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Journal of Genetic Engineering and Biotechnology
Fig. 3 | Journal of Genetic Engineering and Biotechnology

Fig. 3

From: Assessment role of total phenols and flavonoids extracted from Pleurotus columbinus mushroom on the premature ovarian failure induced by chemotherapy in rats

Fig. 3

a Control group: Interstitial stromal cells with primary and secondary follicles and few corpus luteum were detected (a and b). c Control rats received P. columbinus extract; there is no alteration in the primary and secondary follicles. d Group of rats injected CTX: Sever congestion was detected in the medullary blood vessels associated with mature follicle and corpus luteum in the cortex. There was congestion in the medullary portion associated with few atretic follicles as well as multiple corpus luteum (e). There was multiple corpus luteum with few follicles as well as interstitial stromal cells in the cortex. Sever congestion was detected in the medullary blood vessels. There was multiple corpus luteum with few follicles as well as interstitial stromal cells in the cortex (e and f). Sever congestion was detected in the medullary blood vessels (g). (h and i) CTX+ P. columbinus extract (100 mg/kg): Interstitial stromal cells with normal primary and secondary follicles. j Oral treatment of P. columbinus extract (100 mg/kg) on the number of follicles in rats treated with CTX chemotherapy

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