Table 2 Clinical characteristics of cases with early fibrosis and advanced fibrosis as well as controls

Age (yrs.)

31.7 ± 10.7

43.21 ± 12.7^a**

46.97 ± 10.74^a**

< 0.001**

Gender^a

0.032*

 Male/female

16/14

9/19

7/25

 Percentage of male

53.3%

32.1%

21.9%

Hypertension

0.043*

 No

30 (100%)

23 (82.1%)

26 (81.3%)

 Yes

0 (0%)

5 (17.9%)

6 (18.8%)

Diabetes

< 0.001**

 Absent

30 (100%)

13 (46.4%)

16 (50%)

 Oral hypoglycemic

0 (0%)

7 (25%)

11 (34.4%)

 On insulin

0 (0%)

8 (28.6%)

5 (15.6%)

BMI (kg/m²)

23.99 ± 1.8

31.11 ± 4.8^a**

35.03 ± 8.4^a**^,b*

< 0.001**

Laboratory variables

 Fasting blood glucose (mg/dl)

93.24 ± 12.1

127.29 ± 63.1^a*

149.87 ± 94.9^a**

0.01**

 HB (g/dL)

12.7 ± 1.34

11.4 ± 1.3 ^a**

11.8 ± 0.6

0.015*

 Platelets (10³/μL)

255.04 ± 58.3

234.53 ± 74

165 ± 27.2^a*

0.064

 Total leucocytic count (10³/μL)

6.81 ± 1.7

6.83 ± 1.8

4.39 ± 0.89^a,b**

0.072

 AST (U/L)

23.75 ± 5.8

23.87 ± 7.44

27.85 ± 13.7

0.189

 ALT (U/L)

28.5 ± 6.5

35.9 ± 20.9

23.4 ± 12.4^b**

0.006**

 Total bilirubin (mg/dL)

0.67 ± 0.21

0.68 ± 0.3

0.64 ± 0.3

0.815

 ALP (U/L)

115.46 ± 15.6

142.2 ± 45.4^a*

120.2 ± 55.9

0.04*

 GGT (U/L)

37.46 ± 23.8

75.08 ± 56.6^a*

52.6 ± 30.3

0.005**

 Total protein (g/dL)

7.88 ± 0.27

7.81 ± 0.43

7.37 ± 0.44^a,b**

< 0.001**

 Serum albumin (g/dL)

3.8 ± 0.28

3.74 ± 0.38

3.78 ± 0.44

0.833

 Cholesterol (mg/dl)

102.34 ± 24.14

162.8 ±32.1^a**

160.2 ± 43.5^a**

< 0.001**

 Triglycerides (mg/dl)

145.6 ± 29.2

166.5 ± 85.9

156.4 ± 93.2

0.586

 HDL (mg/dl)

55.14 ± 12.3

53.7 ± 12.9

48.4 ± 8.9^a*

0.071

 LDL (mg/dl)

100.1 ± 16.2

127.9 ± 33.5^a**

113.2 ± 27.6^b*

0.001**