Table 4 Fold expression of miRNA-34a in patients with early and advanced stage of fibrosis compared with those from healthy controls as determined by RT-qPCR
From: Significance of MiRNA-34a and MiRNA-192 as a risk factor for nonalcoholic fatty liver disease
NAFLD cases with early fibrosis | |||||||
miRNA-34a | miRNA-34a CT | miR-16 CT (normalize) | ΔCt | ΔΔCt | Mean fold change | p-value | Regulation |
21.81 ± 4.2 | 17.37 ± 3.16 | 4.44 ± 4.87 | 3.19 ± 4.87 | 4.02 ± 11.49 | 0.05* | Upregulated | |
NAFLD cases with advanced fibrosis | |||||||
miRNA-34a CT | miR-16 CT (normalize) | MeanΔCt | MeanΔΔCt | Mean fold change | p-value | Regulation | |
20.05 ± 2.59 | 14.89 ± 2.06 | 5.16 ± 3.87 | 3.9 ± 3.87 | 0.65 ± 1.17 | 0.831 | Down | |