Fig. 1

An overview of the general process for SAR-CoV-2 protein production in BEV. A baculovirus vector encoding the SARS-CoV-2 protein is transformed into competent E. coli. Translocation occurred in E. coli where the gene encoding SARS-CoV-2 protein was transferred from the donor plasmid to the bacmid. The bacmid is extracted from E. coli and used to transfect insect cells for the generation of recombinant baculoviruses. The recombinant baculovirus is further amplified for up scaling of the recombinant protein production. High-scale protein production is produced in bioreactors or by silkworm larvae. The protein is purified and analyzed before being used for various applications