Skip to main content

Table 1 Demographic and laboratory features of the studied groups

From: NAFLD mark: an accurate model based on microRNA-34 for diagnosis of non-alcoholic fatty liver disease patients

Parameter Univariate analysis Multivariate analysis
Healthy
(n=100)
All NAFLD
(n= 214)
p value Odds ratio (95% CI) p value
Gender
 Male (no, %) 52 (52%) 106 (49.5%) 0.38 - -
 Female (no, %) 48 (48%) 108 (50.5%)
Age (years) 54.1±15.8 52.8 ± 10.5 0.39 - -
BMI (kg/m2) 23.7±4.3 30.2±5.9 < 0.0001 2.8 (1.7–3.5) 0.001
Hemoglobin (g/L) 113±18 113±18 0.97 - -
Glucose (mg/dl) 100±16 110±13 < 0.0001 1.7 (1.2–1.9) 0.007
Alanine aminotransferase (U/L) 30.3 ±5.1 35.2± 7.2 < 0.0001 2.6 (1.6–2.9) < 0.0001
Aspartate aminotransferase (U/L) 33.1±7.4 37.3±8.0 < 0.0001 1.2 (0.98–1.1) 0.097
Gamma-glutamyl transferase (U/L) 34.0±9.1 43.0±16.8 < 0.0001 0.93 (0.9–1.0) 0.43
Albumin (g/L) 40.2 ±2.1 38.3±2.1 0.09 - -
Total bilirubin (mg/dl) 0.77±0.2 0.86±0.3 < 0.0001 0.2 (0.0–0.76) 0.55
C-reactive protein (mg/L) 2.1 (2–3) 6.5 (4–12) < 0.0001 4.5 (2.6–7.0) < 0.0001
Alfa fetoprotein (U/L) 6.0 (5–7) 7.0 (5–9) < 0.0001 1.6 (1.1–1.7) 0.01
International normalized ratio-PT 0.98±0.1 1.1±0.2 < 0.0001 0.92 (0.1–1.1) 0.44
Cholesterol (mg/dl) 142.8±22.0 181.5±27.0 < 0.0001 3.1 (2.5–4.9) < 0.0001
Triglycerides (mg/dl) 141.6±17.7 168.1±34.5 < 0.0001 1.6 (1.2–1.8) 0.01
High-density lipoprotein (mg/dl) 42.5±0.8.3 38.6±9.3 < 0.0001 0.93 (0.84–1) 0.18
Low-density lipoprotein (mg/dl) 104.4±10.8 115.0±23.2 < 0.0001 1.5 (1.2–1.9) 0.03
Vitamin D (pmol/L) 88 (77–116) 52 (34–78) < 0.0001 0.98 (0.95–1.1) 0.151
MiRNA-34 (fold of change) 2.0 (1.4–4.0) 6.8 (2.0–32) < 0.0001 2.1 (1.5–2.3) 0.0004