Table 1 Demographic and laboratory features of the studied groups

 Male (no, %)

52 (52%)

106 (49.5%)

0.38

-

-

 Female (no, %)

48 (48%)

108 (50.5%)

Age (years)

54.1±15.8

52.8 ± 10.5

0.39

-

-

BMI (kg/m²)

23.7±4.3

30.2±5.9

< 0.0001

2.8 (1.7–3.5)

0.001

Hemoglobin (g/L)

113±18

113±18

0.97

-

-

Glucose (mg/dl)

100±16

110±13

< 0.0001

1.7 (1.2–1.9)

0.007

Alanine aminotransferase (U/L)

30.3 ±5.1

35.2± 7.2

< 0.0001

2.6 (1.6–2.9)

< 0.0001

Aspartate aminotransferase (U/L)

33.1±7.4

37.3±8.0

< 0.0001

1.2 (0.98–1.1)

0.097

Gamma-glutamyl transferase (U/L)

34.0±9.1

43.0±16.8

< 0.0001

0.93 (0.9–1.0)

0.43

Albumin (g/L)

40.2 ±2.1

38.3±2.1

0.09

-

-

Total bilirubin (mg/dl)

0.77±0.2

0.86±0.3

< 0.0001

0.2 (0.0–0.76)

0.55

C-reactive protein (mg/L)

2.1 (2–3)

6.5 (4–12)

< 0.0001

4.5 (2.6–7.0)

< 0.0001

Alfa fetoprotein (U/L)

6.0 (5–7)

7.0 (5–9)

< 0.0001

1.6 (1.1–1.7)

0.01

International normalized ratio-PT

0.98±0.1

1.1±0.2

< 0.0001

0.92 (0.1–1.1)

0.44

Cholesterol (mg/dl)

142.8±22.0

181.5±27.0

< 0.0001

3.1 (2.5–4.9)

< 0.0001

Triglycerides (mg/dl)

141.6±17.7

168.1±34.5

< 0.0001

1.6 (1.2–1.8)

0.01

High-density lipoprotein (mg/dl)

42.5±0.8.3

38.6±9.3

< 0.0001

0.93 (0.84–1)

0.18

Low-density lipoprotein (mg/dl)

104.4±10.8

115.0±23.2

< 0.0001

1.5 (1.2–1.9)

0.03

Vitamin D (pmol/L)

88 (77–116)

52 (34–78)

< 0.0001

0.98 (0.95–1.1)

0.151

MiRNA-34 (fold of change)

2.0 (1.4–4.0)

6.8 (2.0–32)

< 0.0001

2.1 (1.5–2.3)

0.0004