Analysis of selected polymorphisms in FOXP3 gene in a cohort of Egyptian patients with schizophrenia

Journal of Genetic Engineering and Biotechnology

Table 6 Comparison of the studied SNPs genetic variability between healthy control subjects in the current study and main ethnic groups in the 1000 genome project

SNP ID	Population	N	MA	MAF	Ho	He	Fst versus current
rs3761548	Current study	160	A	0.173	0.197	0.279
	All populations	2504	A	0.237	0.159	0.361	0.007
	African	661	A	0.047	0.045	0.092	0.039
	American	347	A	0.292	0.193	0.416	0.021
	East Asia	504	A	0.166	0.139	0.275	0.000
	European	503	A	0.478	0.282	0.798	0.103
	South Asia	489	A	0.280	0.184	0.405	0.017
rs3761549	Current study	160	T	0.185	0.208	0.282
	All populations	2504	T	0.144	0.111	0.248	0.001
	African	661	T	0.023	0.018	0.050	0.079
	American	347	T	0.084	0.075	0.153	0.030
	East Asia	504	T	0.190	0.163	0.309	0.000
	European	503	T	0.121	0.103	0.213	0.013
	South Asia	489	T	0.330	0.219	0.441	0.019
rs2232365	Current study	160	A	0.345	0.274	0.450
	All populations	2504	A	0.410	0.215	0.483	0.005
	African	661	A	0.187	0.154	0.295	0.062
	American	347	A	0.546	0.222	0.497	0.017
	East Asia	504	A	0.641	0.236	0.460	0.056
	European	503	A	0.401	0.262	0.483	0.000
	South Asia	489	A	0.383	0.223	0.473	0.001

N number within each population, MA minor allele, MAF minor allele frequency, Ho observed heterozygosity, He expected heterozygosity, uHe unbiased expected heterozygosity, Fst fixation index