Table 1 General details on the 7 candidate SNPs in the CRS score
From: Evaluation of seven gene signature for predicting HCV recurrence post-liver transplantation
Genes | Gene name | rs number | Chromosome | Gene biological functions |
|---|---|---|---|---|
AZIN1 | Antizyme inhibitor | rs62522600 | (Chr8) | Polyamine biosynthesis, cell proliferation [22] |
TLR4 | Toll-like receptor 4 | rs4986791 | (Chr9) | Important pathogen recognition receptors [23] |
TRPM5 | Transient receptor potential cation channel subfamily member 5 | rs886277 | (Chr11) | Taste responses, specific physiological function in liver is unknown [24]. |
AP3S2 | Adaptor-related protein complex 3 sigma 2 subunit | rs2290351 | (Chr15) | Unknown |
DESGS1 | Degenerative spermatocyte homolog1 lipid desaturase | rs4290029 | (Chr1) | Lipid metabolism and transport, cell growth [25] |
STXBP5L | Syntaxin binding protein | rs17740066 | (Chr3) | Inhibits endothelial exocytosis [26] |
AQP2 | Aquaporin 2 | rs2878771 | (Chr12) | Water reabsorption, vasopressin regulation [27] |