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Table 1 Physicochemical properties of SpPMO and other class B monooxygenases used in the study

From: In silico structural, phylogenetic and drug target analysis of putrescine monooxygenase from Shewanella putrefaciens-95

Accession no. Name of the protein Organism No of amino acids MW (kDa) pI Instability index Solubility index Aliphatic index GRAVY
Putrescine monooxygenase
 QBX90611.1 SpPMO Shewanella putrefaciens 95 505 57.24 6.46 40.56 0.143 78.85 −0.359
 ACK46161.1 SbNMO Shewanella baltica 501 56.76 6.24 43.51 0.154 79.48 −0.346
 ADV54887.1 Sp200NMO Shewanella putrefaciens 200 505 57.21 6.37 40.16 0.147 78.48 −0.359
 ABP76132.1 SpCN32NMO Shewanella putrefaciens CN32 505 57.22 6.31 41.97 0.147 78.48 −0.357
 AOR50757.1 GrNMO Gordonia ruberipertincta 438 48.84 5.03 38.24 0.394 89.66 −0.17
 AGJ55094.1 StrNMO Streptomyces 428 48.26 5.37 37.81 0.245 79.39 −0.356
 CFO04355.1 BpNMO Bordetella pertussis 478 54.95 7.32 47.78 0.081 80.86 −0.489
Cadeverine monooxygenase
 CBA23306.1 EaNMO Erwinia amylovora 430 50.17 5.72 45.78 0.180 78.7 −0.500
Lysine monooxygenases
 WP_103556989.1 EcNMO Escherichia coli 595 67.77 5.63 36.32 0.054 97.09 −0.094
 NP_216894.1 MtNMO Mycobacterium tuberculosis 431 46.94 6.17 26.65 0.227 88.54 −0.164
 WP_099421877.1 NfNMO Nocardia farcinica 456 49.71 7.94 33.01 0.273 89.23 −0.246
Ornithine monooxygenases
 NP_251076.1 PaNMO Pseudomonas aeruginosa 443 49.48 6.03 39.44 0.134 90.32 −0.252
 WP_043726233.1 KtzNMO Kutzneria spp. 424 47.29 5.51 40.11 0.412 78.63 −0.325
 XP_755103.1 AfNMO Aspergillus fumigates 501 56.87 8.78 49.32 0.244 80.78 −0.523
 WP_039794392.1 AlNMO Amycolatopsis alba 447 49.44 5.08 34.11 0.468 86.58 −0.189
Flavin-containing monooxygenases
 NP_001269621.1 HsFMO Homo sapiens 536 60.81 6.58 36.29 0.289 87.09 −0.053
 AAM18566.2 MaFMO Methylophaga aminisulfidivorans 456 52.99 5.13 33.34 0.469 65.26 −0.543
Baeyer-Villiger monooxygenase
 CAD10801.1 XfBVMO Xanthobacter flavus 446 60.32 5.93 25.67 0.283 77.4 −0.235