Journal of Genetic Engineering and Biotechnology

Table 3 The antagonistic effect of P. columbinus extract in alleviating the toxic effect of CTX on oxidative stress markers in the experimental rat groups

From: Assessment role of total phenols and flavonoids extracted from Pleurotus columbinus mushroom on the premature ovarian failure induced by chemotherapy in rats

Groups	TBRAS (nmol/ml)	CAT (U/g)	SOD (U/g)	GSH (U/mg)	GSH PX (U/g)
Control	0.37 ± 0.02^b	14.70 ± 1.67^a	84.03 ± 6.09^a	10.27 ± 0.81^a	10.23 ± 0.56^a
CTX	1.69 ± 0.05^a	6.05 ± 0.54^b	37.33 ± 3.41^b	4.48 ± 0.33^b	4.28 ± 0.06^b
TP	0.39 ± 0.03^b	14.13 ± 1.32^a	90.70 ± 5.23^a	10.02 ± 0.63^a	10.01 ± 0.71^a
CTX+TP	0.54 ± 0.04^b	13.90 ± 1.12^a	75.83 ± 3.44^a	8.92 ± 0.41^a	9.993 ± 0.56^a

Each value represents mean ± SE (n = 8). a and b denote significant difference from normal control, CTX induced POF, P. columbines extract control and POF+P. columbinus (before and after) groups, respectively, p < 0.05 (one-way ANOVA followed by post hoc Tukey)

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