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Table 5 Common hub genes between the top ten hub genes obtained by 12 different topological analysis methods

From: Identification of hub genes involved in cisplatin resistance in head and neck cancer

Names

Total

Genes

Betweenness, bottle neck, closeness, degree, EPC, EcCentricity, MCC, MNC, radiality, and stress

2

VEGFA, CTNNB1

Betweenness, bottle neck, closeness, degree, EPC, MCC, MNC, radiality, and stress

3

EGFR, HIF1A, TP53

Betweenness, closeness, degree, EPC, EcCentricity, MCC, MNC, radiality, and stress

1

STAT3

Betweenness, bottle neck, closeness, degree, EcCentricity, MNC, radiality, and stress

1

TNF

Betweenness, closeness, degree, EPC, MCC, MNC, radiality, and stress

1

PTEN

Closeness, degree, EPC, EcCentricity, MCC, MNC, and radiality

1

CCND1

Betweenness, bottle neck, degree, EPC, MNC, and stress

1

IL6

Closeness, MCC, radiality, and stress

1

ERBB2

EPC, EcCentricity and MCC

1

CDH1

Clustering coefficient and DMNC

3

ERCC4, ERCC5, AXL

Betweenness

1

MTOR

Bottle neck

3

CD44, CDKN2A, UGT1A1

Clustering coefficient

7

HDGF, CXCR2, SLC16A1, PAK1, ABCC2, GDF15, KDM4C

DMNC

7

BMP4, IGFBP3, JAK2, IGF1R, MET, MUC1, HGF

EcCentricity

4

TERT, PIK3CA, EZH2, AR