARPLGSAWRDQTQRPPAASRRRSTPTGASPLTAVAPAPDTRPVPDVDSRGAILRRQYNLS [439-454] GIAIPHDIDLGDSRVVI | [56-153] WGDRVDSQPFALPYIHPTNPFASDTIAATGTGARSRQSARPLGSAWRDQTQRPPAASRRRSTPTGASPLTAVAPAPDTRPVPDVDSRGAILRRQYNLS [439-454] GIAIPHDIDLGDSRVVI |
AB602441 | [1-12] MRPRAVLLLFLM [21-35] PAGQPSGRRRGRRSG [71-72] GA [90] Q [92-99] QRPSASAR [449-454] QDRPTP [456-458] PAP [604-619] HAATAALEDTADSPAR [447-660] LQRLKMKVGKSREF | [2-19] RPRAVLLLFLMLLPMLPA [37-139] SGGGFWGDRVDSQPFALPYIHPTNPFASDVSTSAGAGARARQAARPLGSAWRDQSQRPSASARRRPTPAGASPLTAVAPAPDTTPVPDVDSRGAILRRQYNLS [424-439] GIAIPHEIDLGDSRVTI | [2-19] RPRAVLLLFLMLLPMLPA [37-139] SGGGFWGDRVDSQPFALPYIHPTNPFASDVSTSAGAGARARQAARPLGSAWRDQSQRPSASARRRPTPAGASPLTAVAPAPDTTPVPDVDSRGAILRRQYNLS [424-439] GIAIPHEIDLGDSRVTI |
KJ496143 | [1-11] MRPRAILLLLL [21-35] PAGQSSGRRRGRRSG [95-96] PA [448-458] EQDRPTPSPAP [606-619] ALAVLEDTTDHPAR [648-660] QRLKMKVGKTREY | [7-17] LLLLLLLLPML [42-138] WGDRVDSQPFALPYIHPTNPFAADVSAASRSGTGLRQSARPLGTAWRDQSQRPPASTRRRSAPSGAAPLTAVAPAPGTAPVPDVDSRGAVLRRQYNL [426-438] AIPHDSRV | [7-17] LLLLLLLLPML [42-138] WGDRVDSQPFALPYIHPTNPFAADVSAASRSGTGLRQSARPLGTAWRDQSQRPPASTRRRSAPSGAAPLTAVAPAPGTAPVPDVDSRGAVLRRQYNL [426-438] AIPHDSRV |
KX387865 | [1-11] MCTRAVLLLFL [22-35] AGQPSGRRRGRRSG [96] A [449-454] QDRPTP [456-458] PAP [605-618] SALAVLEDTIDYPA [647-660] IQRLKMKVGKTRES | [6-16] VLLLFLLLLP [41-138] WGDRVDSQPFALPYIHPTNPFVADITSSSGAGSRSRQPSRPLGTAWRDQSQRPAAPTRRRSTPAGAAPLTATAPASGTTPVPDVDSRGAILRRQYNL [425-441] IAIPHDIDLGESRVVIQ | Â |