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Journal of Genetic Engineering and Biotechnology

Table 6 Serum level of TNF-alpha (pg/ml) distribution according to genotypes in the studied groups

From: Estimating the role of single-nucleotide polymorphism (rs1800629)-308 G/A of TNF-alpha gene as genetic marker associated with angina pectoris in a sample of Iraqi patients

Subject groups

Serum level of TNF-alpha (pg/ml) ) mean ± SD

p-value

GG

GA

AA

Control (n = 100)

29.3 ± 8.9A, a

36.3 ± 8.7A, a

40.6 ± 11.7A, a

0.42 (NS)

Stable angina (n = 100)

74 ± 20.3B, a

79.7 ± 21.6B, a

95.2 ± 30.1B, b

0.027 (S)

Unstable angina (n = 100)

73.6 ± 12.4B, a

92.8 ± 18.2C, b

106.5 ± 19.7B, b

0.033 (S)

P-value

0.03 (S)

0.000 (S)

0.04 (S)

 
  1. ANOVA test. Different capital letters mean there are significant differences between subject groups with the same genotype, and different small letters mean there are significant differences between genotypes with the same group. NS non-significant P > 0.05; S significant P ≤ 0.05
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