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Table 2 Determination of succinate dehydrogenase (SDH) and coenzyme Q reductase (complex II) activities by IC50

From: Study of the inhibitory effects of chrysin and its nanoparticles on mitochondrial complex II subunit activities in normal mouse liver and human fibroblasts

Relative enzyme activity % Negative control (untreated cells) Chrysin
Mean± SEM
*p value
CNPs
Mean± SEM
*p value
CCNPs
Mean± SEM
*p value
5-Fluorouracil
Mean± SEM
*p value
Succinate dehydrogenase by MTT test 100 ± 0 40.14±0.03
P <0.0001
90.9± 0.005
P <0.0001
86.7±0.041
P <0.0001
89± 0.02
P <0.0001
Ubiquinone reductase by DCPI dye 100 ± 0 70.90±0.003
P <0.0001
86.74 ± 0.005
P <0.0001
60.8 ±0.002
P <0.0001
80.23 ±0.02
P < 0.0001
  1. *p value versus the negative control (untreated cells)