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Table 1 Clinical and laboratory data of the studied groups

From: A novel model based on interleukin 6 and insulin-like growth factor II for detection of hepatocellular carcinoma associated with hepatitis C virus

Variables Cirrhosis group
(n = 60)
HCC group
(n = 155)
P value
Age (year) 57.1 ± 8.3 59.4 ± 7.1 0.1
Gender
 Male no., % 26 (43%) 84 (54%) 0.17
 Female no., % 34 (57%) 71 (46%)
Liver function tests
 Alanine aminotransferase (U/L) 28 (22-40) 33 (24.5-64) 0.02
 Aspartate aminotransferase (U/L) 31 (22-50) 40 (28.7-70) 0.049
 Total bilirubin (mg/dl) 0.9 (0.7-1.2) 1.2 (0.8-1.9) 0.13
 Albumin (g/L) 34.2 ± 7.1 33.6 ± 5.0 0.48
 Prothrombin—INR 1.27 ± 0.2 1.34 ± 0.4 0.13
Hematological tests
 Platelet count (× 109/L) 136 (77-171.5) 92.5 (61.5-153) 0.03
 HCC tumor marker
  α—fetoprotein (U/L) 11 (5.5-18) 65.9 (7.8-514) 0.03
  Interleukin 6 (pg/ml) 10.3 (7-18.8) 18.9 (12.4-45.1) < 0.001
  Insulin-like growth factor II (pg/ml) 2.6 (2-10) 34 (11-306.5) 0.001
 Child-Pugh score; n (%)
  Child A 30 (50%) 120 (77.4%) < 0.0001
  Child B 30 (50%) 35 (22.6%)