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Table 6 Diagnostic performance of Livin/BIRC7 expression, catalase, and malondialdehyde (MDA) for differentiation between endometrial carcinoma and endometrial hyperplasia

From: Livin/BIRC7 gene expression as a possible diagnostic biomarker for endometrial hyperplasia and carcinoma

 

Livin/BIRC7 expression

Catalase

MDA

Cutoff

> 0.90

> 0.22

> 7.30

AUC

0.940

0.590

0.870

Sensitivity %

93.3%

36.7%

90.0%

Specificity %

86.7%

86.7%

83.3%

Accuracy

80%

23%

73%

PPV %

87.5%

73.3%

84.4%

NPV %

92.9%

57.8%

89.3%

95% CI

0.84-0.98

0.45-0.71

0.76-0.94

p value

< 0.001

0.24

< 0.001

  1. AUC: area under the curve, PPV: positive predictive value, NPV: negative predictive value, CI: confidence interval