Table 2 Prediction of mutations’ deleterious effects
From: An in silico analysis of rpoB mutations to affect Chlamydia trachomatis sensitivity to rifamycin
SNP | PredictSNP | MAPP | PhD-SNP | PolyPhen-1 | PolyPhen-2 | SIFT | SNAP | nsSNP-Analyzer | PANTHER |
|---|---|---|---|---|---|---|---|---|---|
V136F | D | D | D | D | D | D | D | D | D |
Q458K | D | D | D | D | D | D | D | D | - |
V466A | D | D | D | N | N | D | D | D | N |
A467T | D | D | D | D | D | D | D | D | N |
H471N | D | N | D | N | D | D | D | N | N |
H471Y | D | D | D | D | D | D | D | D | D |
H471L | D | D | D | D | D | D | D | D | D |
I517M | D | D | D | D | D | D | D | D | D |