Table 5 Fold expression of miRNA-192 in patients with early and advanced stage of fibrosis compared with healthy controls as determined by RT-qPCR

NAFLD cases with early fibrosis

miR-192

miR-192

CT

miR-16

CT (normalize)

ΔCt

ΔΔCt

Mean fold change

p-value

Regulation

28.81 ± 1.99

17.67 ± 2.8

 11.1±2.59

−1.66 ± 2.59

18.43 ± 47.8

0.017*

Upregulated

NAFLD cases with advanced fibrosis

miR-192

CT

miR-16

CT (normalize)

Mean ΔCt

Mean ΔΔCt

Mean fold change

p-value

Regulation

28.67 ± 4.16

14.89 ± 2.06

13.78 ± 4.8

0.98 ± 4.8

5.36 ± 8.89

0.530

Upregulated