Table 1 Clinical and laboratory data of the studied groups
Variables | Cirrhosis group (n = 60) | HCC group (n = 155) | P value |
|---|---|---|---|
Age (year) | 57.1 ± 8.3 | 59.4 ± 7.1 | 0.1 |
Gender | |||
Male no., % | 26 (43%) | 84 (54%) | 0.17 |
Female no., % | 34 (57%) | 71 (46%) | |
Liver function tests | |||
Alanine aminotransferase (U/L) | 28 (22-40) | 33 (24.5-64) | 0.02 |
Aspartate aminotransferase (U/L) | 31 (22-50) | 40 (28.7-70) | 0.049 |
Total bilirubin (mg/dl) | 0.9 (0.7-1.2) | 1.2 (0.8-1.9) | 0.13 |
Albumin (g/L) | 34.2 ± 7.1 | 33.6 ± 5.0 | 0.48 |
Prothrombin—INR | 1.27 ± 0.2 | 1.34 ± 0.4 | 0.13 |
Hematological tests | |||
Platelet count (× 109/L) | 136 (77-171.5) | 92.5 (61.5-153) | 0.03 |
HCC tumor marker | |||
α—fetoprotein (U/L) | 11 (5.5-18) | 65.9 (7.8-514) | 0.03 |
Interleukin 6 (pg/ml) | 10.3 (7-18.8) | 18.9 (12.4-45.1) | < 0.001 |
Insulin-like growth factor II (pg/ml) | 2.6 (2-10) | 34 (11-306.5) | 0.001 |
Child-Pugh score; n (%) | |||
Child A | 30 (50%) | 120 (77.4%) | < 0.0001 |
Child B | 30 (50%) | 35 (22.6%) | |