A novel antimicrobial peptide found in Pelophylax nigromaculatus

Journal of Genetic Engineering and Biotechnology

Table 6 The combination effects of Nigrocin-PN with different antibiotics treated on several microbial strains

Strains	Norfloxacin (lowest FICI)	Ampicillin (lowest FICI)	Vancomycin (lowest FICI)	Gentamicin (lowest FICI) c
S. aureus (NCTC 10,788)	0.625 (NI^a)	0.375 (S^b)	0.625 (NI)	0.620 (NI)
MRSA (NCTC 12,493)	\^c	\	1.125 (NI)	0.500 (S)
E. coli (NCTC 10,418)	0.625 (NI)	\	\	0.750 (NI)
C. albicans (NYCY 1467)	0.500 (S)	\	0.375 (S)	\

“NI^a” represents “no interaction.”
“S^b” represents “synergy.”
“\^c” represents “not studied.” Only the MICs of antibiotics fell between 64 and 0.125 µM were chosen to study the combination effect